Differential activation of regions within the biceps brachii muscle during fatigue

Aim: To examine the occurrence of repeated differential activation between the heads of the biceps brachii muscle and its relation to fatigue prevention during a submaximal contraction. Methods: Thirty-nine subjects carried out an isometric contraction of elbow flexion at 25% of maximal voluntary contraction (MVC) until exhaustion. A grid of 13 by 10 electrodes was used to record surface electromyographic signals from both heads of the biceps brachii. The root-mean-square of signals recorded from electrodes located medially and laterally was used to analyse activation differences. Differential activation was defined as periods of 33% different activation level between the two heads of the biceps brachii muscle. Results: Differential muscle activation was demonstrated in 30 of 33 subjects with appropriate data quality. The frequency of differential activation increased from 4.9 to 6.6 min(-1) at the end of the contractions with no change in duration of the differential activations (about 1.4 s). Moreover, the frequency of differential activation was, in general, negatively correlated with time to exhaustion. Conclusion: The observed differential activation between the heads of the biceps brachii can be explained by an uneven distribution of synaptic input to the motor neurone pool. The findings of this study indicate that differential activation of regions within a muscle does not prevent fatigue at a contraction level of 25% of MVC.