A mechanistic look at the effects of adversity early in life on cardiovascular disease risk during adulthood

Clinical depression, antidepressant use and risk of future cardiovascular disease

(2013) Iffat Rahman et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Early Weaning Stress in Pigs Impairs Innate Mucosal Immune Responses to Enterotoxigenic E. coli Challenge and Exacerbates Intestinal Injury and Clinical Disease

(2013) Brittney L. McLamb et al.   PLoS One

Early Life Stress Interacts with the Diet Deficiency of Omega-3 Fatty Acids during the Life Course Increasing the Metabolic Vulnerability in Adult Rats

(2013) Juliana R. Bernardi et al.   PLoS One

Development of asthmatic inflammation in mice following early-life exposure to ambient environmental particulates and chronic allergen challenge

(2012) C. Herbert et al.   Disease Models & Mechanisms

Postnatal maternal separation modifies the response to an obesogenic diet in adulthood in rats

(2012) L. Paternain et al.   Disease Models & Mechanisms

Maternal behavior and offspring resiliency to maternal separation in c57bl/6 mice

(2012) Lawrence S. Own et al.   HORMONES AND BEHAVIOR

Early life stress and blood pressure levels in late adulthood

(2012) H Alastalo et al.   JOURNAL OF HUMAN HYPERTENSION

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus

(2012) M. Suderman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiovascular Morbidity and Mortality in Finnish Men and Women Separated Temporarily From Their Parents in Childhood—A Life Course Study

(2012) Hanna Alastalo et al.   PSYCHOSOMATIC MEDICINE

Early maternal separation has mild effects on cardiac autonomic balance and heart structure in adult male rats

(2012) M. Trombini et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Strain-specific cognitive deficits in adult mice exposed to early life stress.

(2011) Mukti Mehta et al.   BEHAVIORAL NEUROSCIENCE

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

Early Life Stress Enhances Angiotensin II–Mediated Vasoconstriction by Reduced Endothelial Nitric Oxide Buffering Capacity

(2011) Analia S. Loria et al.   HYPERTENSION

The arcuate NPY, POMC, and CART expressions responding to food deprivation are exaggerated in young female rats that experienced neonatal maternal separation

(2011) S.B. Yoo et al.   NEUROPEPTIDES

Parental Death during Childhood and Adult Cardiovascular Risk in a Developing Country: The Guangzhou Biobank Cohort Study

(2011) C. Mary Schooling et al.   PLoS One

Maternal separation produces lasting changes in cortisol and behavior in rhesus monkeys

(2011) X. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deprivation of maternal care has long-lasting consequences for the hypothalamic-pituitary-adrenal axis of zebra finches

(2011) S. B. Banerjee et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Dietary n-3 polyunsaturated fatty acid deprivation together with early maternal separation increases anxiety and vulnerability to stress in adult rats

(2011) Géraldine Mathieu et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Gene–environment interactions: early life stress and risk for depressive and anxiety disorders

(2011) Nicole R. Nugent et al.   PSYCHOPHARMACOLOGY

The Relationship between Childhood Parental Loss and Metabolic Syndrome in Obese Subjects

(2011) Alessandra Alciati et al.   STRESS AND HEALTH

Resistance to Early-Life Stress in Mice: Effects of Genetic Background and Stress Duration

(2011) Hélène M. Savignac et al.   Frontiers in Behavioral Neuroscience

Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats

(2010) Analia S. Loria et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Neonatal Maternal Separation Alters Immune, Endocrine, and Behavioral Responses to Acute Theiler’s Virus Infection in Adult Mice

(2010) M. W. Meagher et al.   BEHAVIOR GENETICS

Maternal separation with early weaning: a novel mouse model of early life neglect

(2010) Elizabeth D George et al.   BMC NEUROSCIENCE

Effects of maternal separation, early handling, and gonadal sex on regional metabolic capacity of the preweanling rat brain

(2010) Jaclyn M. Spivey et al.   BRAIN RESEARCH

Expression of Glucocorticoid Receptor and Early Growth Response Gene 1 during Postnatal Development of Two Inbred Strains of Mice Exposed to Early Life Stress

(2010) Sylvia Navailles et al.   DEVELOPMENTAL NEUROSCIENCE

Animal models of early life stress: Implications for understanding resilience

(2010) David M. Lyons et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Cohort Profile: The Amsterdam Born Children and their Development (ABCD) Study

(2010) M. van Eijsden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Early Life Stress Enhances Behavioral Vulnerability to Stress through the Activation of REST4-Mediated Gene Transcription in the Medial Prefrontal Cortex of Rodents

(2010) S. Uchida et al.   JOURNAL OF NEUROSCIENCE

Maternal warmth buffers the effects of low early-life socioeconomic status on pro-inflammatory signaling in adulthood

(2010) E Chen et al.   MOLECULAR PSYCHIATRY

The Effect of Early-Life Stress on Airway Inflammation in Adult Mice

(2010) Rattanjeet Vig et al.   NEUROIMMUNOMODULATION

Maternal separation produces, and a second separation enhances, core temperature and passive behavioral responses in guinea pig pups

(2010) Michael B. Hennessy et al.   PHYSIOLOGY & BEHAVIOR

Glucocorticoid Effects on the Programming of AT1b Angiotensin Receptor Gene Methylation and Expression in the Rat

(2010) Irina Bogdarina et al.   PLoS One

Early life stress paradigms in rodents: potential animal models of depression?

(2010) Mathias V. Schmidt et al.   PSYCHOPHARMACOLOGY

The relationship of adverse childhood experiences to a history of premature death of family members

(2009) Robert F Anda et al.   BMC PUBLIC HEALTH

Risk Factors for Abdominal Aortic Aneurysms

(2009) Signe Helene Forsdahl et al.   CIRCULATION

Developmental programming and hypertension

(2009) Anne Monique Nuyt et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Early Life Stress Sensitizes Rats to Angiotensin II–Induced Hypertension and Vascular Inflammation in Adult Life

(2009) Analia S. Loria et al.   HYPERTENSION

The Association of Anger and Hostility With Future Coronary Heart Disease

(2009) Yoichi Chida et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Dynamic DNA methylation programs persistent adverse effects of early-life stress

(2009) Chris Murgatroyd et al.   NATURE NEUROSCIENCE

A single exposure to social isolation in domestic piglets activates behavioural arousal, neuroendocrine stress hormones, and stress-related gene expression in the brain

(2009) E. Kanitz et al.   PHYSIOLOGY & BEHAVIOR

Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling

(2009) G. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiovascular health of Finnish war evacuees 60 years later

(2008) Hanna Alastalo et al.   ANNALS OF MEDICINE

Lifestyle and environmental factors associated with inflammation, oxidative stress and insulin resistance in children

(2008) Roya Kelishadi et al.   ATHEROSCLEROSIS

Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses

(2008) Siobhain M. O'Mahony et al.   BIOLOGICAL PSYCHIATRY

Differential development of stress system (re)activity at weaning dependent on time of disruption of maternal care

(2008) L. Enthoven et al.   BRAIN RESEARCH

Offspring birth weight, gestational age and maternal characteristics in relation to glucose status at age 53 years: evidence from a national birth cohort

(2008) D. Kuh et al.   DIABETIC MEDICINE

Hypothalamic-Pituitary-Adrenal Axis Activity of Newborn Mice Rapidly Desensitizes to Repeated Maternal Absence but Becomes Highly Responsive to Novelty

(2008) L. Enthoven et al.   ENDOCRINOLOGY

Postnatal Stress in Birds: A Novel Model of Glucocorticoid Programming of the Hypothalamic-Pituitary-Adrenal Axis

(2008) Karen A. Spencer et al.   ENDOCRINOLOGY

Sexually dimorphic effects of maternal separation stress on corticotrophin-releasing factor and vasopressin systems in the adult rat brain

(2008) Lieve Desbonnet et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Epigenetic Programming of Phenotypic Variations in Reproductive Strategies in the Rat Through Maternal Care

(2008) N. M. Cameron et al.   JOURNAL OF NEUROENDOCRINOLOGY

Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model

(2008) s. o'mahony et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mechanisms underlying developmental programming of elevated blood pressure and vascular dysfunction: evidence from human studies and experimental animal models

(2007) Anne Monique Nuyt   CLINICAL SCIENCE

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION