Review
Nanoscience & Nanotechnology
Xu Qin, Wangyu Sun, Ziheng Zhou, Pengyu Fu, Hao Li, Yue Li
Summary: The review focuses on the technique of waveguide effective plasmonics, which provides a feasible low-loss realization of plasmonic metamaterials in lower frequency based on the structural dispersion. It highlights the underlying physics of waveguide effective plasmonics and its applications, ranging from classical plasmonic concepts to novel effective plasmonic devices. Additionally, it briefly discusses the future research directions and potential applications.
Article
Nanoscience & Nanotechnology
Nikolai B. Chichkov, Andrey B. Evlyukhin, Boris N. Chichkov
Summary: The letter evaluates the rest mass of light-induced surface-plasmon polaritons (SPPs) and discusses the idea of collisions between two massive SPP quasiparticles resulting in frequency changes according to energy and momentum conservation laws.
Article
Chemistry, Multidisciplinary
Shahab Razavi, Yiping Zhao
Summary: This study demonstrates that a hybridized plasmonic mode in a compound nanohole structure can be described as a quasi-dipole oscillator. By introducing two nanorods into a nanohole, these two quasi-dipoles can couple and hybridize, resulting in additional transmission peaks. The intensities and separations of these peaks can be controlled by adjusting the incident polarization and modifying the nanorod length. This concept can be extended to predict the behavior of more complex compound configurations, allowing for precise engineering of transmission peaks.
Article
Nanoscience & Nanotechnology
Bryson Krause, Minh T. Pham, Hoang M. Luong, Tho D. Nguyen, Thang B. Hoang
Summary: Nanohole arrays can enhance the lasing emission of organic dye liquid gain medium and accelerate the decay rate of CdSe quantum dots. They are simple to fabricate, exhibit excellent optical responses, and have great potential in various emerging technologies such as gas sensing, biomedical imaging, and ultrafast on-chip coherent light sources.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Emilija Petronijevic, Ramin Ghahri, Concita Sibilia
Summary: This study introduces a method of coupling emitting layers with plasmonic elliptical nanohole arrays to achieve circularly dependent near-infrared and visible emission, showcasing the chiral absorption and emission properties of the design.
APPLIED SCIENCES-BASEL
(2021)
Article
Nanoscience & Nanotechnology
Bryson Krause, Minh T. Pham, Hoang M. Luong, Tho D. Nguyen, Thang B. Hoang
Summary: Periodic arrays of air nanoholes in thin metal films can enhance light-matter interactions at the nanoscale. A simple technique of fabricating hexagonal nanohole arrays is employed, which offers excellent optical responses and can be used for enhanced lasing and spontaneous emission of novel nanomaterials.
ACS APPLIED NANO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Xu Qin, Yijing He, Wangyu Sun, Pengyu Fu, Shuyu Wang, Ziheng Zhou, Yue Li
Summary: This study investigates the concept of stepped waveguide metamaterials as low-loss effective replicas of surface plasmon polaritons (SPPs). The proposed structure maintains the same field configuration as regular SPPs but avoids inherent losses, outperforming regular low-loss SPP designs with natural plasmonic materials in terms of propagation lengths. Furthermore, the stepped waveguide metamaterial exhibits excellent compatibility in direct interconnections with arbitrary regular SPPs, potentially leading to new SPP devices with low-loss advantages.
Article
Engineering, Electrical & Electronic
Nada AbdElaziz, Bedir Yousif, Eman AbdElhalim, Waleed M. Gaballah, Ahmed S. Samra
Summary: The photonics world is increasingly interested in plasmonic photodetectors, as they allow light to be confined to small spaces in metallic structures, leading to improved performance. In this study, a GaAs PIN photodetector with gold and aluminum surface plasmon polariton (SPP) rectangle grating achieved a higher internal quantum efficiency (IQE) compared to a standard GaAs photodetector without SPP grating. Nanogratings of various shapes were also studied, with the bowtie shape showing the most significant enhancement in IQE. This research highlights the potential of plasmonic photodetectors for enhancing light absorption and generation in semiconductor materials.
OPTICAL AND QUANTUM ELECTRONICS
(2023)
Article
Nanoscience & Nanotechnology
S. Ali Hassani Gangaraj, Francesco Monticone
Summary: Investigated a method to break reciprocity without relying on magneto-optical effects or spacetime modulations by biasing a plasmonic material with a direct electric current. Explored the propagation properties of surface plasmon-polaritons (SPPs) supported by this nonreciprocal platform and discovered previously overlooked anomalous wave-propagation effects. Clarified the impact of dissipation on nonreciprocal effects and revealed connections between inflection points, exceptional points at band-edges, and complex modal transitions. Theoretical demonstration of drift-induced nonreciprocal near-field radiative heat transfer in the field of thermal photonics.
Article
Crystallography
Kaixiang Sun, Jiukai Fang, Yanpeng Shi, Shengnan Shi, Shan Zhang, Jinmei Song, Meiping Li, Xiaodong Wang, Fuhua Yang
Summary: This paper presents a structure for refractive index sensors in the terahertz band, utilizing enhanced extraordinary optical transmission to generate strong local electromagnetic field for sensing. Depending on the sensing position, the sensitivity can vary, with the highest being 51.56 GHz/RIU based on Mie scattering and the lowest being 5.13 GHz/RIU based on surface plasmon polaritons. The sensor is also capable of detecting the thickness of the analyte, with a minimum detectable height of 0.2 μm.
Article
Engineering, Electrical & Electronic
Gaurav Mittal, Nagendra Prasad Pathak
Summary: This article presents the study and application of spoof surface plasmon polaritons (SSPPs) in the microwave frequency domain, controlling the dispersion relation and designing a broadband bandpass filter (BPF) using plasmonic metamaterial. Experimental results show that the passband of the BPF is 1.2 to 6.0 GHz with an insertion loss less than 2 dB.
MICROWAVE AND OPTICAL TECHNOLOGY LETTERS
(2021)
Article
Nanoscience & Nanotechnology
Ruth F. Balderas-Valadez, Claudia Pacholski
Summary: By combining two porous materials, namely porous silicon and plasmonic nanohole arrays, the hybrid sensor achieves increased sensitivity and dual-mode sensing capabilities. The combination of porous silicon and plasmonic nanohole arrays results in higher reflectance and improved sensitivity, making it suitable for high-sensitivity sensing applications. The hybrid sensor demonstrates significant enhancement in sensitivity and ability to perform simultaneous and independent dual-mode sensing.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Electrical & Electronic
Anjali Yadav, Shailendra K. Varshney, Basudev Lahiri
Summary: This study proposes the design of silver gratings filled with anisotropic Molybdenum Trioxide (alpha-MoO3) to exhibit extraordinary transmission (EOT) by utilizing phonon polaritons (PhPs). The tunability of EOT is numerically demonstrated by introducing a layer of graphene nanoribbon in the proposed device, which can be used as a mid-infrared switch. The reported work has potential importance in diverse applications.
IEEE PHOTONICS JOURNAL
(2022)
Article
Biochemical Research Methods
Charles Soon Hong Hwang, Myeong-Su Ahn, Ki-Hun Jeong
Summary: Silver-gold alloy nanohole arrays demonstrate enhanced refractive index sensitivity and long-term stability for ultra-sensitive plasmonic label-free detection of Escherichia coli, providing a new outlook for widely applicable biosensing and bio-medical applications.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Materials Science, Multidisciplinary
Sy-Hann Chen, Wu-Jui Hsieh, Yi-Wen Hong, Hung Ji Huang, Li-Ming Chiang, Tsung Sheng Kao, Min-Hsiung Shih, Hai-Pang Chiang
Summary: This study introduces a novel approach to enhance electromagnetic fields interaction and reduce photoluminescence (PL) lifetime in plasmon-enhanced fluorescence. By fabricating gold (Au) nanohole arrays (ANA) decorated with ring-shaped silver nanoparticles (AgNPs) on a silicon-dioxide (SiO2)/silver (Ag) substrate, the surface plasmon resonance coupling and PL reactions are investigated. The proposed substrate shows a remarkable enhancement of PL intensity and a reduction in PL lifetime. The findings demonstrate the potential of using ANAs decorated with ring-shaped AgNPs in biosensing, imaging, and photonics.
RESULTS IN PHYSICS
(2023)
Article
Nanoscience & Nanotechnology
Marianne Aellen, Aurelio A. Rossinelli, Robert C. Keitel, Raphael Brechbuhler, Felipe Antolinez, Sergio G. Rodrigo, Jian Cui, David J. Norris
Summary: The researchers studied the effect of gain on the lasing behavior in plasmonic lasers by placing a semiconductor gain layer near a metallic interface. They found that the thickness of the gain layer determines the nature of the lasing mode, and a gap layer with a high refractive index can be advantageous for plasmonic lasing.
Article
Optics
Hector Monin, Aurelian Loirette-Pelous, Eva De Leo, Aurelio A. Rossinelli, Ferry Prins, David J. Norris, Elise Baily, Jean-Paul Hugonin, Benjamin Vest, Jean-Jacques Greffet
Summary: We investigate the light emission of a patterned ensemble of colloidal quantum dots (cQDs) through experimental and theoretical study. Compared to a planar layer of cQDs, this system significantly modifies the emission spectrum and polarization. It demonstrates bright, directional, and polarized emission, including circular polarization in certain directions. We propose a light emission model based on a local Kirchhoff law, which accurately reproduces all experimental features. This model provides a quantitative figure of merit for assessing the emitted power. This work facilitates the systematic design of efficient ultrathin light emitting metasurfaces with controlled polarization, spectrum, and directivity.
Article
Nanoscience & Nanotechnology
Carin R. Lightner, Filip Desmet, Daniel Gisler, Stefan A. Meyer, Ariel Francis Perez Mellor, Hannah Niese, Arnulf Rosspeintner, Robert C. Keitel, Thomas Burgi, Wouter A. Herrebout, Christian Johannessen, David J. Norris
Summary: Spectroscopic techniques can provide information about the chiral structure of molecules, but small errors in optical polarization control can lead to experimental artifacts. This study focuses on Raman optical activity (ROA) as an example and comprehensively investigates chiroptical artifacts. Based on the findings, standard controls are proposed to help researchers better understand, identify, and avoid experimental artifacts.
Article
Chemistry, Multidisciplinary
Mi Ho Jeong, Taehwang Son, Yoo Keung Tae, Chan Hee Park, Hee Seung Lee, Moon Jae Chung, Jeong Youp Park, Cesar M. M. Castro, Ralph Weissleder, Jung Hyun Jo, Seungmin Bang, Hyungsoon Im
Summary: Cholangiocarcinoma (CCA) is a fatal disease often diagnosed at advanced stages. There is a lack of effective diagnostic methods or biomarkers for early detection of CCA. A nanoplasmonic sensing technology called FLEX is developed for sensitive and robust single extracellular vesicle (EV) analysis, which detected a wide heterogeneity of CCA-derived EVs and identified tumor markers in clinical bile samples. The FLEX assay showed better diagnostic performance than current clinical markers, offering a potential tool for early CCA diagnosis.
Article
Materials Science, Multidisciplinary
Mi Ho Jeong, Hyungsoon Im, Joanna B. Dahl
Summary: In preparation for the use of extracellular vesicles (EVs) in disease diagnostics and therapeutics, researchers are studying the biological, chemical, and physical properties of EVs. Most studies have focused on nanoscale EVs and their biochemical content, while less is known about the characteristics and mechanical properties of larger microscale EVs. A recent pilot study introduced a non-contact microfluidic technique to measure the stiffness of large EVs (>1 μm diameter). By comparing the stiffness distributions of large EVs derived from glioblastoma cell lines, the study found that EVs from cells with the IDH1 mutation, which disrupts lipid metabolism, were stiffer than those from wild-type cells. Lipidomics analysis supported this finding by showing an increase in saturated lipids in EVs with the IDH1 mutation. These findings suggest that high-throughput microfluidics could be used to distinguish between large EV populations with different biomolecular compositions, contributing to a better understanding of EV biomechanics, particularly microscale EVs.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Multidisciplinary
Lip Ket Chin, Jun-Yeong Yang, Benjamin Chousterman, Sunghoon Jung, Do-Geun Kim, Dong-Ho Kim, Seunghun Lee, Cesar M. Castro, Ralph Weissleder, Sung-Gyu Park, Hyungsoon Im
Summary: In this study, an ultrasensitive multiplexed plasmonic sensing technology was developed for rapid quantification of multiple biomarkers in point-of-care settings, which could improve the diagnosis and management of sepsis. The technology integrated chemifluorescence signal enhancement with plasmon-enhanced fluorescence detection, allowing for rapid analysis of cytokine biomarkers with high sensitivity. A plasmonic sensing chip based on nanoparticle-spiked gold nanodimple structures was also developed for direct detection of cytokines in clinical plasma samples.
Article
Biophysics
Iris Baffour Ansah, Matthew Leming, Soo Hyun Lee, Jun-Yeong Yang, ChaeWon Mun, Kyungseob Noh, Timothy An, Seunghun Lee, Dong-Ho Kim, Meehyein Kim, Hyungsoon Im, Sung-Gyu Park
Summary: Seasonal outbreaks of respiratory viral infections are a global concern, and timely and accurate responses are needed due to similar symptoms and subclinical infections. Reliable diagnostic assays are crucial for early infection diagnosis. In this study, a method using surface-enhanced Raman spectroscopy (SERS) and machine learning (ML) analysis was developed to specifically identify different viruses. The method showed high accuracy in identifying eight virus species and demonstrated feasibility for on-site multiplex detection.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Multidisciplinary Sciences
Matthew Leming, Sudeshna Das, Hyungsoon Im
Summary: In this work, a novel deep learning architecture called MUCRAN is introduced to train a deep learning model on clinical brain MRI while addressing demographic and technical confounding factors. MUCRAN is trained using a large clinical dataset and successfully regresses major confounding factors. The combination of MUCRAN and an uncertainty quantification method leads to increased accuracy in AD detection for both newly collected data and data from other hospitals. MUCRAN offers a generalizable approach for deep-learning-based disease detection in heterogeneous clinical data.
Article
Chemistry, Multidisciplinary
Jae-Sang Hong, Taehwang Son, Cesar M. M. Castro, Hyungsoon Im
Summary: The authors present an amplification-free and extraction-free method for detecting extracellular vesicles (EVs) miRNA using a CRISPR/Cas13a sensing system. They encapsulate CRISPR/Cas13a sensing components in liposomes and deliver them into EVs through liposome-EV fusion. By quantifying specific miRNA-positive EV counts in 1 x 10(8) EVs, they demonstrate that miR-21-5p-positive EV counts are significantly higher in ovarian cancer EVs compared to benign cells. They also show the potential for multiplexed protein-miRNA analysis in tumor-derived EVs using this method.
Article
Biophysics
Tae Joon Kwak, Taehwang Son, Jae-Sang Hong, Ursula Andrea Winter, Mi Ho Jeong, Charlotte Mclean, Ralph Weissleder, Hakho Lee, Cesar M. Castro, Hyungsoon Im
Summary: Analysis of rare circulating extracellular vesicles (EVs) from early cancers or different types of host cells requires highly sensitive EV sensing technologies. In this study, an advanced plasmonic EV platform with electrokinetically enhanced yields (KeyPLEX) was developed, which overcame the diffusion limitation for specific target EV capture using applied electroosmosis and dielectrophoresis forces. The KeyPLEX system showed significant improvement in detection sensitivity, enabling sensitive detection of rare cancer EVs from human plasma samples within 10 minutes. The KeyPLEX system could be a valuable tool for point-of-care rapid EV analysis.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Applied
Hyungi Kim, Sungmin Lee, Kyung Won Lee, Eun Su Kim, Hyung-Mo Kim, Hyungsoon Im, Hyun C. Yoon, JeongGil Ko, Eunha Kim
Summary: Monitoring blood sugar level is crucial for diabetes management and complication prevention. A paper-based portable assay system is described for accurate monitoring of glucose levels in tears. The system combines enzyme reactions, fluorescence properties perturbation, automated image analysis, and pattern recognition powered by machine-learning algorithms, all in a single assay. The system achieves high accuracy without the need for extra manual steps. The system's small size (20 x 20 mm) is achieved by printing black wax on cellulose paper, melting it with heat, and depositing different fluorescent compounds and glucose oxidase. The system uses two models, a random forest model and an SVM regression model, along with feature engineering techniques for efficient sensor data processing on resource-limited mobile platforms. The random forest approach achieved 96.7% accuracy (0.2 mM intervals) in accurately classifying glucose concentration, while the SVM regression model resulted in an MSE of 0.026 mM.
Article
Chemistry, Multidisciplinary
Kihyeun Kim, Bobin Lee, Jun Hyeok Park, Ji-Ho Park, Ki Joong Lee, Tae Joon Kwak, Taehwang Son, Yong-Beom Shin, Hyungsoon Im, Min-Gon Kim
Summary: We demonstrate a rapid PCR testing kit that integrates a lateral flow paper strip with a nichrome-based thin film heater. By using a paper membrane as a PCR solution container, fast thermocycling can be achieved without a cooler due to the high specific surface area of the membrane where Joule heating is applied. The amplified PCR products can be simultaneously detected on the lateral flow paper strip with the naked eye.
MATERIALS HORIZONS
(2023)
Meeting Abstract
Hematology
Jae-Hyeok Choi, Lip Ket Chin, Bo Mee Woo, Younghoon Song, Min Jeong Seol, Yoontaik Hong, Seunghee Han, Byeong-il Kang, Ai-Qun Liu, Seongsoo Jang, Hidde Ploegh, Hyungsoon Im, Dongyoung Lee
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
Hyungsoon Im, Mi Ho Jeong, Taehwang Son, Jouha Min, Ralph Weissleder, Hakho Lee
Summary: Exosomes, or extracellular vesicles (EVs), are potential cancer biomarkers that can be detected and characterized using nanoplasmonic sensing technologies. These technologies offer great clinical potential for cancer diagnostics and monitoring of treatment response.
Article
Chemistry, Multidisciplinary
Eva De Leo, Aurelio A. Rossinelli, Patricia Marques-Gallego, Lisa V. Poulikakos, David J. Norris, Ferry Prins
Summary: Linear gratings patterned on the surface of cQD thin films enhance the outcoupling of emission, resulting in bright and saturated colors. By adjusting the periodicity and orientation of the gratings, active color tuning of the thin-film emission is achieved.
