Magnetic properties of encapsulated magnetite in PLGA nanospheres

In this study, the biocompatible magnetic fluid was encapsulated in biodegradable polymer PLGA (poly D,L/lactide-co-glycolide acid) by the nanoprecipitation method. We characterized these spheres in terms of morphology, magnetite content and magnetic properties. The results showed good encapsulation with magnetite content 22wt% and magnetization 3.4 mT. The transmission electron microscopy and scanning electron microscopy images showed that magnetic particles have almost a spherical shape with approximate size 250 nm. Infrared spectroscopy and thermo-gravimetric analysis measurements were used to confirm incorporation of magnetic particles into the PLGA polymer.