Pd-Catalyzed Decarboxylative Asymmetric Protonation of Sterically Hindered α-Aryl Lactones and Dihydrocoumarins

Enantioselective Synthesis of Sterically Hindered Tertiary α-Aryl Oxindoles via Palladium-Catalyzed Decarboxylative Protonation. An Experimental and Theoretical Mechanistic Investigation

(2018) Maria Biosca et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives

(2017) Jing-Hai Jin et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Catalyzed [4 + 2] Cyclization of Saturated Carboxylic Acid with o-Quinone Methides through in Situ Activation: Enantioselective Synthesis of Dihydrocoumarins

(2017) Yuanfeng Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantiodivergent Synthesis of Tertiary α-Aryl 1-Indanones: Evidence Toward Disparate Mechanisms in the Palladium-Catalyzed Decarboxylative Asymmetric Protonation

(2017) Cian Kingston et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective synthesis of sterically hindered α-allyl–α-aryl oxindoles via palladium-catalysed decarboxylative asymmetric allylic alkylation

(2017) Mark Jackson et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Carbene and Acid Cooperative Catalytic Reactions of Aldehydes and o-Hydroxybenzhydryl Amines for Highly Enantioselective Access to Dihydrocoumarins

(2017) Xingkuan Chen et al.   ORGANIC LETTERS

Iridium-catalyzed asymmetric hydrogenation of racemic α-substituted lactones to chiral diols

(2017) Xiao-Hui Yang et al.   Chemical Science

Highly Enantioselective Construction of Sterically Hindered α-Allyl-α-Aryl Lactones via Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation

(2017) Jinju James et al.   ACS Catalysis

Conjugate addition–enantioselective protonation reactions

(2016) James P Phelan et al.   Beilstein Journal of Organic Chemistry

Highly Enantioselective Formation of α-Allyl-α-Arylcyclopentanones via Pd-Catalysed Decarboxylative Asymmetric Allylic Alkylation

(2016) Ramulu Akula et al.   CHEMISTRY-A EUROPEAN JOURNAL

Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light

(2016) Megan A. Emmanuel et al.   NATURE

Enantioselective Synthesis of α-Allyl-α-aryldihydrocoumarins and 3-Isochromanones via Pd-Catalyzed Decarboxylative Asymmetric Allylic Alkylation

(2016) Ramulu Akula et al.   ORGANIC LETTERS

Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules

(2015) Yiyang Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

(2015) Anna Lee et al.   CHEMICAL COMMUNICATIONS

The use of the lactone motif in chemical communication

(2015) Stefan Schulz et al.   NATURAL PRODUCT REPORTS

Antioxidant and antitumor activities of 4-arylcoumarins and 4-aryl-3,4-dihydrocoumarins

(2014) Keyun Zhang et al.   BIOCHIMIE

A Stereoselective Switch: Enantiodivergent Approach to the Synthesis of Isoflavanones

(2014) Robert Doran et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Synthesis of Sterically Hindered Tertiary α-Aryl Ketones

(2014) Robert Doran et al.   JOURNAL OF ORGANIC CHEMISTRY

All-Carbon Quaternary Stereogenic Centers in Acyclic Systems through the Creation of Several C–C Bonds per Chemical Step

(2014) Ilan Marek et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

Catalytic Asymmetric Assembly of C3-Monosubstituted Chiral Carbazolones and Concise Formal Synthesis of (−)-Aspidofractinine: Application of Enantioselective Pd-Catalyzed Decarboxylative Protonation of Carbazolones

(2014) Ruirui Zhao et al.   ORGANIC LETTERS

Amino alcohol-mediated enantioselective syntheses of α-substituted indanones and tetralones, ammonium enolates as key intermediates

(2014) Jacques Muzart   TETRAHEDRON-ASYMMETRY

Weak Arene CH⋅⋅⋅O Hydrogen Bonding in Palladium-Catalyzed Arylation and Vinylation of Lactones

(2013) Zhiyan Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts

(2013) Jing Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis

(2013) Allen Y. Hong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective construction of sterically hindered tertiary α-aryl ketones: a catalytic asymmetric synthesis of isoflavanones

(2012) Michael P. Carroll et al.   CHEMICAL COMMUNICATIONS

Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals

(2012) Ji-Woong Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd2(dba)3 as a Precursor of Soluble Metal Complexes and Nanoparticles: Determination of Palladium Active Species for Catalysis and Synthesis

(2012) Sergey S. Zalesskiy et al.   ORGANOMETALLICS

Synthesis and biological evaluation of hydroxylated 3-phenylcoumarins as antioxidants and antiproliferative agents

(2011) Jie Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Enantioselective α-Arylation of Carbonyls via Cu(I)-Bisoxazoline Catalysis

(2011) James S. Harvey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective α-Arylation ofN-Acyloxazolidinones with Copper(II)-bisoxazoline Catalysts and Diaryliodonium Salts

(2011) Aurélien Bigot et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric α-Arylation and Heteroarylation of Ketones with Chloroarenes: Effect of Halide on Selectivity, Oxidation State, and Room-Temperature Reactions

(2011) Shaozhong Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-Catalyzed α-Arylation of Carbonyl and Related Molecules: Novel Trends in CC Bond Formation by CH Bond Functionalization

(2010) Carin C. C. Johansson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Asymmetric Allylic Alkylation of 2-Acylimidazoles as Ester Enolate Equivalents

(2010) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A palladium-catalysed enolate alkylation cascade for the formation of adjacent quaternary and tertiary stereocentres

(2010) Jan Streuff et al.   Nature Chemistry

Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides

(2009) Fabio Bellina et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of Enol Carbonates

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Enantioselective α-Arylation and α-Vinylation of Oxindoles Facilitated by an Axially Chiral P-Stereogenic Ligand

(2009) Alexander M. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective α-Arylation of Carbonyl Compounds

(2009) Antonio Burtoloso   SYNLETT

Asymmetric Malonic and Acetoacetic Acid Syntheses - A Century of Enantioselective Decarboxylative Protonations

(2008) Jérôme Blanchet et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Cycloadditions ofo-Quinone Methides Employing Chiral Ammonium Fluoride Precatalysts

(2008) Ethan Alden-Danforth et al.   ORGANIC LETTERS

Homogeneous Pd-Catalyzed Enantioselective Decarboxylative Protonation

(2008) Smaranda C. Marinescu et al.   ORGANIC LETTERS

Enantioselective α-Arylation of Ketones with Aryl Triflates Catalyzed by Difluorphos Complexes of Palladium and Nickel

(2007) Xuebin Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY