期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 352, 期 13, 页码 2195-2199出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000322
关键词
alkylations; arenes; Birch reductions; reaction mechanisms; synthetic methods
Terephthalic acid reacts with alkyl halides under Birch conditions to substituted 1,4-cyclohexadienes in high yields and good stereoselectivities. Electrophiles containing ester or nitrile groups undergo a surprising fragmentation under the reaction conditions. Subsequent treatment with chlorosulfonic acid proceeds by an interesting tandem decarbonylation/decarboxylation, affording 1,4-dialkylbenzenes in excellent regioselectivity. Thus our new method is superior to classical Friedel-Crafts alkylations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据