Metal ions, Alzheimer's disease and chelation therapy

Hydroxyquinoline based binders: Promising ligands for chelatotherapy?

(2010) Ana Budimir et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Biological metals and Alzheimer's disease: Implications for therapeutics and diagnostics

(2010) James A. Duce et al.   PROGRESS IN NEUROBIOLOGY

Aβ-mediated ROS production by Cu ions: Structural insights, mechanisms and relevance to Alzheimer's disease

(2009) Christelle Hureau et al.   BIOCHIMIE

Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer

(2009) Peter Faller   CHEMBIOCHEM

Medicinal Inorganic Chemistry Approaches to Passivation and Removal of Aberrant Metal Ions in Disease

(2009) Lauren E. Scott et al.   CHEMICAL REVIEWS

The chemistry of Alzheimer’s disease

(2009) Arvi Rauk   CHEMICAL SOCIETY REVIEWS

Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)

(2009) Henryk Kozlowski et al.   COORDINATION CHEMISTRY REVIEWS

Minding metals: Tailoring multifunctional chelating agents for neurodegenerative disease

(2009) Lissette R. Perez et al.   DALTON TRANSACTIONS

Low Micromolar Zinc Accelerates the Fibrillization of Human Tau via Bridging of Cys-291 and Cys-322

(2009) Zhong-Ying Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper in the brain and Alzheimer’s disease

(2009) Ya Hui Hung et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Alzheimer's disease, metal ions and metal homeostatic therapy

(2009) Paolo Zatta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

(2008) Lars Lannfelt et al.   LANCET NEUROLOGY

Free Copper, Ferroxidase and SOD1 Activities, Lipid Peroxidation and NO x Content in the CSF. A Different Marker Profile in Four Neurodegenerative Diseases

(2008) Marie-Catherine Boll et al.   NEUROCHEMICAL RESEARCH

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON

Therapeutics for Alzheimer’s disease based on the metal hypothesis

(2008) Ashley I. Bush et al.   Neurotherapeutics

Potential pathogenic role of β-amyloid1–42–aluminum complex in Alzheimer's disease

(2007) Denise Drago et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy

(2005) Alessandra Gaeta et al.   BRITISH JOURNAL OF PHARMACOLOGY