Structural and Catalytic Characterization of Pichia stipitis OYE 2.6, a Useful Biocatalyst for Asymmetric Alkene Reductions

A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity

(2011) Helen S. Toogood et al.   CHEMBIOCHEM

Enantioenriched Compounds via Enzyme-Catalyzed Redox Reactions

(2011) Mélanie Hall et al.   CHEMICAL REVIEWS

Biocatalyzed Enantioselective Reduction of Activated C=C Bonds: Synthesis of Enantiomerically Enriched α-Halo-β-arylpropionic Acids

(2011) Elisabetta Brenna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Chiral Rhodium Complexes Derived From Electron-Rich Phosphine-Phosphites as Asymmetric Hydrogenation Catalysts

(2011) Pablo Etayo et al.   ORGANOMETALLICS

Biocatalytic Reductions of Baylis–Hillman Adducts

(2011) Adam Z. Walton et al.   ACS Catalysis

Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins

(2011) Anna Fryszkowska et al.   Catalysis Science & Technology

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Asymmetric Synthesis of (R)-3-Hydroxy-2-methylpropanoate (‘Roche Ester’) and Derivatives via Biocatalytic CC-Bond Reduction

(2010) Clemens Stueckler et al.   ADVANCED SYNTHESIS & CATALYSIS

Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries

(2010) Martyn E. Hulley et al.   CHEMBIOCHEM

Biocatalytic Reductions and Chemical Versatility of the Old Yellow Enzyme Family of Flavoprotein Oxidoreductases

(2010) Helen S. Toogood et al.   ChemCatChem

Towards preparative-scale, biocatalytic alkene reductions

(2010) Despina J. Bougioukou et al.   CHEMICAL COMMUNICATIONS

Asymmetric Hydrogenation with Highly Active IndolPhos-Rh Catalysts: Kinetics and Reaction Mechanism

(2010) Jeroen Wassenaar et al.   CHEMISTRY-A EUROPEAN JOURNAL

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Directed Evolution of an Enantioselective Enoate-Reductase: Testing the Utility of Iterative Saturation Mutagenesis

(2009) Despina J. Bougioukou et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic α-hydroxymethylation of cyclopentanone with aqueous formaldehyde: Easy access to chiral δ-lactones

(2009) Nobuyuki Mase et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biocatalysis with Thermostable Enzymes: Structure and Properties of a Thermophilic ‘ene’-Reductase related to Old Yellow Enzyme

(2009) Björn V. Adalbjörnsson et al.   CHEMBIOCHEM

Site-Saturation Mutagenesis of Tryptophan 116 of Saccharomyces pastorianus Old Yellow Enzyme Uncovers Stereocomplementary Variants

(2009) Santosh Kumar Padhi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

l-Threonine-catalysed asymmetric α-hydroxymethylation of cyclohexanone: application to the synthesis of pharmaceutical compounds and natural products

(2009) Anqi Chen et al.   TETRAHEDRON

Convenient General Asymmetric Synthesis of Roche Ester Derivatives through Catalytic Asymmetric Hydrogenation: Steric and Electronic Effects of Ligands

(2008) Cyrielle Pautigny et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantiocomplementary Enzymes: Classification, Molecular Basis for Their Enantiopreference, and Prospects for Mirror-Image Biotransformations

(2008) Paul F. Mugford et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Saturation mutagenesis of putative catalytic residues of benzoylformate decarboxylase provides a challenge to the accepted mechanism

(2008) A. Yep et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA