Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins

Biology and pharmacology of bombesin receptor subtype-3

(2013) Ishita D. Majumdar et al.   Current Opinion in Endocrinology Diabetes and Obesity

Functional classification of membrane transporters and channels based on filtered TM/non-TM amino acid composition

(2012) N. S. Schaadt et al.   BIOPOLYMERS

Three-Dimensional Structures of Membrane Proteins from Genomic Sequencing

(2012) Thomas A. Hopf et al.   CELL

Identification of voltage-gated potassium channel subfamilies from sequence information using support vector machine

(2012) Wei Chen et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Structure-based prediction of protein–protein interactions on a genome-wide scale

(2012) Qiangfeng Cliff Zhang et al.   NATURE

Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen

(2012) Stephanie C. Stotz et al.   PLoS One

Prediction of transporter targets using efficient RBF networks with PSSM profiles and biochemical properties

(2011) Shu-An Chen et al.   BIOINFORMATICS

Three-dimensional modeling of protein interactions and complexes is going ‘omics

(2011) Amelie Stein et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

HMMER web server: interactive sequence similarity searching

(2011) R. D. Finn et al.   NUCLEIC ACIDS RESEARCH

MEDELLER: homology-based coordinate generation for membrane proteins

(2010) Sebastian Kelm et al.   BIOINFORMATICS

Structural fragment clustering reveals novel structural and functional motifs in α-helical transmembrane proteins

(2010) Annalisa Marsico et al.   BMC BIOINFORMATICS

Large-scale prediction of protein-protein interactions from structures

(2010) Martial Hue et al.   BMC BIOINFORMATICS

A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

(2010) Eelke van der Horst et al.   BMC BIOINFORMATICS

Predicting ion channels and their types by the dipeptide mode of pseudo amino acid composition

(2010) Hao Lin et al.   JOURNAL OF THEORETICAL BIOLOGY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Prediction of the human membrane proteome

(2010) Linn Fagerberg et al.   PROTEOMICS

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Properties and identification of human protein drug targets

(2009) Tala M. Bakheet et al.   BIOINFORMATICS

TransportTP: A two-phase classification approach for membrane transporter prediction and characterization

(2009) Haiquan Li et al.   BMC BIOINFORMATICS

Transmembrane protein topology prediction using support vector machines

(2009) Timothy Nugent et al.   BMC BIOINFORMATICS

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Predict potential drug targets from the ion channel proteins based on SVM

(2009) Chen Huang et al.   JOURNAL OF THEORETICAL BIOLOGY

SLITHER: a web server for generating contiguous conformations of substrate molecules entering into deep active sites of proteins or migrating through channels in membrane transporters

(2009) P.-H. Lee et al.   NUCLEIC ACIDS RESEARCH

MeMotif: a database of linear motifs in α-helical transmembrane proteins

(2009) Annalisa Marsico et al.   NUCLEIC ACIDS RESEARCH

The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator

(2009) D. Fontanilla et al.   SCIENCE

Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter

(2009) D. Jiang et al.   SCIENCE

SPOCTOPUS: a combined predictor of signal peptides and membrane protein topology

(2008) Håkan Viklund et al.   BIOINFORMATICS

Functional discrimination of membrane proteins using machine learning techniques

(2008) M Michael Gromiha et al.   BMC BIOINFORMATICS

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

Classification of voltage-gated K+ ion channels from 3D pseudo-folding graph representation of protein sequences using genetic algorithm-optimized support vector machines

(2008) Michael Fernández et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

MolAxis: a server for identification of channels in macromolecules

(2008) Eitan Yaffe et al.   NUCLEIC ACIDS RESEARCH

Annotating Genes of Known and Unknown Function by Large-Scale Coexpression Analysis

(2008) K. Horan et al.   PLANT PHYSIOLOGY

Prediction of membrane-protein topology from first principles

(2008) A. Bernsel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE