Article
Neurosciences
Rahul Chandwani, Julia E. Kline, Karen Harpster, Jean Tkach, Nehal A. Parikh
Summary: The study aimed to derive micro- and macrostructural measures of sensorimotor white matter tract integrity from diffusion MRI in very preterm infants and determine their association with early diagnosis of cerebral palsy. Results showed that measures of sensorimotor tract integrity were significantly associated with early CP diagnosis, enhancing understanding of white matter changes contributing to CP development in VPT infants.
HUMAN BRAIN MAPPING
(2021)
Article
Public, Environmental & Occupational Health
Neda Razaz, Sven Cnattingius, Sarka Lisonkova, Shahrzad Nematollahi, Maryam Oskoui, K. S. Joseph, Michael Kramer
Summary: Cerebral palsy (CP) is the most common cause of childhood physical disability, and the causes are largely unknown. Maternal pre-existing chronic disorders and pregnancy complications increase the risk of CP in offspring. Pre-term delivery plays a significant mediating role in the association between maternal disorders and CP.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Alev Basaran, Zehra Kilinc, Hidir Sari, Ercan Gunduz
Summary: This study aimed to evaluate the etiological risk factors of cerebral palsy, with a focus on preventable factors. Face-to-face interviews were conducted with the mothers of 210 children with cerebral palsy registered at the Mardin Guidance and Research Center. The findings revealed that most of the children were premature, had low birth weight, had parents who were relatives, had mothers with low education level, and came from families with low socioeconomic status. These risk factors, which were largely preventable, were significant.
Article
Public, Environmental & Occupational Health
Ruoqing Chen, Arvid Sjolander, Stefan Johansson, Donghao Lu, Neda Razaz, Kristina Tedroff, Eduardo Villamor, Sven Cnattingius
Summary: The study revealed an inverse dose-response relationship between gestational age and risk of CP, with neurological-related neonatal diseases being the main mediator of CP risk. As gestational age increases, the proportion of CP risk mediated by neonatal morbidity decreases.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Clinical Neurology
Andrew T. Hale, Oluwatoyin Akinnusotu, Jing He, Janey Wang, Natalie Hibshman, Chevis N. Shannon, Robert P. Naftel
Summary: This study is the first genome-wide association study of spastic CP, identifying a SNP (rs78686911) associated with CP by decreasing expression of GRIK4. The findings suggest that genetic variation contributes to the risk of CP.
Article
Medicine, General & Internal
Michael G. Ross
Summary: Cases involving cerebral palsy litigation are often focused on obstetricians/gynecologists, who face high liability in medical professions. Despite only a small proportion of cerebral palsy cases being caused by birth asphyxia, negligent obstetrical care is often blamed as the etiological factor.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pediatrics
Laura A. Prosser, Julie Skorup, Samuel R. Pierce, Abbas F. Jawad, Andrew H. Fagg, Thubi H. A. Kolobe, Beth A. Smith
Summary: This project aims to understand how infants at high risk for cerebral palsy (CP) learn to move and acquire early locomotor skills over the first 18 months of life. Robotic and sensor technology will be used for intervention and longitudinal study of infant movement during early spontaneous movement, prone locomotion (crawling), and upright locomotion (walking) stages. The study will enroll sixty participants and collect data on locomotor skill, training characteristics, and variables related to locomotor learning. The findings will contribute to the development of predictive models for locomotor skill acquisition in infants at high risk for CP.
FRONTIERS IN PEDIATRICS
(2023)
Article
Pediatrics
Chiara Guadagno, Francesco Cavallin, Luca Brasili, Donald Micah Maziku, Dionis Erasto Leluko, Gaetano Azzimonti, Giovanni Putoto, Andrea Pietravalle, Daniele Trevisanuto
Summary: This study investigated the relationship between neonatal temperature at admission and the risk of cerebral palsy at one month of age in a low-resource setting. The results showed a non-linear relationship between admission temperature and moderate/high risk of cerebral palsy at one month of age.
Article
Neurosciences
Malgorzata Sadowska, Beata Sarecka-Hujar, Ilona Kopyta
Summary: This study analyzed 181 children with cerebral palsy and found that respiratory failure, infections, intraventricular bleeding, and prematurity were the most common risk factors. Factors such as duration of pregnancy and preterm contractions significantly differentiated subgroups of patients depending on the type of cerebral palsy. Additionally, most perinatal, neonatal, and infant-related risk factors differed significantly between cerebral palsy types, with intraventricular bleeding being an independent predictor for tetraplegic cerebral palsy type.
Article
Clinical Neurology
Anna-Lisa Sorg, Rudiger Von Kries, Mathias Klemme, Lucia Gerstl, Andreas Beyerlein, Nicholas Lack, Ursula Felderhoff-Muser, Mark Dzietko
Summary: The study found that the incidence of neonatal CSVT in term and preterm infants falls within the range of other population-based studies, and suggests that hypoxia is an important perinatal risk factor for the etiology of neonatal CSVT.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2021)
Article
Clinical Neurology
Alexander Humberg, Mark Dzietko, Soeren Schulz, Ursula Felderhoff-Mueser, Britta Huening, Anja Stein, Mats Fortmann, Janina Marissen, Tanja K. Rausch, Egbert Herting, Christoph Haertel, Wolfgang Goepel
Summary: Carriers of the APOE-epsilon 4 genotype have an increased risk of long-term motor deficits after intracerebral hemorrhage (ICH) in preterm infants.
Article
Clinical Neurology
Fabiola Barron-Garza, Mario Coronado-Garza, Sixto Gutierrez-Ramirez, Jose-Manuel Ramos-Rincon, Francisco Guzman-de la Garza, Alexia Lozano-Morantes, Anahi Flores-Rodriguez, Adriana Nieto-Sanjuanero, Neri Alvarez-Villalobos, Maribel Flores-Villarreal, Luz Covarrubias-Contreras
Summary: This study aimed to assess the incidence of cerebral palsy in children aged up to 18 months in northeast Mexico and analyze the risk factors and neuroimaging findings. The study found a relatively high incidence of cerebral palsy, which was associated with nonprogressive lesions of the central nervous system during fetal or infant brain development. Perinatal risk factors, such as brain hemorrhage, prematurity, and congenital anomalies, were predominantly recognized in the etiology of cerebral palsy.
PEDIATRIC NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Maiya Zhakupova, Ardak Nurbakyt, Dinara Ospanova, Ardak Chuyenbekova, Zhanat Kozhekenova, Gauhar Dauletova, Akmaral Aitmanbetova, Maksat Abdikadir, Zhilvinas Padaiga, Marina Izmailovich, Natalya Glushkova, Yuliya Semenova
Summary: This epidemiological study aimed to fill the knowledge gap on the incidence and underlying risk factors of cerebral palsy (CP) in the Republic of Kazakhstan. The national CP incidence showed mild variability, ranging from 68.7 to 83.3 per 100,000 population. Maternal risk factors associated with CP included arterial hypertension, thrombocytopenia, diabetes mellitus, pathology of fetal membranes, premature rupture of membranes, and acute respiratory illness during pregnancy. Low Apgar score, gestational age, birth weight, and the presence of intraventricular hemorrhage or periventricular leukomalacia were important neonatal risk factors.
Article
Obstetrics & Gynecology
Roberta Pineda, Lara Liszka, Pido Tran, Jenny Kwon, Terrie Inder
Summary: The study found that very preterm infants with low medical risk at term equivalent age showed more sub-optimal reflexes and stress, as well as poorer performance on neurologic assessments compared to full-term infants.
JOURNAL OF PERINATOLOGY
(2022)
Article
Clinical Neurology
Damjan Osredkar, Ivan Verdenik, Anja Troha Gergeli, Ksenija Gersak, Miha Lucovnik
Summary: This study found that a low 5-minute Apgar score in preterm infants was significantly associated with increased risk of death or cerebral palsy. However, in surviving preterm infants at gestational age over 32 weeks, a low 5-minute Apgar score was specifically associated with cerebral palsy.
Article
Medicine, Research & Experimental
Dorota Sienkiewicz, Grazyna Paszko-Patej, Bozena Okurowska-Zawada, Wojciech Kulak
ARCHIVES OF MEDICAL RESEARCH
(2018)
Article
Clinical Neurology
Anna Mirska, Wojciech Kulak, Bozena Okurowska-Zawada, Elzbieta Dmitruk
CHILDS NERVOUS SYSTEM
(2019)
Article
Biotechnology & Applied Microbiology
Dorota Sienkiewicz, Wojciech Kulak, Grazyna Paszko-Patej, Bozena Okurowska-Zawada, Jerzy Sienkiewicz, Piotr Kulak
BIOMED RESEARCH INTERNATIONAL
(2019)
Article
Psychiatry
Mateusz Cybulski, Lukasz Cybulski, Elzbieta Krajewska-Kulak, Magda Orzechowska, Urszula Cwalina, Beata Kowalewska
ANNALS OF GENERAL PSYCHIATRY
(2020)
Article
Dermatology
Beata Kowalewska, Mateusz Cybulski, Barbara Jankowiak, Elzbieta Krajewska-Kulak
DERMATOLOGY AND THERAPY
(2020)
Article
Environmental Sciences
Elzbieta Krajewska-Kulak, Mateusz Cybulski, Paulina Anisko, Magda Poplawska
Summary: The study found that both young people and older adults generally have negative attitudes towards seniors, with average life satisfaction and lower self-esteem in seniors. There is a significant correlation between life satisfaction and self-esteem in seniors, and gender, age, education, or place of residence did not impact negative attitudes in both groups.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Mariusz Celinski, Mateusz Cybulski, Joanna Filon, Marta Muszalik, Mariusz Goniewicz, Elzbieta Krajewska-Kulak, Anna Slifirczyk
Summary: This study aimed to analyze medical emergency interventions in geriatric patients in the Biala Podlaska and Chelm (Poland) region. The research found that the majority of interventions took place at the patient's home, with an average stay at the scene of 20 minutes. The highest number of interventions occurred between 8:00 p.m. and 8:59 p.m.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Geriatrics & Gerontology
Katarzyna Van Damme-Ostapowicz, Mateusz Cybulski, Monika Galczyk, Elzbieta Krajewska-Kulak, Marek Sobolewski, Anna Zalewska
Summary: The study found that participants were generally satisfied with their lives, with men rating their satisfaction higher than women. As the level of depression increased, life satisfaction decreased. Significant correlations were found between the various measures of depression considered in the study, indicating that these tools can be used in parallel.
Article
Medicine, General & Internal
Mateusz Cybulski, Urszula Cwalina, Dorota Sadowska, Elzbieta Krajewska-Kulak
Summary: The study found that older participants in the Universities of the Third Age in Poland generally displayed mild symptoms of anxiety. Significant differences were observed between women and men in terms of STAI X-1 and STAI X-2 scores. Single respondents and divorced respondents also showed significant differences in STAI X-1 scores. Additionally, respondents with average financial status differed significantly from those with good financial status in various scoring aspects.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Environmental Sciences
Mariusz Celinski, Mateusz Cybulski, Joanna Filon, Marta Muszalik, Mariusz Goniewicz, Elzbieta Krajewska-Kulak, Anna Slifirczyk
Summary: This study analyzed medical management in geriatric patients in Hospital Emergency Departments in Poland between 2016 and 2018, with cardiovascular diseases being the most common diagnosis. The majority of patients were transported to hospitals by ambulance, and some received further in-patient treatment in the department.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Magda Orzechowska, Mateusz Cybulski, Elzbieta Krajewska-Kulak, Marek Sobolewski, Agnieszka Gniadek, Wiaczeslaw Niczyporuk
Summary: This study conducted a comparative analysis of sexually transmitted viral infections in Poland from 2010 to 2015, taking into account the country's administrative division. It found a declining trend in the incidence of genital herpes, with genital warts being the most frequent infection. The incidence of newly detected HIV infections appeared to be stable. The study also observed a correlation between the incidence rates and urbanization.
JOURNAL OF CLINICAL MEDICINE
(2022)
