Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

microRNAs in Stroke Pathogenesis

(2011) J. R. Tan et al.   CURRENT MOLECULAR MEDICINE

Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor Cells

(2011) Hongfu Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production

(2011) Alessandra Valerio et al.   JOURNAL OF NEUROCHEMISTRY

Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascades

(2011) Mei-Jen Wang et al.   Journal of Neuroinflammation

Neuroprotection by Valproic Acid in Mouse Models of Permanent and Transient Focal Cerebral Ischemia

(2011) Yong Ri Qian et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Mesenchymal Stem Cells Primed With Valproate and Lithium Robustly Migrate to Infarcted Regions and Facilitate Recovery in a Stroke Model

(2011) Li-Kai Tsai et al.   STROKE

GSK-3 as a Target for Lithium-Induced Neuroprotection Against Excitotoxicity in Neuronal Cultures and Animal Models of Ischemic Stroke

(2011) De-Maw Chuang et al.   Frontiers in Molecular Neuroscience

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition

(2010) Zhifei Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons

(2010) Zoya Marinova et al.   NEUROPHARMACOLOGY

The Mood Stabilizers Valproic Acid and Lithium Enhance Mesenchymal Stem Cell Migration via Distinct Mechanisms

(2010) Li-Kai Tsai et al.   NEUROPSYCHOPHARMACOLOGY

Lamotrigine increases the number of BrdU-labeled cellsinthe rat hippocampus

(2010) Daniel Kondziella et al.   NEUROREPORT

Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders

(2010) Chi-Tso Chiu et al.   PHARMACOLOGY & THERAPEUTICS

Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cells

(2010) Shuken Boku et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

(2010) Q Li et al.   Cell Death & Disease

Neurocognitive and Neuroimaging Predictors of Clinical Outcome in Bipolar Disorder

(2010) Carrie E. Bearden et al.   Current Psychiatry Reports

Calpains as a Target for Therapy of Neurodegenerative Diseases: Putative Role of Lithium

(2009) Antoni Camins et al.   CURRENT DRUG METABOLISM

Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells

(2009) Wei-Ching Huang et al.   IMMUNOLOGY

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

(2009) Zoya Marinova et al.   JOURNAL OF NEUROCHEMISTRY

The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain

(2009) Hyeon Ju Kim et al.   JOURNAL OF NEUROCHEMISTRY

Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain

(2009) Eléonore Beurel et al.   Journal of Neuroinflammation

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Plasma and Brain Matrix Metalloproteinase-9 After Acute Focal Cerebral Ischemia in Rats

(2009) Kyung-Pil Park et al.   STROKE

Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator

(2009) Gregory J. del Zoppo et al.   STROKE

Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9

(2009) Taura L. Barr et al.   STROKE

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Inhibition of GSK-3 reduces infarct volume and improves neurobehavioral functions

(2008) Seong-Ho Koh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vascular Endothelial Growth Factor and Angiopoietins in Neurovascular Regeneration and Protection Following Stroke

(2008) Tania Hansen et al.   CURRENT NEUROVASCULAR RESEARCH

Multiphasic roles for matrix metalloproteinases after stroke

(2008) A ROSELL et al.   CURRENT OPINION IN PHARMACOLOGY

Transient cerebral ischemia increases CA1 pyramidal neuron excitability

(2008) Yuan Fan et al.   EXPERIMENTAL NEUROLOGY

Synergistic Neuroprotective Effects of Lithium and Valproic Acid or Other Histone Deacetylase Inhibitors in Neurons: Roles of Glycogen Synthase Kinase-3 Inhibition

(2008) Y. Leng et al.   JOURNAL OF NEUROSCIENCE

A new penumbra: transitioning from injury into repair after stroke

(2008) Eng H Lo   NATURE MEDICINE

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

Chronic Administration of Mood Stabilizers Upregulates BDNF and Bcl-2 Expression Levels in Rat Frontal Cortex

(2008) Yunyoung C. Chang et al.   NEUROCHEMICAL RESEARCH

Evidence for Selective microRNAs and Their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers

(2008) Rulun Zhou et al.   NEUROPSYCHOPHARMACOLOGY

TREATMENT WITH THE GLYCOGEN SYNTHASE KINASE-3β INHIBITOR, TDZD-8, AFFECTS TRANSIENT CEREBRAL ISCHEMIA/REPERFUSION INJURY IN THE RAT HIPPOCAMPUS

(2008) Massimo Collino et al.   SHOCK

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE

National US Estimates of Recombinant Tissue Plasminogen Activator Use

(2008) Dawn Kleindorfer et al.   STROKE

MicroRNA Expression in the Blood and Brain of Rats Subjected to Transient Focal Ischemia by Middle Cerebral Artery Occlusion

(2008) Kandiah Jeyaseelan et al.   STROKE

Functional MRI of Delayed Chronic Lithium Treatment in Rat Focal Cerebral Ischemia

(2008) Young R. Kim et al.   STROKE

Lithium Upregulates Vascular Endothelial Growth Factor in Brain Endothelial Cells and Astrocytes

(2008) Shuzhen Guo et al.   STROKE

Lamotrigine attenuates cerebral vasospasm after experimental subarachnoid hemorrhage in rabbits

(2008) Hakan Seçkin et al.   SURGICAL NEUROLOGY

Opposing Actions of Phosphatidylinositol 3-Kinase and Glycogen Synthase Kinase-3β in the Regulation of HSF-1 Activity

(2003) Gautam N. Bijur et al.   JOURNAL OF NEUROCHEMISTRY