Article
Health Care Sciences & Services
Hyemi Hwang, Yeonjae Han, Geun-Young Park, Soohwan Lee, Hae-Yeon Park, Sun Im
Summary: This study investigated the effects of tDCS on swallowing function in individuals with different COMT gene polymorphisms. The results showed that individuals with COMT Val/Val polymorphism experienced improvement in swallowing motor function after tDCS, while those with COMT Met carrier group did not show significant changes.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Multidisciplinary Sciences
Saba Kanwal, Syeda Farhana Kazmi
Summary: Spousal violence in Pakistan is a neglected public health problem that lacks research. This study analyzes the correlation between impulsivity, impulsive aggression, and borderline personality features among violent spouses, and explores the moderating role of impulsive aggression. The results provide valuable insights for physicians and practitioners dealing with individuals who have experienced violence.
Article
Neurosciences
L. Bonetti, S. E. P. Bruzzone, N. A. Sedghi, N. T. Haumann, T. Paunio, K. Kantojarvi, M. Kliuchko, P. Vuust, E. Brattico
Summary: This study explores the influence of different COMT gene variants on auditory prediction processes, demonstrating that catecholamine levels determined by genetics can affect the brain's mechanisms for detecting deviant events.
Article
Neurosciences
Mi Su, Yongyan Song
Summary: This meta-analysis did not find a significant association between COMT Val158Met polymorphism and PTSD. The Hardy-Weinberg equilibrium status of genotype distributions may influence the relationship between the two factors. Further large-scale population-based studies are needed to evaluate the impact of COMT Val158Met polymorphism on the risk of PTSD.
NEUROPSYCHOBIOLOGY
(2022)
Review
Clinical Neurology
Jun Chu, Kaili Zheng, Jinyao Yi
Summary: Aggressive behaviors are prevalent in patients with Borderline Personality Disorder, with neuroimaging studies linking this aggression to alterations in various brain regions, especially in frontal-limbic areas. Studies have highlighted abnormalities in prefrontal cortices and limbic structures, with less focus on parietal and temporal regions. Connectivity studies have shown the importance of frontal-limbic interactions in regulating aggression, while conflicting findings may be due to disparities in controlling variables like gender, anatomical subdivisions, and comorbidities.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2022)
Article
Behavioral Sciences
Gerly Tamm, Kairi Kreegipuu, Jaanus Harro
Summary: This study aimed to describe the interaction between platelet MAO activity and COMT Val158Met genotype in visual working memory updating. The results suggest that the effect of COMT Val158Met on updating efficiency depends on the level of platelet MAO activity.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Medicine, General & Internal
Zhonggui Xiong, Jiong Yan, Shuhua Shi
Summary: This study found that Val158Met polymorphisms of the COMT gene and serum concentrations of catecholaminergic neurotransmitters are associated with ADHD children and adolescents, with significant differences between the two groups.
Article
Behavioral Sciences
Bernetta Zi Wei Kwek, Min Tan, Long Yu, Wei Zhou, Chia-chen Chang, Daiqin Li
Summary: Consistent interindividual differences in aggression were observed in both male and female jade jumping spiders, with aggressive spiders being more predictable. Females showed a preference for aggressive males, and predictable aggressive males were more likely to win contests.
Article
Psychiatry
Mohamed Nasreldin Sadek, Esraa Shehata Ismail, Ayman Isamil Kamel, Alia Adel Saleh, Ayda Aly Youssef, Nagwan Mohamed Madbouly
Summary: The study revealed significant structural alterations in the corpus callosum of adolescent females with Borderline Personality Disorder, which are associated with symptoms of emotional dysregulation and impulsivity.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Integrative & Complementary Medicine
Takuya Watanabe, Hikari Iba, Hiroshi Moriyama, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki
Summary: SST is believed to attenuate stress-induced aggressive behavior by modulating dopaminergic signaling.
JOURNAL OF TRADITIONAL AND COMPLEMENTARY MEDICINE
(2022)
Article
Psychology, Multidisciplinary
Meiping Wang, Pian Chen, Hang Li, Andrew Haddon Kemp, Wenxin Zhang
Summary: This study used 70 Chinese male undergraduate students as participants and found that COMT Val158Met gene polymorphism has an impact on hostility and aggressive motivation under different social conditions. Met allele carriers showed more pronounced differences in feelings of hostility and aggressive motivation under conditions of exclusion compared to Val/Val homozygotes.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychiatry
Matthew T. Tull, Margaret M. Baer, Tara L. Spitzen, Aaron A. Lee, Eric J. Vallender, Michael R. Garrett, Michael D. Anestis, Kim L. Gratz
Summary: The study examined the relationship between borderline personality disorder (BPD) symptoms and the catechol-o-methyltransferase (COMT) Val158Met polymorphism with suicidal ideation and suicide attempts. Results indicated that Val/Val carriers have a higher probability of lifetime suicide attempts as BPD symptom severity increases, suggesting an increased risk for suicide attempts.
PSYCHIATRY RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Olga A. Korczeniewska, Fengshen Kuo, Ching-Yu Huang, Cibele Nasri-Heir, Junad Khan, Rafael Benoliel, Craig Hirschberg, Eli Eliav, Scott R. Diehl
Summary: This study investigated the impact of the COMT gene on pain sensitivity and found that the low pain sensitivity haplotype is influenced by genetic variation in gene expression, rather than SNP rs4680. The results suggest that the frequency of the COMT low pain sensitivity haplotype varies widely among global populations.
JOURNAL OF GENE MEDICINE
(2021)
Article
Criminology & Penology
Lorna Stead, Gayle Brewer, Kathryn Gardner, Roxanne Khan
Summary: The study found that personality disorder traits, love styles, and rejection sensitivity collectively influenced perpetration and victimisation of sexual coercion in women. Borderline traits played a significant role in coercion involving emotional manipulation and deception, while Ludus and rejection sensitivity were also associated with victimisation.
JOURNAL OF SEXUAL AGGRESSION
(2022)
Article
Psychology, Clinical
Bethany G. Edwards, J. Michael Maurer, Carla L. Harenski, Kent A. Kiehl
Summary: This study found differential relationships between psychopathic and BPD traits and alcohol and drug use. Specifically, BPD traits were more related to alcohol use, while lifestyle-antisocial psychopathic traits were more related to drug use.
CRIMINAL JUSTICE AND BEHAVIOR
(2021)