Article
Immunology
Eduardo Villamor, Mikael Norman, Stefan Johansson, Sven Cnattingius
Summary: This study found that maternal overweight and obesity severity are associated with an increased risk of EOS, especially in term infants. Half of the impact is mediated through preeclampsia, cesarean section delivery, and preterm delivery. A dose-response association was consistently present in term infants.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Denho Ravi, Erato Ntinopoulou, Nessim Guetta, Manuela Weier, Verena Vogel, Barbara Spellerberg, Parham Sendi, Sandrine Gremlich, Thierry Roger, Eric Giannoni
Summary: This study compares the response of newborn and adult macrophages to GBS. The findings show that newborn macrophages exhibit higher levels of cytokine release in response to GBS, and may play a significant role in the progression of GBS infection in newborns.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Gastroenterology & Hepatology
Hengjing Li, Daniel Boakye, Xuechen Chen, Lina Jansen, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner
Summary: Obesity during early adulthood is strongly associated with an increased risk of early-onset colorectal cancer, particularly among individuals who have not undergone colonoscopy.
Article
Medicine, General & Internal
Parco M. Siu, Angus P. Yu, Edwin C. Chin, Doris S. Yu, Stanley S. Hui, Jean Woo, Daniel Y. Fong, Gao X. Wei, Michael R. Irwin
Summary: Tai chi is an effective approach to reduce waist circumference in adults with central obesity aged 50 years or older. The study results showed positive changes in waist circumference, body weight, and blood lipid levels in both the tai chi group and exercise group compared to the control group.
ANNALS OF INTERNAL MEDICINE
(2021)
Review
Immunology
Konstantinos Karampatsas, Hannah Davies, Maren Mynarek, Nick Andrews, Paul T. Heath, Kirsty Le Doare
Summary: Prematurity/low birth weight and maternal colonization are major risk factors for late-onset Group B streptococcal infection. Future vaccine studies should identify the optimal time for vaccination during pregnancy to protect preterm infants.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Pharmacology & Pharmacy
Ou Wu, Jian Hang Leng, Fen Fang Yang, Hu Zhang, Xing Yu Zhang, Jia Jia Li, Xi Lu
Summary: The study found that serum resistin levels were significantly correlated with the onset and development of obesity-related hypertension, suggesting a potential role that may be more important than previously assumed. Further investigation into pathway substances in the early onset of obesity-related hypertension is warranted.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Public, Environmental & Occupational Health
Ziyaad Dangor, Anna C. Seale, Vuyelwa Baba, Gaurav Kwatra
Summary: Invasive group B streptococcal (GBS) disease is a significant problem in newborns, especially in African countries where preventive strategies are limited. The high mortality and serious neurodevelopmental impairments caused by GBS emphasize the need for a maternal vaccine. Ongoing clinical trials are evaluating the safety and efficacy of hexavalent polysaccharide protein conjugate and Alpha family surface protein vaccines.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Yan Cheng, Huilan Xu, Chris Rissel, Philayrath Phongsavan, Limin Buchanan, Sarah Taki, Alison Hayes, Louise A. Baur, Li Ming Wen
Summary: This study aimed to evaluate the feasibility of using correction modeling to improve the accuracy of mother-reported child height and weight at 2 years. Correction modeling for BMI was conducted, and the indirect correction method showed better prediction of overweight status and agreement with measured values compared to the mother-reported measures.
SCIENTIFIC REPORTS
(2022)
Article
Nutrition & Dietetics
Ulku Gul Siraz, Nihal Hatipoglu, M. Mumtaz Mazicioglu, Ahmet Ozturk, Betul Cicek, Selim Kurtoglu
Summary: According to this study, triponderal mass index (TMI) is as effective as body mass index (BMI) in determining obesity and body adiposity. The study developed TMI reference values for Turkish children and adolescents and compared TMI with BMI in terms of body adiposity and obesity indices, finding similar predictive power for both measurements.
Article
Pharmacology & Pharmacy
Ou Wu, Jian Hang Leng, Xingyu Zhang, Wei Liu, Fen Fang Yang, Hu Zhang, Jia Jia Li, Guo Zhong Zhang, Xi Lu
Summary: Leptin may not be essential but play an additive effect in the development of obesity-associated hypertension. Leptin may only play an additive effect role in the intricate interwoven network of regulators contributing to the development of hypertension in obese patients.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2022)
Article
Nutrition & Dietetics
Xiaolan Ying, Jie Lin, Shuhua Yuan, Chunhong Pan, Wenfang Dong, Jing Zhang, Lei Zhang, Jilei Lin, Yong Yin, Jinhong Wu
Summary: This study investigates the impact of overweight/obesity on pulmonary function in pediatric patients with new-onset asthma. The findings suggest that obesity may impair pulmonary function and increase the severity of asthma in overweight/obese individuals. While allergic inflammation plays a role in asthma onset, nonallergic inflammation may contribute to its severity in overweight/obese patients.
Article
Endocrinology & Metabolism
Siok Siong Ching, Phong Ching Lee, Chin Hong Lim, Andrew Siang Yih Wong, Annalisa Ya-Lyn Ng, Jinlin Lin, June Lee
Summary: This study aimed to validate the recently introduced metric %AWL for comparing outcomes after laparoscopic sleeve gastrectomy (LSG) and Roux-en-Y gastric bypass (LRYGB). The weight data of patients who had undergone LSG and LRYGB were analyzed, and %EWL, %TWL, and %AWL metrics were used for comparing their weight loss. The findings suggest that %AWL is the best metric for medium-term comparison after LRYGB, while an intermediary metric based on BMI 8 kg/m(2) provides the best fit for LSG.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Transplantation
Gabriel C. Oniscu, Daniel Abramowicz, Davide Bolignano, Ilaria Gandolfini, Rachel Hellemans, Umberto Maggiore, Ionut Nistor, Stephen O'Neill, Mehmet Sukru Sever, Muguet Koobasi, Evi Nagler
Summary: The clinical practice guideline Management of Obesity in Kidney Transplant Candidates and Recipients provides recommendations for addressing obesity in individuals with end-stage kidney disease, emphasizing shared decision-making and evidence-based treatment approaches following systematic reviews.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Nutrition & Dietetics
Maria Mantzorou, Dimitrios Papandreou, Georgios K. Vasios, Eleni Pavlidou, Georgios Antasouras, Evmorfia Psara, Zainab Taha, Efthymios Poulios, Constantinos Giaginis
Summary: Breastfeeding plays an important role in preventing obesity and reducing long-term negative health outcomes for both mothers and children.
Article
Public, Environmental & Occupational Health
Jinlei Li, Prajakta Joshi, Ting Fang Alvin Ang, Chunyu Liu, Sanford Auerbach, Sherral Devine, Rhoda Au
Summary: This study found a complex relationship between BMI and dementia risk, with the association potentially showing different patterns as individuals age. Monitoring BMI at different ages could help mitigate the risk of dementia over a person's lifetime.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2021)
