Article
Biochemistry & Molecular Biology
Maria Bailen, Cristina Illescas, Monica Quijada, Rafael Alberto Martinez-Diaz, Eneko Ochoa, Maria Teresa Gomez-Munoz, Juliana Navarro-Rocha, Azucena Gonzalez-Coloma
Summary: The antiparasitic activity of 23 essential oils from plants was evaluated against Leishmania and Phytomonas, finding that oils from Satureja montana, Thymus vulgaris, Mentha suaveolens, and Lavandula luisieri exhibited the best activity. Steam distillation increased the content of certain compounds in the oils. Thymol and carvacrol were identified as the major active components.
Article
Microbiology
Connie F. Canete-Gibas, James Mele, Hoja P. Patterson, Carmita J. Sanders, Dora Ferrer, Victor Garcia, Hongxin Fan, Marjorie David, Nathan P. Wiederhold
Summary: Dermatophytes are common pathogens causing skin, hair, and nail infections in humans. A study evaluated the antifungal susceptibility profiles and species identification of dermatophytes received from North America, revealing relatively common terbinafine resistance and the presence of Trichophyton indotineae in multiple areas. Continued surveillance is necessary.
JOURNAL OF CLINICAL MICROBIOLOGY
(2023)
Review
Pharmacology & Pharmacy
Laeza Alves Sampaio, Licia Tairiny Santos Pina, Mairim Russo Serafini, Debora dos Santos Tavares, Adriana Gibara Guimaraes
Summary: Carvacrol and thymol, natural compounds, exhibit antitumor and antiproliferative activities by acting through multiple signaling pathways. Carvacrol appears to be more potent than thymol in vitro, but further in vivo studies are needed to determine safe doses, toxic effects, and clarify exact mechanisms of action.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Food Science & Technology
Wu Wang, Tingting Li, Jing Chen, Yingwang Ye
Summary: This research investigates the antibacterial potential of plant essential oil components against Salmonella Enteritidis. Thymol, carvacrol, and cinnamaldehyde were found to have the best inhibitory effect on S. Enteritidis. Thymol and carvacrol not only maintained the sensory quality of chicken, but also reduced pH, moisture content, and TVB-N value.
Review
Multidisciplinary Sciences
John Lilly Jimmy
Summary: Coleus aromaticus is an herbal medicine known for its various bioactivities and medicinal properties, used in the treatment of cardiovascular disorders, respiratory disorders, and digestive diseases. It also possesses antimicrobial properties against bacterial and fungal pathogens.
Article
Food Science & Technology
Charlene Leneveu-Jenvrin, Aouatif Aboudia, Sophie Assemat, Fabienne Remize
Summary: The addition of thyme and Moroccan thyme essential oils inhibits fungal growth in pineapple juice, extending its shelf life. The low pH of the juice enhances the antifungal effect of the compounds. Despite the addition of thyme scent, the characteristic pineapple and sugary descriptors are maintained.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ruben I. Marin-Tinoco, Angie Tatiana Ortega-Ramirez, Maricela Esteban-Mendez, Oscar Silva-Marrufo, Laura E. Barragan-Ledesma, Luis M. Valenzuela-Nunez, Edwin A. Briceno-Contreras, Maria A. Sarinana-Navarrete, Abelardo Camacho-Luis, Cayetano Navarrete-Molina
Summary: In recent years, the determination of antioxidant and antibacterial activity in essential oils from wild plants has gained increasing importance. This study compared the antioxidant and antibacterial activity of Mexican oregano essential oil from different growing conditions, and found that Wild1 had the highest antioxidant activity, while Wild2 exhibited high antibacterial activity against four bacterial species.
Article
Multidisciplinary Sciences
Sandra T. Krause, Pan Liao, Christoph Crocoll, Benoit Boachon, Christiane Foerster, Franziska Leidecker, Natalie Wiese, Dongyan Zhao, Joshua C. Wood, C. Robin Buell, Jonathan Gershenzon, Natalia Dudareva, Joerg Degenhardt
Summary: Thymol and carvacrol are phenolic monoterpenes with antibacterial and anti-spasmolytic properties. Their biosynthesis involves cyclization and oxidation reactions, with specific enzymes playing key roles. The study provides new insights into the formation mechanism of these compounds.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Pharmacology & Pharmacy
Fritz Ka-Ho Ho, Albert Bolhuis, M. Begona Delgado-Charro
Summary: The study tested the use of polymeric films sprayed on the skin for the prevention and treatment of dermatophytosis, showing that the films can both prevent and treat fungal infections, and are generally acceptable for use by healthy volunteers.
Article
Immunology
Zhen Su, Weiwei Deng, Shuting Zhan, Meirong Li, Songchao Yin, Jian Chen
Summary: In this study, a mouse-human fusion TLR2 was constructed and compared to human TLR2. It was found that the fusion TLR2 activated different downstream signal pathways in response to T. rubrum and M. canis infections, leading to different inflammatory responses. This suggests that the interspecific difference of TLR2 ectodomain may contribute to the differential inflammatory manifestations between humans and mice infected by these two dermatophytes.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Food Science & Technology
Cristina Fuentes, Samuel Verdu, Ana Fuentes, Maria Jose Ruiz, Jose Manuel Barat
Summary: The study evaluated the toxicity of four widely used essential oil components on nematodes and found that these compounds had a concentration-dependent effect on nematode survival at moderate to high concentrations, with reproduction being a more sensitive endpoint for toxicity evaluation. The findings suggest that these compounds can be toxic at lower doses than those required for their biological action.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Multidisciplinary Sciences
Anita Ciesielska, Anna Kawa, Katarzyna Kanarek, Adrian Sobon, Rafal Szewczyk
Summary: This study compared the intracellular metabolite content in T. rubrum and M. canis during keratin degradation, revealing key compounds associated with interactions of these fungi with the host tissue. The metabolomic results were supported by qPCR gene expression analysis, suggesting that metabolomic analysis could aid in understanding the pathogenesis of dermatophytes.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Tareq M. Osaili, Fayeza Hasan, Dinesh Kumar Dhanasekaran, Reyad S. Obaid, Anas A. Al-Nabulsi, Mutamed Ayyash, Layal Karam, Ioannis N. Savvaidis, Richard Holley
Summary: The study evaluated the antimicrobial effect of active essential oil components on Listeria monocytogenes, Salmonella spp., and Escherichia coli O157:H7 in chicken tawook during storage. Results showed that the marinade significantly reduced L. monocytogenes and Salmonella spp. numbers at 10°C, while the addition of essential oils did not affect the pathogen populations.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Polymer Science
Muhammad Abdullah Akram, Barkat Ali Khan, Muhammad Khalid Khan, Ali Alqahtani, Sultan M. Alshahrani, Khaled M. Hosny
Summary: The study successfully developed a polymeric emulgel of eugenol and linalool for the treatment of Trichophyton rubrum infections. The emulgel showed good physical properties and demonstrated significant effects in treating the infections both in vitro and in vivo, making it a promising topical treatment option.
Article
Medicine, Research & Experimental
Isis Caroline da Silva Cirino, Caroline Ferreira de Santana, Maria Jose Ribeiro Bezerra, Igor Vasconcelos Rocha, Ana Carolina de Oliveira Luz, Henrique Douglas Melo Coutinho, Regina Celia Bressan Queiroz de Figueiredo, Antonio Raposo, Linda Heejung Lho, Heesup Han, Tereza Cristina Leal-Balbino
Summary: This study evaluated the antibacterial activity of thymol and carvacrol against multidrug-resistant Acinetobacter baumannii. The results showed that thymol and carvacrol alone effectively inhibited the bacterial growth, and their combination exhibited synergistic or additive effects. Transcriptomic analysis revealed the regulation of stress response pathways.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Agronomy
Thays Saynara Alves Menezes-Sa, Andrea Santos da Costa, Maria de Fatima Arrigoni-Blank, Arie Fitzgerald Blank, Giulia Milenna Santos Moura, Caroline Alves Soares
Summary: This study established the protocol of micropropagation and in vitro conservation for Cattleya tigrina. The semi-solid medium showed better results in terms of survival and root presence, while the liquid medium had a higher number of shoots. Pine bark provided improved height, sprouting, and rooting during acclimatization. The plants remained viable for a period of 730 days when preserved in the MS medium with 25% of the salts and at temperatures of 18 degrees C or 25 degrees C.
Article
Biotechnology & Applied Microbiology
Gustavo Henrique Teixeira Pinto, Adriana Aparecida Lopes, Lucas Junqueira de Freitas Morel, Eduardo Jose Crevelin, Carlos Eduardo Saraiva Miranda, Silvia Helena Taleb Contini, Suzelei de Castro Franca, Bianca Waleria Bertoni, Ana Maria Soares Pereira
Summary: This study evaluated the genetic diversity and chemical variability of Uncaria guianensis genotypes maintained under in vitro conditions. The results showed significant genetic diversity and chemical variability, supporting breeding studies and large-scale multiplication of plants for the production of phytomedicines.
Article
Agronomy
S. D. S. Oliveira, I. B. Gois, A. F. Blank, M. F. Arrigoni-Blank, M. Zucchi, J. B. Pinheiro, C. E. Batista, A. Alves-Pereira
Summary: This study evaluated the genetic diversity and structure of natural populations of Croton grewioides using SNP markers and selected genotypes for a species collection. The results showed high genetic variation within populations and successful separation of genotypes based on population origin. This is important for the conservation of genetic diversity in Croton grewioides.
GENETIC RESOURCES AND CROP EVOLUTION
(2022)
Article
Plant Sciences
Vilma Menezes de Jesus Prado, Raphael Amancio de Jesus, Julio Manoel Andrade Oliveira, Arie Fitzgerald Blank, Daniel Pereira Bezerra, Milena Botelho Pereira Soares, Valdenizia Rodrigues Silva, Luciano de Souza Santos, Carmen Lucia Cardoso, Adriana Ferreira Lopes Vilela, Paulo Cesar de Lima Nogueira, Valeria Regina de Souza Moraes
Summary: This study investigated the effects of seasonal variability and extraction method on the biological activities of polar extracts from Croton grewioides. The results showed that seasonal changes only affected the chemical composition of certain extracts. Different extraction methods also led to variations in the chemical profiles of the extracts. The study also identified active components with cytotoxicity against cancer cells and anti-acetylcholinesterase activity.
BRAZILIAN JOURNAL OF BOTANY
(2022)
Article
Parasitology
Dharliton Soares Gomes, Deborah Aparecida Negrao-Correa, Guilherme Silva Miranda, Joao Gustavo Mendes Rodrigues, Tamna Joanan Farias Lima Guedes, Waldecy de Lucca Junior, Jose Carlos Freitas de Sa Filho, Daniela Aparecida de Castro Nizio, Arie Fitzgerald Blank, Vera Lucia Correa Feitosa, Silvio Santana Dolabella
Summary: The study found that the essential oils from Lippia gracilis and Lippia alba showed high efficacy against adult Schistosoma mansoni worms, while the effects on schistosomula were slightly different. This research suggests that these plants could be a potential source of bioactive compounds against S. mansoni.
Article
Environmental Sciences
Natielli Conceicao Santos, Jefferson Elias da Silva, Ane Caroline Celestino Santos, Jaciele de Oliveira Dantas, Swamy Rocha Siqueira Abreu Tavares, Valfran Silva Andrade, Sara Dayan da Silva Oliveira, Arie Fitzgerald Blank, Ana Paula Albano Araujo, Leandro Bacci
Summary: Natural biological control is crucial for regulating insect pest populations in agroecosystems, but its effectiveness has been compromised due to the indiscriminate use of pesticides. Therefore, finding environmentally safe pesticides for sustainable food production is essential. This study found that essential oils from Croton grewioides and its major compounds were toxic to the soybean pest Chrysodeixis includens and the predatory bug Podisus nigrispinus.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Agricultural Engineering
Jose Carlos Freitas de Sa Filho, Daniela Aparecida de Castro Nizio, Alisson Marcel Souza de Oliveira, Mercia Freitas Alves, Roberta Camargos de Oliveira, Jose Magno Queiroz Luz, Paulo Cesar de Lima Nogueira, Maria de Fatima Arrigoni-Blank, Arie Fitzgerald Blank
Summary: The chemical composition of essential oils from Lippia alba is influenced by genetic factors and significantly affected by the environment, particularly geographic location. Variations in main compounds were observed between different locations and months, emphasizing the importance of standardization in essential oil production for stability.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Microbiology
Monise Fazolin Petrucelli, Bruna Aline M. Cantelli, Mozart Marins, Ana Lucia Fachin
Summary: Trichophyton rubrum is the leading causative agent of dermatophytosis worldwide, and keratinocytes are the first line of defense during infection. This study investigates the transcriptional response of genes during the co-culture of different developmental stages and viability of fungal conidia with HaCat cells. The results show that the developmental stage and viability of fungal conidia affect the transcriptional regulation of innate immunity genes.
Article
Agronomy
Rayssa Camargo de Oliveira, Jose Magno Queiroz Luz, Andreia Pereira dos Santos, Roberta Camargos de Oliveira, Arie Fitzgerald Blank
Summary: This study evaluated the influence of different light sources on the in vitro cultivation of Ocimum basilicum cultivars. The results showed that yellow lamps were not beneficial for basil growth, while the use of Growlux lamps promoted greater biomass growth in basil plants.
Article
Chemistry, Multidisciplinary
Pedro E. S. do Nascimento, Vilma M. J. Prado, Raphael A. de Jesus, Wenes R. da Silva, Alberto Wisniewski Jr., Jose C. F. Sa Filho, Arie F. Blank, Daniel A. de Souza, Elma R. S. A. Wartha, Paulo C. L. Nogueira, Valeria R. S. Moraes
Summary: Research on plant bioactive compounds has evolved extraction methods. This study optimized ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) to extract flavonoids from Croton grewioides Baill. The extracts were analyzed using ultra high-resolution mass spectrometry (FT-Orbitrap MS) to determine the molecular formula and propose chemical structures. Chemometric analysis showed that MAE was most effective in extracting antioxidant compounds.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Microbiology
Tamiris A. C. Santos, Kleiton P. Silva, Gabriella B. Souza, Pericles B. Alves, Rubem F. S. Menna-Barreto, Ricardo Scher, Roberta P. M. Fernandes
Summary: The antiprotozoal activity and mechanism of action of the chalcone derivative NaF on Phytomonas serpens were evaluated. The results showed that NaF treatment for 24 hours significantly reduced parasite proliferation, increased reactive oxygen species production, shortened the parasite's flagellum, and induced autophagy. Chalcone derivatives may be a potential treatment for P. serpens infection.
Article
Microbiology
Bruna Aline Cantelli, Gabriela Gonzalez Segura, Tamires Aparecida Bitencourt, Mariana Heinzen de Abreu, Monise Fazolin Petrucelli, Kamila Peronni, Pablo Rodrigo Sanches, Rene Oliveira Beleboni, Wilson Araujo da Silva Junior, Nilce Maria Martinez-Rossi, Mozart Marins, Ana Lucia Fachin
Summary: This study analyzed the transcriptome of THP-1 cells co-cultured with inactivated germinated T. rubrum conidia to characterize deep infection. Results showed increased release of IL-12 during co-culture, while the other cytokines remained unchanged. Gene expression analysis identified 83 modulated genes involved in signal transduction, cell communication, and immune response pathways. The study revealed the ability of macrophages to modulate the immune response and release proinflammatory cytokines, providing clues for exploring molecular targets in antifungal therapies involving immune system activation.
Article
Agronomy
Crislaine Alves dos Santos, Maria de Fatima Arrigoni-Blank, Itamara Bomfim Gois, Andrea Santos da Costa, Sara Dayan da Silva Oliveira, Arie Fitzgerald Blank
Summary: Yam minituber production can be improved through stem cuttings obtained from the median position of the shoot and using the commercial substrate Tropstrato Florestal (R). The number of minitubers per cutting was not significantly affected by the types of cuttings and substrates. The best results were achieved in terms of minituber length, diameter, fresh weight, and the percentage of cuttings with two minitubers.
Article
Chemistry, Medicinal
Rangel R. Bomfim, Janaine P. Oliveira, Fabiula F. Abreu, Alan S. Oliveira, Cristiane B. Correa, Edilson de Jesus, Pericles B. Alves, Marcelo B. Dos Santos, Renata Grespan, Enilton A. Camargo
Summary: This study investigated the anti-inflammatory activity of graviola seed oil and found that it can reduce ear edema and inflammation after skin injury. The main active ingredient in graviola seed oil is oleic acid.
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY
(2023)
Article
Microbiology
Nalu T. A. Peres, Elza A. S. Lang, Tamires A. Bitencourt, Vanderci M. Oliveira, Ana Lucia Fachin, Antonio Rossi, Nilce M. Martinez-Rossi
Summary: In this study, the role of the ap1 gene in Trichophyton rubrum infection was investigated. It was found that the ap1 gene plays a role in the negative control of virulence-related attributes and may contribute to the chronicity of nail infection caused by T. rubrum.
CURRENT RESEARCH IN MICROBIAL SCIENCES
(2022)
Article
Parasitology
Gabriela Martinez Moura Tavares, Hannar Angelica de Melo Alverga, Estela Moraes Felix, Giovana de Oliveira Dichman, Gabriel Monteiro Pinheiro, Yara Juliano, Priscila Paruci, Dennis Minoru Fujita, Lucas Melo Neves, Marina Tiemi Shio, Luiz Henrique da Silva Nali
Summary: This study investigated the frequency of N. gonorrhoeae infection in women in a poor area of São Paulo and found that most of the strains detected showed resistance to one or more antimicrobials.
Article
Parasitology
Qian Yao, Ying-Ying Fan, Shuang Huang, Gui-Rong Hu, Jun-Ke Song, Xin Yang, Guang-Hui Zhao
Summary: This study found that the expression of miR-4521 was upregulated during C. parvum infection, and this upregulation was related to the TLR/NF-kappa B signal pathway. Additionally, miR-4521 promoted the propagation of C. parvum in HCT-8 cells by regulating BCL2-mediated cell apoptosis through targeting foxm1.
Article
Parasitology
Cho Naing, Maxine A. Whittaker, Wong Siew Tung, Htar Aung, Joon Wah Mak
Summary: This study aimed to estimate the prevalence of zoonotic brugian filariasis in animals and compare it with the prevalence in humans in the same area. The findings suggest that cats, dogs, and leaf-eating monkeys may serve as potential reservoirs for human brugian filariasis.
Review
Parasitology
Raissa Nogueira de Brito, Susan Tanner, Julie Velasquez Runk, Juliana Hoyos
Summary: This study conducted a scoping review to identify major research themes and knowledge gaps in the social science literature on leishmaniases or Chagas disease. The findings showed that research in this field mainly focuses on the sociocultural, economic, historical, and political dimensions of the diseases. Future research should pay more attention to how social institutions and economic factors shape disease education, control measures, healthcare access, and quality of life of affected individuals.
Article
Parasitology
Minghao Zheng, Mengyao Zhang, Hao Li, Shipo Wu, Yuee Zhao, Jinlong Zhang, Yunyue Zhou, Mohamed Boie Jalloh, Kun Zhang, Lina Chen, Zhiqiang Mi, Yong Cui, Lihua Hou
Summary: Rapid and convenient detection of Plasmodium falciparum, the deadliest malaria parasite in Africa, is crucial for malaria eradication efforts in medical resource-limited settings. A CRISPR-based diagnostic method that can detect P. falciparum without nucleic acid extraction was developed and showed high sensitivity and consistency with qPCR test. It can also detect artemisinin-resistant strains and other laboratory-cultured strains. This method has great potential for clinical testing and large-scale community screening in Africa and other regions.
Article
Parasitology
Fabian Correa-Morales, Cassandra Gonzalez-Acosta, David Ibarra-Ojeda, Miguel Moreno-Garcia
Summary: Since 2002, West Nile Virus (WNV) has been reported in 18 states in Mexico. This paper discusses the proposed hypotheses for the absence of WNV outbreaks in Latin America and provides a context-specific explanation for Mexico.
Article
Parasitology
Umberto Molini, Lauren M. Coetzee, Vernon Christians, Maria Y. Hemberger, Bernard Chiwome, Maria Amukwaya, Siegfried Khaiseb, Giovanni Cattoli, William G. Dundon, Giovanni Franzo
Summary: Porcine circovirus 3 (PCV-3) has been reported globally since its first identification in 2015. Limited data on PCV-3 in Africa led to a study in Namibia, which found a high prevalence of PCV-3 in backyard piggeries, but not in commercial farms with higher biosecurity measures. The source of viral introduction and factors such as semen importation, feeding backyard pigs with human food waste, pig exchanges, and wildlife movements may be involved in the dispersal of PCV-3 within Namibia. Further studies are needed to understand the epidemiology and impact of PCV-3 on pig productivity and wildlife health.
Article
Parasitology
Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Panitnan Punyathi, Sawang Kesdangsakonwut, Tanit Kasantikul, Somporn Techangamsuwan
Summary: This study provides insights into the pathology of natural SARS-CoV-2 infection in dogs, revealing severe damage to the lungs and involvement of multiple organs. The findings suggest the potential utility of dogs as a model for studying SARS-CoV-2 infection in humans, highlighting the need for further investigation.
Article
Parasitology
Julian Avila-Jimenez, Juan David Gutierrez, Mariano Altamiranda-Saavedra
Summary: Leishmaniasis is a parasitic disease transmitted to humans by sandfly vectors and vertebrate hosts. This study used ecological niche modeling to investigate the potential distribution of host and vector species associated with cutaneous leishmaniasis transmission, revealing different distribution patterns under varying climatic conditions.
Article
Parasitology
Luis A. Gomez-Puerta, Juan Olazabal, Santiago Paredes, Juan Lopez, Miguel Anampa, Angelica Mondragon, Ana Vargas-Calla, Hugo Castillo
Summary: This study reports the first detection of Candidatus M. haemolamae infection in vicunas from the Pampa Galeras National Reserve in Peru, using molecular diagnosis. Tick-infested vicunas had a higher likelihood of being infected with Candidatus M. haemolamae compared to tick-free vicunas. Gender and age were not associated with infection.
Article
Parasitology
Berlin Londono-Renteria, Zakaria Seidu, Helena Lamptey, Michael F. Ofori, Lars Hviid, Mary Lopez-Perez
Summary: Heterozygous carriers of HbAS and HbAC have a reduced risk of severe malaria, but not immunity against Plasmodium falciparum infection. Antibody levels against gSG6-P1 peptide in Anopheles mosquito saliva can serve as a serological biomarker for exposure to Plasmodium infection. This study highlights the importance of studying the role of hemoglobinopathies in malaria transmission for improving control interventions.
Article
Parasitology
Imane Belbacha, Meryem El Azzouzi, Rajae Bensghir, Kamal Filali Marhoum, Khadija Hajjout, El Mir Elharti, Khalid Sadki, Hicham Oumzil
Summary: This study investigates the association of three SNPs in the APOBEC3G gene with disease outcomes in Moroccan HIV-1 infected patients. The rs2294367 CG genotype is strongly associated with protection against HIV-1 infection, particularly in older individuals.
Article
Parasitology
Tan Luong, Do Kien Tran, Anh Hung Pham, Thi Thu-Ha Hoang, Van Khang Pham, Quang Thai Pham, Thi Mai Hung Tran, Minh Hoa Luong, Thanh Long Pham, Jason K. Blackburn
Summary: This study examined the epidemiology of anthrax in Lai Chau province, Vietnam, using historical data. Spatial clusters of human and livestock anthrax were identified, and the characteristics of the disease were described. The study found that there were distinct differences between the high-risk areas for human and livestock anthrax, and most human cases occurred during specific seasons. Additionally, the decrease in livestock anthrax vaccine coverage was associated with an increase in disease incidence.
Article
Parasitology
Jin-tao Chen, Jian-bo Zhan, Ming-chao Zhu, Kai-ji Li, Man-qing Liu, Bin Hu, Kun Cai, Hai-rong Xiong, Shu-liang Chen, Wei-long Tan, Liang-jun Chen, Wei Hou
Summary: This study investigated the prevalence and variation of orthohantavirus in rodents and humans in Hubei province, China. It identified the diversity of orthohantaviruses circulating in the region, with the HV004-like subtype being the main genotype in rodents and patients. This highlights the importance of continued attention and research on orthohantaviruses, especially newly identified strains.
