4.7 Article

An Efficient Tetrabutylammonium Fluoride (TBAF)-Catalyzed Three-Component Synthesis of 3-Substituted Indole Derivatives under Solvent-Free Conditions

期刊

ADVANCED SYNTHESIS & CATALYSIS
卷 355, 期 9, 页码 1840-1848

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201300162

关键词

green chemistry; multicomponent reactions; nitrogen heterocycles; synthetic methods

资金

  1. Council of Scientific and Industrial Research (CSIR), New Delhi
  2. Department of Biotechnology (DBT), New Delhi

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An expedient and efficient one-pot three-component synthesis of 3-substituted indoles has been developed by the reaction of indoles, active methylene compounds and aldehydes using a catalytic amount of tetrabutylammonium fluoride under solvent-free conditions.

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