Article
Parasitology
Pilate N. Kwi, Elvis E. Ewane, Marcel N. Moyeh, Livinus N. Tangi, Vincent N. Ntui, Francis Zeukeng, Denis D. Sofeu-Feugaing, Eric A. Achidi, Fidelis Cho-Ngwa, Alfred Amambua-Ngwa, Jude D. Bigoga, Tobias O. Apinjoh
Summary: The vectorial diversity, dynamics, and infectivity of mosquitoes in the slopes of Mount Cameroon vary across different seasons and altitudes, which has implications for malaria transmission and control.
PARASITES & VECTORS
(2022)
Review
Infectious Diseases
P. Doumbe-Belisse, E. Kopya, C. S. Ngadjeu, N. Sonhafouo-Chiana, A. Talipouo, L. Djamouko-Djonkam, H. P. Awono-Ambene, C. S. Wondji, F. Njiokou, C. Antonio-Nkondjio
Summary: Sub-Saharan Africa is experiencing rapid urban population growth, with over 75% of the population expected to be living in urban settings by 2050. The study found high malaria transmission in rural compared to urban areas, but most cities have seen an increase in transmission after 2003. Anopheles gambiae complex species were the predominant vectors in urban settings, with larvae adapting to various aquatic habitats.
Article
Parasitology
Emilie S. Ngongang-Yipmo, Magellan Tchouakui, Benjamin D. Menze, Leon M. J. Mugenzi, Flobert Njiokou, Charles S. Wondji
Summary: This study investigated the efficacy of different brands of LLINs against pyrethroid-resistant mosquitoes and their post-exposure effect. The results showed that standard bednets had reduced efficacy against resistant mosquitoes in the field, but still induced delayed mortality in exposed populations. The study also highlighted the importance of using new-generation nets that do not solely rely on pyrethroids.
PARASITES & VECTORS
(2022)
Article
Biochemistry & Molecular Biology
Nelly Armanda Kala-Chouakeu, Paulette Ndjeunia-Mbiakop, Idriss Nasser Ngangue-Siewe, Konstantinos Mavridis, Vasileia Balabanidou, Roland Bamou, Mabu Maxim Bindamu, Abdou Talipouo, Landre Djamouko-Djonkam, Jean Arthur Mbida-Mbida, Jeanette Tombi, John Vontas, Timoleon Tchuinkam, Christophe Antonio-Nkondjio
Summary: This study assessed the pyrethroid resistance profile of Anopheles gambiae populations in different ecological settings in Cameroon. The results showed a high level of pyrethroid resistance across the country, with varying resistance patterns. This calls for further actions to mitigate the impact of insecticide resistance on vector control measures.
Article
Genetics & Heredity
Yvan Fotso-Toguem, Billy Tene-Fossog, Leon M. J. Mugenzi, Murielle J. Wondji, Flobert Njiokou, Hilary Ranson, Charles S. Wondji
Summary: The polymorphisms of CYP6M2 and CYP6P4 were analyzed to detect potential resistance markers in Anopheles coluzzii and Anopheles gambiae. The study found significant overexpression of CYP6M2 and CYP6P4 in resistant mosquitos, and a lower diversity in the upstream region of CYP6P4 potentially associated with resistance.
Article
Physics, Particles & Fields
Onkar Parrikar, Vivek Singh
Summary: The study focuses on the canonical purification of pure bi-partite states obtained through sources in the Euclidean path integral, and its Lorentzian bulk dual in holographic conformal field theories. It is found that the mismatch in classical expansions at the quantum extremal surface due to quantum corrections can be supported by a shock in the bulk matter stress tensor in order to satisfy Einstein's equations.
JOURNAL OF HIGH ENERGY PHYSICS
(2023)
Article
Mathematics, Interdisciplinary Applications
Naomichi Makino
Summary: This study discusses a Correspondence Analysis (CA) formulation based on Canonical Correlation Analysis (CCA) and proposes an alternative CCA-based formulation that allows oblique rotation. The benefits of the proposed formulation are demonstrated through simulation studies and real data examples.
Article
Biochemistry & Molecular Biology
Michael Piameu, Philippe Nwane, Wilson Toussile, Konstantinos Mavridis, Nadja Christina Wipf, Paraudie France Kouadio, Lili Ranaise Mbakop, Stanislas Mandeng, Wolfgang Eyisap Ekoko, Jean Claude Toto, Kelly Lionelle Ngaffo, Petronile Klorane Ngo Etounde, Arthur Titcho Ngantchou, Mouhamadou Chouaibou, Pie Muller, Parfait Awono-Ambene, John Vontas, Josiane Etang
Summary: A study conducted in a city in Cameroon revealed widespread insecticide resistance in malaria vector populations, with fluctuating resistance intensity, detection of multiple resistance-associated molecular markers, and highly upregulated gene expression levels, posing potential challenges for future malaria control interventions.
Article
Entomology
Salomon Efa, Emmanuel Elanga-Ndille, Yacouba Poumachu, Billy Tene, Jacqueline Ze Mikande, Njoumemi Zakariaou, Charles S. Wondji, Cyrille Ndo
Summary: Monitoring insecticide resistance in major malaria vectors like Anopheles gambiae s.l. is crucial for designing effective vector control strategies and preventing the spread of resistance. This study in Ebolowa, Southern Cameroon, revealed high resistance to pyrethroid insecticides in Anopheles coluzzii, posing a risk to the efficacy of Long-Lasting Insecticidal Nets (LLINs) used for malaria control. Urgent implementation of resistance management strategies is needed to maintain the effectiveness of insecticide-based interventions.
Article
Genetics & Heredity
Nelly Armanda Kala-Chouakeu, Edmond Kopya, Vasileia Balabanidou, Borel Tchamen Djiappi, Kyriaki Maria Papapostolou, Timoleon Tchuinkam, Christophe Antonio-Nkondjio
Summary: This study assessed the resistance profile of Anopheles pharoensis to DDT in the far-north region of Cameroon and found high DDT resistance in some populations without kdr mutations. It also identified a high production of cuticular hydrocarbon in these populations. These findings describe the development of cuticle resistance in An. pharoensis for the first time.
Article
Physics, Particles & Fields
Chris Akers, Thomas Faulkner, Simon Lin, Pratik Rath
Summary: In this paper, we analyze a network of two random tensors to study the reflected entanglement spectrum and its connection to multiboundary wormholes. The spectrum is controlled by the representation theory of the Temp erley-Lieb algebra and can be expressed as a sum over different irreducible representations labeled by a topological index. We provide a gravitational interpretation and confirm the holographic duality of the reflected entropy away from phase transitions. Moreover, we discover non-perturbative contributions from new geometries near phase transitions and speculate the emergence of a non-trivial von Neumann algebra associated with the Temp erley-Lieb algebra in a modular flowed version of reflected entropy.
JOURNAL OF HIGH ENERGY PHYSICS
(2023)
Article
Physics, Particles & Fields
Onkar Parrikar, Vivek Singh
Summary: We study the canonical purification of bi-partite states and find that the Lorentzian bulk dual consists of the entanglement wedge and the CRT image, but with a mismatch due to quantum corrections that requires a shock in the bulk matter stress tensor. By perturbatively working with double-trace sources, we demonstrate that the bulk matter state in the dual exactly has this quantum extremal shock in the stress tensor, indicating the emergence of gravitational physics from the CFT entanglement structure in the presence of quantum corrections.
JOURNAL OF HIGH ENERGY PHYSICS
(2023)
Article
Green & Sustainable Science & Technology
Zaira-Jazmin Zarate-Santana, Maria-Carmen Patino-Alonso, Ana-Belen Sanchez-Garcia, Purificacion Galindo-Villardon
Summary: Learning approaches play a crucial role in sustainability education, with deep learning methods being effective in coping with academic stress. Male and female students exhibit different coping strategies when faced with stress, emphasizing the importance of variables such as deep learning and gender in the teaching and learning sustainability process.
Article
Infectious Diseases
Magellan Tchouakui, Riccado F. Thiomela, Elysee Nchoutpouen, Benjamin D. Menze, Cyrille Ndo, Dorothy Achu, Raymond N. Tabue, Flobert Njiokou, Ateba Joel, Charles S. Wondji
Summary: The study found that compared to pyrethroid-only nets, the PBO-pyrethroid-chlorfenapyr and dual active ingredients nets were more effective against pyrethroid-resistant malaria vectors. Therefore, these new nets can be used for malaria control in Cameroon, but their effectiveness needs to be validated in other locations and on other major malaria vectors.
INFECTIOUS DISEASES OF POVERTY
(2023)
Article
Parasitology
Claudine Grace Tatsinkou Maffo, Maurice Marcel Sandeu, Amen Nakebang Fadel, Magellan Tchouakui, Daniel Nguiffo Nguete, Benjamin Menze, Michael O. Kusimo, Flobert Njiokou, Grant L. Hughes, Charles S. Wondji
Summary: This study investigated the prevalence and maternal transmission of Asaia in natural populations of Anopheles mosquitoes in Cameroon. Results showed that Asaia was vertically transmitted at a high frequency among four mosquito species, providing valuable information for using Asaia in the control of malaria in sub-Saharan Africa.
PARASITES & VECTORS
(2021)
Article
Parasitology
Raquel Montanez-Gonzalez, Alexandra C. Vallera, Maria Calzetta, Verena Pichler, Rachel R. Love, Moussa W. Guelbeogo, Roch K. Dabire, Marco Pombi, Carlo Costantini, Frederic Simard, Alessandra della Torre, Nora J. Besansky
Summary: In this study, tandem PCR-RFLP assays were developed for accurate genotyping of inversion 2Rc in An. coluzzii. Using these assays, it was found that employing two PCR-RFLP assays in tandem could improve genotyping reliability, ensuring over 99% accuracy in genotypic assignments. This approach is simple, cost-effective, and widely accessible, providing a crucial tool for investigating eco-phenotypes relevant to malaria epidemiology and vector control.
PARASITES & VECTORS
(2021)
Article
Evolutionary Biology
Antoine M. Dujon, Joel S. Brown, Delphine Destoumieux-Garzon, Marion Vittecoq, Rodrigo Hamede, Aurelie Tasiemski, Justine Boutry, Sophie Tissot, Catherine Alix-Panabieres, Pascal Pujol, Francois Renaud, Frederic Simard, Benjamin Roche, Beata Ujvari, Frederic Thomas
Summary: Recent pandemics have underscored the need to interconnect animal, human, and environmental health disciplines, under the concept of One Health. While the One Health approach primarily focuses on zoonotic diseases, the argument is made for cancers to also be a key concern due to human activities impacting the natural world and potentially leading to cancer emergence. Understanding transmissible cancers in animals, including humans, is crucial to prevent biodiversity loss and potential pandemics, while also offering new insights into cancer prevention and treatment strategies through research on tumor suppressor mechanisms.
EVOLUTIONARY APPLICATIONS
(2021)
Article
Parasitology
Amadou S. Traore, Angelique Porciani, Nicolas Moiroux, Roch K. Dabire, Frederic Simard, Carlo Costantini, Karine Mouline
Summary: This study investigated the behavioural activity changes of Anopheles coluzzii mosquitoes in different physiological states, revealing that insemination and blood digestion status can influence the rhythmic features of locomotor activity. In dim light conditions, inseminated females may exhibit sustained activity during the daytime, potentially impacting residual transmission of malarial parasites.
PARASITES & VECTORS
(2021)
Article
Multidisciplinary Sciences
Neil M. Longo-Pendy, Billy Tene-Fossog, Robert E. Tawedi, Ousman Akone-Ella, Celine Toty, Nil Rahola, Jean-Jacques Braun, Nicolas Berthet, Pierre Kengne, Carlo Costantini, Diego Ayala
Summary: The study found that Anopheles coluzzii exhibits ecological plasticity to breed in diverse aquatic conditions, with a predominance in breeding sites rich in ions. Additionally, gene expression patterns were comparable between urban and rural habitats, indicating a broad response to ions concentrations of various origins. This suggests that Anopheles coluzzii has a plastic response to occupy both coastal and urban habitats, which has important implications for malaria control efforts amidst rapid urban expansion in Africa in the near future.
SCIENTIFIC REPORTS
(2021)
Article
Parasitology
Sebastien Boyer, Pierre-Olivier Maquart, Kalyan Chhuoy, Kimhuor Suor, Moeun Chhum, Kimly Heng, Sokkeang Leng, Didier Fontenille, Sebastien Marcombe
Summary: This study suggests that Bacillus thuringiensis ser. israelensis (Bti) can be considered as a serious alternative to the larvicide temephos for controlling Aedes aegypti larvae, and the carbamate adulticides propoxur and bendiocarb should be used instead of widely used pyrethroid insecticides for controlling adult Aedes aegypti on land under mosaic farming and crop rotation in Cambodia, as the insects have shown resistance to the latter type of insecticide. Research on insecticide resistance and innovative and effective vector control strategies should be prioritized in public health in Cambodia.
PARASITES & VECTORS
(2022)
Article
Entomology
Moussa Namountougou, Dieudonne Diloma Soma, Ibrahim Sangare, Rousseau Djouaka, Aristide S. Hien, Mahamadi Kientega, Alexandre P. Didier Kabore, Simon P. Sawadogo, Azize Millogo, Mahamoudou Balbone, Thierry Baldet, Jean-Bosco Ouedraogo, Thibaud Martin, Frederic Simard, Georges Anicet Ouedraogo, Abdoulaye Diabate, Olivier Gnankine, Roch Kounbobr Dabire
Summary: Resistance to insecticides in the mosquito Anopheles gambiae s.l can jeopardize malaria vector control strategies. Our study assessed the impact of three cotton pest management strategies on the susceptibility to insecticides and the frequency of kdr L1014F mutations in the mosquito population. The results showed reduced susceptibility to insecticides and no relationship between cotton pest control strategies and kdr L1014F frequency.
INTERNATIONAL JOURNAL OF PEST MANAGEMENT
(2022)
Article
Multidisciplinary Sciences
Claire Sangbakembi-Ngounou, Carlo Costantini, Neil Michel Longo-Pendy, Carine Ngoagouni, Ousman Akone-Ella, Nil Rahola, Sylvie Cornelie, Pierre Kengne, Emmanuel Rivalyn Nakoune, Narcisse Patrice Komas, Diego Ayala
Summary: A study in Bangui, Central African Republic, found that there is a daily rhythmicity in the biting behavior of Anopheles mosquitoes, with a significant amount of indoor biting occurring during daytime. This rhythmicity could potentially limit the effectiveness of malaria control interventions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Idriss Nasser Ngangue-Siewe, Paulette Ndjeunia-Mbiakop, Nelly Armanda Kala-Chouakeu, Roland Bamou, Abdou Talipouo, Landre Djamouko-Djonkam, John Vontas, Konstantinos Mavridis, Jeannette Tombi, Timoleon Tchuinkam, Jean Arthur Mbida-Mbida, Christophe Antonio-Nkondjio
Summary: The spread of resistance to pyrethroids in malaria vectors is a major concern for control measures. This study assessed the resistance profile of Anopheles gambiae mosquitoes in Cameroon and found high frequencies of resistance to bendiocarb and malathion. Genes associated with metabolic resistance and cuticle resistance were found to be overexpressed. The rapid spread of resistance to these insecticides could compromise future control strategies.
Article
Biochemistry & Molecular Biology
Nelly Armanda Kala-Chouakeu, Paulette Ndjeunia-Mbiakop, Idriss Nasser Ngangue-Siewe, Konstantinos Mavridis, Vasileia Balabanidou, Roland Bamou, Mabu Maxim Bindamu, Abdou Talipouo, Landre Djamouko-Djonkam, Jean Arthur Mbida-Mbida, Jeanette Tombi, John Vontas, Timoleon Tchuinkam, Christophe Antonio-Nkondjio
Summary: This study assessed the pyrethroid resistance profile of Anopheles gambiae populations in different ecological settings in Cameroon. The results showed a high level of pyrethroid resistance across the country, with varying resistance patterns. This calls for further actions to mitigate the impact of insecticide resistance on vector control measures.
Article
Virology
Stella Mariette Nana-Ndjangwo, Borel Djiappi-Tchamen, Ruth Mony, Maurice Demanou, Joyce Keumezeu-Tsafack, Roland Bamou, Parfait Awono-Ambene, Charles Felix Bilong Bilong, Christophe Antonio-Nkondjio
Summary: This study assessed the prevalence of dengue and chikungunya in urban and rural settings in Cameroon using three diagnostic tools. The results showed a high prevalence of these diseases in Yaounde and Dizangue, with variations depending on the diagnostic tool used.
Article
Public, Environmental & Occupational Health
Emilie Pondeville, Anna-Bella Failloux, Frederic Simard, Petr Volf, Andrea Crisanti, Roya Elaine Haghighat-Khah, Nuria Busquets, Francesc Xavier Abad, Anthony J. Wilson, Romeo Bellini, Sarah Marsh Arnaud, Alain Kohl, Eva Veronesi
Summary: This article provides expert advice on safely handling mosquitoes and the pathogens they transmit, based on the experience of the Infravec2 consortium. It can also be used as a basis for research with other arthropods.
PATHOGENS AND GLOBAL HEALTH
(2023)
Article
Microbiology
Irina Bemba, Arsene Lenga, Herman Parfait Awono-Ambene, Christophe Antonio-Nkondjio
Summary: This study provides updated information on the distribution of tsetse fly populations and the circulation of trypanosome species in different active HAT foci in Congo. The results suggest a high risk of potential transmission of animal trypanosomes in these foci.
Review
Biodiversity Conservation
David Renault, Stephane A. P. Derocles, Phillip Haubrock, Frederic Simard, Ross N. Cuthbert, Claire Valiente-Moro
Summary: Invasive hematophagous arthropods, such as mosquitoes, pose a threat to the health of the planet by carrying and spreading various pathogens and parasites that cause diseases. Understanding the biology and ecology of these invasive species is crucial for efforts to reduce human and animal morbidity and mortality. This review article summarizes the research on invasive hematophagous arthropods globally, emphasizing mosquitoes, and provides management recommendations.
BIOLOGICAL INVASIONS
(2023)
Article
Microbiology
Irina Bemba, Arsene Lenga, Herman Parfait Awono-Ambene, Christophe Antonio-Nkondjio
Summary: Although the incidence of Human African Trypanosomiasis (HAT) has significantly decreased in the Republic of Congo, the disease still persists in some active areas. A study was conducted to assess the knowledge and practices of the population regarding HAT and the prevalence of trypanosomes in animals in three HAT foci. The study found a high rate of trypanosome infection in domestic animals and the use of personal measures to prevent tsetse fly bites. Regular monitoring and control of tsetse fly populations, along with updating information on the HAT animal reservoir and population knowledge, are crucial for the elimination of gHAT in the Republic of Congo.
MICROBIOLOGY RESEARCH
(2023)
Article
Parasitology
Gabriela Martinez Moura Tavares, Hannar Angelica de Melo Alverga, Estela Moraes Felix, Giovana de Oliveira Dichman, Gabriel Monteiro Pinheiro, Yara Juliano, Priscila Paruci, Dennis Minoru Fujita, Lucas Melo Neves, Marina Tiemi Shio, Luiz Henrique da Silva Nali
Summary: This study investigated the frequency of N. gonorrhoeae infection in women in a poor area of São Paulo and found that most of the strains detected showed resistance to one or more antimicrobials.
Article
Parasitology
Qian Yao, Ying-Ying Fan, Shuang Huang, Gui-Rong Hu, Jun-Ke Song, Xin Yang, Guang-Hui Zhao
Summary: This study found that the expression of miR-4521 was upregulated during C. parvum infection, and this upregulation was related to the TLR/NF-kappa B signal pathway. Additionally, miR-4521 promoted the propagation of C. parvum in HCT-8 cells by regulating BCL2-mediated cell apoptosis through targeting foxm1.
Article
Parasitology
Cho Naing, Maxine A. Whittaker, Wong Siew Tung, Htar Aung, Joon Wah Mak
Summary: This study aimed to estimate the prevalence of zoonotic brugian filariasis in animals and compare it with the prevalence in humans in the same area. The findings suggest that cats, dogs, and leaf-eating monkeys may serve as potential reservoirs for human brugian filariasis.
Review
Parasitology
Raissa Nogueira de Brito, Susan Tanner, Julie Velasquez Runk, Juliana Hoyos
Summary: This study conducted a scoping review to identify major research themes and knowledge gaps in the social science literature on leishmaniases or Chagas disease. The findings showed that research in this field mainly focuses on the sociocultural, economic, historical, and political dimensions of the diseases. Future research should pay more attention to how social institutions and economic factors shape disease education, control measures, healthcare access, and quality of life of affected individuals.
Article
Parasitology
Minghao Zheng, Mengyao Zhang, Hao Li, Shipo Wu, Yuee Zhao, Jinlong Zhang, Yunyue Zhou, Mohamed Boie Jalloh, Kun Zhang, Lina Chen, Zhiqiang Mi, Yong Cui, Lihua Hou
Summary: Rapid and convenient detection of Plasmodium falciparum, the deadliest malaria parasite in Africa, is crucial for malaria eradication efforts in medical resource-limited settings. A CRISPR-based diagnostic method that can detect P. falciparum without nucleic acid extraction was developed and showed high sensitivity and consistency with qPCR test. It can also detect artemisinin-resistant strains and other laboratory-cultured strains. This method has great potential for clinical testing and large-scale community screening in Africa and other regions.
Article
Parasitology
Fabian Correa-Morales, Cassandra Gonzalez-Acosta, David Ibarra-Ojeda, Miguel Moreno-Garcia
Summary: Since 2002, West Nile Virus (WNV) has been reported in 18 states in Mexico. This paper discusses the proposed hypotheses for the absence of WNV outbreaks in Latin America and provides a context-specific explanation for Mexico.
Article
Parasitology
Umberto Molini, Lauren M. Coetzee, Vernon Christians, Maria Y. Hemberger, Bernard Chiwome, Maria Amukwaya, Siegfried Khaiseb, Giovanni Cattoli, William G. Dundon, Giovanni Franzo
Summary: Porcine circovirus 3 (PCV-3) has been reported globally since its first identification in 2015. Limited data on PCV-3 in Africa led to a study in Namibia, which found a high prevalence of PCV-3 in backyard piggeries, but not in commercial farms with higher biosecurity measures. The source of viral introduction and factors such as semen importation, feeding backyard pigs with human food waste, pig exchanges, and wildlife movements may be involved in the dispersal of PCV-3 within Namibia. Further studies are needed to understand the epidemiology and impact of PCV-3 on pig productivity and wildlife health.
Article
Parasitology
Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Panitnan Punyathi, Sawang Kesdangsakonwut, Tanit Kasantikul, Somporn Techangamsuwan
Summary: This study provides insights into the pathology of natural SARS-CoV-2 infection in dogs, revealing severe damage to the lungs and involvement of multiple organs. The findings suggest the potential utility of dogs as a model for studying SARS-CoV-2 infection in humans, highlighting the need for further investigation.
Article
Parasitology
Julian Avila-Jimenez, Juan David Gutierrez, Mariano Altamiranda-Saavedra
Summary: Leishmaniasis is a parasitic disease transmitted to humans by sandfly vectors and vertebrate hosts. This study used ecological niche modeling to investigate the potential distribution of host and vector species associated with cutaneous leishmaniasis transmission, revealing different distribution patterns under varying climatic conditions.
Article
Parasitology
Luis A. Gomez-Puerta, Juan Olazabal, Santiago Paredes, Juan Lopez, Miguel Anampa, Angelica Mondragon, Ana Vargas-Calla, Hugo Castillo
Summary: This study reports the first detection of Candidatus M. haemolamae infection in vicunas from the Pampa Galeras National Reserve in Peru, using molecular diagnosis. Tick-infested vicunas had a higher likelihood of being infected with Candidatus M. haemolamae compared to tick-free vicunas. Gender and age were not associated with infection.
Article
Parasitology
Berlin Londono-Renteria, Zakaria Seidu, Helena Lamptey, Michael F. Ofori, Lars Hviid, Mary Lopez-Perez
Summary: Heterozygous carriers of HbAS and HbAC have a reduced risk of severe malaria, but not immunity against Plasmodium falciparum infection. Antibody levels against gSG6-P1 peptide in Anopheles mosquito saliva can serve as a serological biomarker for exposure to Plasmodium infection. This study highlights the importance of studying the role of hemoglobinopathies in malaria transmission for improving control interventions.
Article
Parasitology
Imane Belbacha, Meryem El Azzouzi, Rajae Bensghir, Kamal Filali Marhoum, Khadija Hajjout, El Mir Elharti, Khalid Sadki, Hicham Oumzil
Summary: This study investigates the association of three SNPs in the APOBEC3G gene with disease outcomes in Moroccan HIV-1 infected patients. The rs2294367 CG genotype is strongly associated with protection against HIV-1 infection, particularly in older individuals.
Article
Parasitology
Tan Luong, Do Kien Tran, Anh Hung Pham, Thi Thu-Ha Hoang, Van Khang Pham, Quang Thai Pham, Thi Mai Hung Tran, Minh Hoa Luong, Thanh Long Pham, Jason K. Blackburn
Summary: This study examined the epidemiology of anthrax in Lai Chau province, Vietnam, using historical data. Spatial clusters of human and livestock anthrax were identified, and the characteristics of the disease were described. The study found that there were distinct differences between the high-risk areas for human and livestock anthrax, and most human cases occurred during specific seasons. Additionally, the decrease in livestock anthrax vaccine coverage was associated with an increase in disease incidence.
Article
Parasitology
Jin-tao Chen, Jian-bo Zhan, Ming-chao Zhu, Kai-ji Li, Man-qing Liu, Bin Hu, Kun Cai, Hai-rong Xiong, Shu-liang Chen, Wei-long Tan, Liang-jun Chen, Wei Hou
Summary: This study investigated the prevalence and variation of orthohantavirus in rodents and humans in Hubei province, China. It identified the diversity of orthohantaviruses circulating in the region, with the HV004-like subtype being the main genotype in rodents and patients. This highlights the importance of continued attention and research on orthohantaviruses, especially newly identified strains.