期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 353, 期 13, 页码 2363-2367出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201100403
关键词
aqueous media; biocatalysis; esters; olefin metathesis; one-pot synthesis
资金
- Graduate School of Molecular Science at the University of Erlangen-Nurnberg
- Fonds der Chemischen Industrie
A new synthetic method for the preparation of cyclic malonic acid monoesters in aqueous media was developed based on the combination of a metathesis reaction and subsequent biocatalytic hydrolysis with a pig liver esterase in a one-pot synthesis. Both reaction steps proceed smoothly under optimized conditions in aqueous media requiring only a low amount of the metal catalyst for the metathesis reaction. Notably, the applied biocatalyst turned out to be highly compatible with the metal catalyst showing no significant influence on the enzyme activity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据