Article
Chemistry, Multidisciplinary
Husnu Gerengi, Marina Cabrini, Moses M. Solomon, Ertugrul Kaya, Luca Gritti, Mehmet Lutfi Yola
Summary: Magnesium and its alloys have potential as biomedical implant materials due to their biodegradability and similar properties to human bones. However, their high degradation rate in physiological systems limits their utilization. This study investigated the use of chemical modification to enhance the corrosion resistance of the AZ31 Mg alloy in simulated body fluid. The results showed that the surface treatment significantly improved the corrosion resistance of the alloy.
Article
Engineering, Biomedical
Nan Zhang, Weidan Wang, Xiuzhi Zhang, Krishna C. Nune, Ying Zhao, Na Liu, R. D. K. Misra, Ke Yang, Lili Tan, Jinglong Yan
Summary: The novel Mg-Sr alloy hollow tubular system with autogenous morselized bone filling proves effective in repairing long-bone segmental defects. Coated implants with Sr-P exhibit enhanced bone formation and mineralization compared to Ca-P coated implants after 12 weeks post-implantation, showcasing bioactive properties and exceptional durability for the regeneration of segmental defects.
BIOACTIVE MATERIALS
(2021)
Article
Cell & Tissue Engineering
N. Angrisani, R. Willumeit-Roemer, H. Windhagen, B. Mavila Chathoth, V. Scheper, B. Wiese, H. Helmholz, J. Reifenrath
Summary: The study found that implanting magnesium cylinders had an influence on the subchondral bone quality of osteoarthritic rabbits, increasing bone volume and reducing cartilage lesions. Further evaluations with different time points and alloys will determine if this can alter osteoarthritis progression.
EUROPEAN CELLS & MATERIALS
(2021)
Review
Engineering, Biomedical
Sankaranarayanan Seetharaman, Dhivya Sankaranarayanan, Manoj Gupta
Summary: Biomedical implants are important for repairing or replacing damaged or diseased tissues or organs. The success of implantation depends on factors such as mechanical properties, biocompatibility, and biodegradability of the materials used. Magnesium-based materials have emerged as a promising class of temporary implants due to their remarkable properties. This review article provides a comprehensive overview of the properties, research works, and potential applications of Mg-based implants.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Surgery
Christopher L. Kalmar, Julia Bushold, Anna R. Carlson, Zachary D. Zapatero, Mychajlo S. Kosyk, Jordan W. Swanson, Jesse A. Taylor, Scott P. Bartlett
Summary: This study examined complications of the latest copolymer of resorbable plates for craniofacial reconstruction in pediatric patients. Results showed 7.9% of patients experienced postoperative complications, with the most common being dehiscence, hematoma/seroma, and infection. Radiotherapy was significantly associated with the development of clinical infection, while there were no differences in complications between different fixation methods.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Bruno Luis Graciliano Silva, Julio Cesar Sanchez-Puetate, Felipe Eduardo Pinotti, Camila Chierici Marcantonio, Gabriel Gimenez Pedroso, Elcio Marcantonio Junior, Rosemary Adriana Chierici Marcantonio
Summary: The aim of this study was to evaluate the effect of obesity on the osseointegration of implants with hydrophobic and hydrophilic surfaces. The results showed that obesity does not interfere with the osseointegration of hydrophobic and hydrophilic implants.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2023)
Article
Multidisciplinary Sciences
Dawid Szyba, Robert Kubina, Katarzyna Mlynarek-Zak, Adrian Radon, Aneta Kania, Rafal Babilas
Summary: Calcium-based alloys have attractive properties as mechanical, corrosive, and biocompatible materials, making them promising candidates for biodegradable implants. This study investigated the biocompatibility and corrosion behavior of several calcium alloys with different concentrations of boron and gold. The results showed that the alloy with 2at.% Au exhibited the best corrosion resistance, while the alloy with 3at.% boron had the highest cell viability. These findings suggest that calcium alloys with specific compositions could be potential materials for implantology.
SCIENTIFIC REPORTS
(2022)
Article
Materials Science, Composites
Maojun Li, Xiaoyang Jiang, Ting Su
Summary: This study investigates the surface quality and mechanical behavior of open-hole composite laminates following different machining processes. The results show that the hole geometrical accuracy and mechanical property are significantly affected by the machining methods, while the influence on strain distribution patterns is limited.
POLYMER COMPOSITES
(2022)
Article
Materials Science, Biomaterials
Philipp Brunner, Florian Brumbauer, Eva-Maria Steyskal, Oliver Renk, Annelie-Martina Weinberg, Hartmuth Schroettner, Roland Wuerschum
Summary: The study reveals that high-pressure torsion significantly reduces the corrosion resistance of Mg-0.45wt%Zn-0.45wt%Ca alloy, resulting in the formation of larger open-volume structures during corrosion, possibly related to hydrogen.
BIOMATERIALS SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
R. Saravanan, T. Sathish, V. Vijayan, S. Rajkumar, Shubham Sharma, Changhe Li, Yanbin Zhang, Kamal Sharma, Sayed M. Eldin
Summary: This research aims to improve the machinability performance and optimize the process parameters for biocompatible magnesium implant manufacturing by using a nanofluid of MoS2 nanoparticles suspended in waste coconut oil. The proposed method significantly improves the machinability performance, as evidenced by the reduction in cutting force, feed force, surface roughness, cutting zone temperature, and tool wear.
REVIEWS ON ADVANCED MATERIALS SCIENCE
(2023)
Article
Engineering, Biomedical
Marianne Liebi, Viviane Lutz-Bueno, Manuel Guizar-Sicairos, Bernd M. Schoenbauer, Johannes Eichler, Elisabeth Martinelli, Jorg F. Loffler, Annelie Weinberg, Helga Lichtenegger, Tilman A. Grunewald
Summary: This study investigates the nanostructural adaptation of bone around degrading implants using techniques like SASTT. It reveals that bone nanostructural adaptation starts with rapid interfacial bone growth near the implant and spreads throughout the bone volume in later stages.
ACTA BIOMATERIALIA
(2021)
Article
Engineering, Biomedical
Jonathan Espiritu, Sandra Sefa, Hanna Cwieka, Imke Greving, Silja Flenner, Regine Willumeit-Roemer, Jan-Marten Seitz, Berit Zeller-Plumhoff
Summary: The increasing prevalence of bone-related injuries and aging geriatric populations are driving the growth of the orthopaedic implant market. A hierarchical analysis of bone remodelling after material implantation is necessary to understand the relationship between implant and bone. Osteocytes play a vital role in bone health and remodelling processes, making it essential to examine the lacuno-canalicular network (LCN) in response to implant materials. Biodegradable materials, such as magnesium alloys, offer a potential solution to permanent implants, and surface treatments like plasma electrolytic oxidation (PEO) can slow degradation. This study investigates the impact of PEO-coated WE43 on the LCN using nondestructive 3D imaging, and the findings suggest that slower degradation induced by PEO-coating results in healthier lacunar shapes within the LCN.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Nicole G. Sommer, Daniela Hirzberger, Lisa Paar, Leopold Berger, Hanna Cwieka, Uwe Y. Schwarze, Valentin Herber, Begum Okutan, Andrew J. Bodey, Regine Willumeit-Roemer, Berit Zeller-Plumhoff, Joerg F. Loeffler, Annelie M. Weinberg
Summary: This study investigated the osseointegration and implant degradation of a magnesium-zinc-calcium implant in an ovariectomy-induced osteoporotic rat model. The results showed enhanced implant degradation and sclerotic rim formation in the osteoporotic rats compared to the healthy rats. This study highlights the importance of considering different bone conditions in the development of biodegradable implants.
ACTA BIOMATERIALIA
(2022)
Article
Materials Science, Multidisciplinary
Karollyne Gomes de Castro Monsores, Anderson Oliveira da Silva, Suzane de SantAna Oliveira, Ricardo Ponde Weber, Paulo Feliciano Filho, Sergio Neves Monteiro
Summary: The study investigated the mechanical, structural, and morphological properties of polystyrene under fatigue combined with accelerated aging. It was found that irradiation caused changes in mechanical resistance and properties such as reduced molecular mass and increased crystallinity, influencing the failure mechanism in mechanically fractured specimens.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Engineering, Biomedical
Yaping Zhang, Yuanding Huang, Frank Feyerabend, Carsten Blawert, Weimin Gan, Emad Maawad, Sihang You, Sarkis Gavras, Nico Scharnagl, Julia Bode, Carla Vogt, Daniela Zander, Regine Willumeit-Roemer, Karl Ulrich Kainer, Norbert Hort
Summary: The presence of intermetallic particles in Mg-Nd alloys has two conflicting effects on corrosion: enhancing micro-galvanic corrosion (negative role) and promoting the formation of a continuous and compact corrosion layer (positive role). As the immersion proceeds, the positive role of intermetallic particles becomes more pronounced, ultimately impacting the corrosion rate of the alloys.
ACTA BIOMATERIALIA
(2021)
Article
Automation & Control Systems
Carlos E. H. Ventura, Frederico C. Magalhaes, Alexandre M. Abrao, Berend Denkena, Bernd Breidenstein
Summary: This study investigates the impact of geometric parameters on cutting tool performance when turning hardened steel, finding that parameters such as hone radius projection, form factor, and perimeter ratio have significant effects on cutting force and temperature. The experimental and numerical results provide insights into the relationship between edge preparation and cutting forces, as well as chip temperature trends.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2021)
Article
Engineering, Manufacturing
P. Kuhlemann, B. Denkena, T. Grove
Summary: Current research demonstrates that the mechanical surface-strengthening process of deeprolling is effective in improving the strength and life span of highly stressed components. Adjusting the process temperature during deep-rolling can further increase the mechanical life span, especially in soft machining operations where higher degrees of plastic deformation are induced in the subsurface.
CIRP JOURNAL OF MANUFACTURING SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Industrial
Berend Denkena, Alexander Kroedel, Arne Muecke, Lars Ellersiek
Summary: Surface quality is crucial in 5-axis ball end milling for determining component performance. This paper introduces a new method to predict surface defects, allowing for the selection of suitable process parameters without extensive experimental efforts.
CIRP ANNALS-MANUFACTURING TECHNOLOGY
(2021)
Article
Engineering, Manufacturing
Berend Denkena, Fritz Schinkel, Jonathan Pirnay, Soren Wilmsmeier
Summary: This paper introduces a new method for process-parallel Flexible Job Shop Scheduling based on quantum computing optimization, showcasing its good performance and practicality through a scientific benchmark and application to a real use-case. A managerial insight demonstrates how this approach can be integrated into existing production planning and control IT infrastructure.
CIRP JOURNAL OF MANUFACTURING SCIENCE AND TECHNOLOGY
(2021)
Review
Engineering, Manufacturing
Berend Denkena, Benjamin Bergmann, Alexander Schmidt
Summary: This study investigates the capability of sensor fusion based on principal component analysis to monitor preload loss of single nut ball screws, by studying features of different preload levels of the ball screw through selecting different ball diameters. The results show that this method can reliably detect preload levels.
CIRP JOURNAL OF MANUFACTURING SCIENCE AND TECHNOLOGY
(2021)
Article
Engineering, Industrial
Berend Denkena, Patrick Ahlborn
Summary: This paper presents a novel linear-rotary direct drive for machine tools, which combines linear and rotary movement in one drive to enhance the overall dynamics of the machine and reduce installation space.
CIRP ANNALS-MANUFACTURING TECHNOLOGY
(2022)
Article
Engineering, Industrial
Carolin Kellenbrink, Nicolas Nuebel, Andre Schnabel, Philipp Gilge, Joerg R. Seume, Berend Denkena, Stefan Helber
Summary: This paper presents a cyber-physical system demonstrator for the maintenance, repair, and overhaul (MRO) of high-pressure turbine blades of aircraft engines. By using a virtual layer and a virtual twin, the system handles the variability in damage patterns and achieves individual, flexible, and economically optimized MRO actions. It showcases the combination and innovation of research results from multiple disciplines.
INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH
(2022)
Article
Engineering, Multidisciplinary
Lars Schoenemann, Oltmann Riemer, Bernhard Karpuschewski, Per Schreiber, Heinrich Klemme, Berend Denkena
Summary: The research has found that ultra-precision cutting based on digital surface twins can accurately predict surface features and characteristics, thus supporting the development of tool offset compensation methods and improving productivity.
PRECISION ENGINEERING-JOURNAL OF THE INTERNATIONAL SOCIETIES FOR PRECISION ENGINEERING AND NANOTECHNOLOGY
(2022)
Article
Engineering, Manufacturing
B. Denkena, A. Kroedel, M. Wilckens
Summary: The use of larger CBN grains in grinding can improve material removal rates for hardened steel components and achieve higher depths of cut. Grinding with coarse grains results in lower process forces, higher residual stress, and rougher surfaces, with minimal wear observed. In some cases, using larger grains can enhance tool performance and allow for higher feed rates.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)
Article
Engineering, Electrical & Electronic
Berend Denkena, Benjamin Bergmann, Matthias Witt
Summary: To achieve increased automation and flexibility in production, it is necessary to monitor component-specific characteristics and evaluate signals highly correlated with process quality. The use of material-specific cutting force improves the sensitivity of confidence limits to process errors, allowing the force-sensitive machine to substitute the dynamometer for process monitoring.
Article
Engineering, Manufacturing
Berend Denkena, Marc-Andre Dittrich, Hai Nam Nguyen, Konrad Bild
Summary: Self-optimizing process planning uses machine learning models to correlate process parameters with surface quality, automatically adjusting optimal parameters to achieve target roughness.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)
Article
Engineering, Manufacturing
Berend Denkena, Bernd-Arno Behrens, Benjamin Bergmann, Malte Stonis, Jens Kruse, Matthias Witt
Summary: This study predicts variations in dimension and cavities during cross-wedge rolling of shafts based on measured tool pressure. Multi-linear regression models are developed to determine the resulting diameters of the shaft shoulder, showing better prediction accuracy than models based on meta-data. The sensor concept for a new cross-wedge rolling machine and the approach for monitoring machining processes of workpieces with dimensional variations are presented for upcoming studies.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)
Article
Engineering, Manufacturing
Berend Denkena, Alexander Kroedel, Steffen Heikebruegge, Kolja Meyer, Philipp Pillkahn
Summary: This study investigates the impact of machining parameters on surface topography after deep rolling, and introduces a novel tool concept to explore the predictability of surface topography for milled specimens. By adjusting parameters gradually, the minimum pressure and lateral displacement conditions were identified to ensure accuracy in predicting surface topography.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)
Article
Engineering, Manufacturing
B. Denkena, O. Pape, A. Kroedel, V. Boss, L. Ellersiek, A. Mucke
Summary: This study presents a dynamic multi-dexel based material removal simulation for additive manufacturing processes, which is able to predict high-resolution surface topography and stable parameters to improve efficiency and accuracy in repair operations.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)
Article
Engineering, Manufacturing
B. Denkena, B. Breidenstein, A. Kroedel, V. Prasanthan
Summary: The requirements for massive high-performance components are constantly increasing, and by joining different materials in one component, these contradictory requirements can be met. The final step of machining in the process chain of manufacturing hybrid components has a decisive influence on the surface and subsurface properties.
PRODUCTION ENGINEERING-RESEARCH AND DEVELOPMENT
(2021)