Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

(2018) Shuangjiang Yu et al.   ADVANCED MATERIALS

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy

(2018) Keman Cheng et al.   NANO LETTERS

Acidity-Triggered Ligand-Presenting Nanoparticles To Overcome Sequential Drug Delivery Barriers to Tumors

(2017) Tingting Wang et al.   NANO LETTERS

Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression

(2017) Jianqin Lu et al.   Nature Communications

Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

(2017) Guangbao Yang et al.   Nature Communications

Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?

(2017) Andrew L. Mellor et al.   Frontiers in Immunology

Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors

(2016) Yanqi Ye et al.   ACS Nano

Versatile Prodrug Nanoparticles for Acid-Triggered Precise Imaging and Organelle-Specific Combination Cancer Therapy

(2016) Bing Feng et al.   ADVANCED FUNCTIONAL MATERIALS

An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

(2016) Yichao Chen et al.   Nature Communications

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy

(2015) L. Zhai et al.   CLINICAL CANCER RESEARCH

A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy

(2015) Samuel G. Awuah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

(2015) Shabnam Shalapour et al.   NATURE

IDO inhibitors move center stage in immuno-oncology

(2015) Cormac Sheridan   NATURE BIOTECHNOLOGY

Big opportunities for small molecules in immuno-oncology

(2015) Jerry L. Adams et al.   NATURE REVIEWS DRUG DISCOVERY

A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells

(2015) B. M. Carreno et al.   SCIENCE

Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner

(2015) Rikke B. Holmgaard et al.   Cell Reports

Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines

(2014) Yongjun Wang et al.   NANO LETTERS

Rational Design of Polyion Complex Nanoparticles to Overcome Cisplatin Resistance in Cancer Therapy

(2013) Xian-Zhu Yang et al.   ADVANCED MATERIALS

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

(2010) X. Liu et al.   BLOOD

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE