Article
Ophthalmology
Amy Logan, Andrew D. Pucker, Quentin Franklin, Gerald McGwin, Catherine Hogan, Laurel R. Kelley, Mike Christensen, Randy Brafford, Chris Lievens
Summary: The purpose of this study was to compare the ocular comfort of 0.7% olopatadine drops and 0.035% ketotifen fumarate drops. The results showed that the 0.7% olopatadine drops were more comfortable than the 0.035% ketotifen fumarate drops at all time-points.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Medicine, General & Internal
Minjie Chen, Bilian Ke, Jun Zou, Lan Gong, Yan Wang, Chaoran Zhang, Jianjiang Xu, Anji Wei, Jiaxu Hong
Summary: Both the isolated use of fluorometholone and combined use of azelastine and fluorometholone are effective in alleviating the signs and symptoms of severe ACD, but optimal response can be achieved with adjunctive treatment including azelastine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Usman Attique, Muhammad Tariq Khan, Irfan Aslam, Ahmed Usman
Summary: This study compared the efficacy of Olopatadine and Ketotifen ophthalmic solution in relieving itching in allergic conjunctivitis in Peshawar, Pakistan. The results showed that Olopatadine had a higher efficacy in relieving itching symptoms.
GOMAL JOURNAL OF MEDICAL SCIENCES
(2022)
Article
Allergy
Shiyu Li, Shenquan Zhong
Summary: Allergic conjunctivitis is a common inflammatory disease. This meta-analysis compares the efficacy of olopatadine and ketotifen for the treatment of allergic conjunctivitis. The results suggest that olopatadine may be more effective than ketotifen in reducing hyperaemia, but has no significant impact on itching, tearing or papillae.
POSTEPY DERMATOLOGII I ALERGOLOGII
(2023)
Article
Immunology
Rui Tang, Shubin Lei, Liping Zhu, Yuzhen Lv, Hong Li
Summary: This study aimed to evaluate the preventative efficacy of omalizumab for seasonal allergic rhinoconjunctivitis (SARC) and explore its influencing factors. The retrospective analysis of patients' medical records found that pre-seasonal omalizumab treatment could significantly alleviate SARC-related symptoms and reduce medication use. The dosage and number of injections of omalizumab did not affect the preventative efficacy, with a single dose of 150mg achieving satisfactory outcomes.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Engineering, Chemical
Anna Gumieniczek, Izabela Kozak, Pawel Zmudzki, Urszula Hubicka
Summary: The evaluation of pH-dependent reactivity of three antihistaminic drugs, ketotifen, epinastine and emedastine, showed variation in stability levels under different pH conditions. The study demonstrated the degradation rates and kinetics of the drugs, suggesting important implications for drug manufacturing and administration to patients.
Article
Allergy
Frederic de Blay, Alina Gherasim, Nathalie Domis, Ibrahim Choual, Tristan Bourcier
Summary: This study compared the efficacy of topical mast cell stabilizer and topical corticosteroids in exposure to airborne allergens. The results showed that the topical mast cell stabilizer was non-inferior to the topical corticosteroids in terms of the amount of allergen required to trigger a conjunctival response and the occurrence of adverse events. The environmental exposure chamber was an effective model for simulating real-life airborne allergen exposure.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Review
Pharmacology & Pharmacy
Lauren Lim, Melissa Lipari, Pramodini Kale-Pradhan
Summary: This review examined the pharmacology, efficacy, and safety of intranasal olopatadine hydrochloride-mometasone furoate (OM) combination in the treatment of seasonal allergic rhinitis (SAR). The results showed that OM significantly improves SAR symptoms and may be a viable option for short-term SAR treatment.
ANNALS OF PHARMACOTHERAPY
(2023)
Review
Ophthalmology
Xin-Yan Dou, Wei Zhang
Summary: A Meta-analysis of eight randomized controlled trials showed that topical ketotifen is an effective treatment for allergic conjunctivitis, reducing itching, tearing, and overall symptoms.
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Medicine, Research & Experimental
Atsuki Fukushima, Dai Miyazaki, Hirotsugu Kishimoto, Nobuyuki Ebihara
Summary: The study evaluated the effectiveness of proactive and as-needed use of antihistamine eye drops in controlling symptoms and found that proactive use can improve quality of life (QOL).
ADVANCES IN THERAPY
(2022)
Article
Veterinary Sciences
Esther T. Mamo, Georgina M. Newbold, Shelby C. Moorehead
Summary: The study demonstrated that 0.7% olopatadine hydrochloride may be beneficial in prophylaxis for reducing the severity and duration of clinical signs of allergic conjunctivitis in dogs, particularly chemosis. However, there was no difference in the maximum overall conjunctival scores between different experimental phases and treatment groups.
VETERINARY OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Shruti Ayyappanavar, Sriya Sridhar, Kiran Kumar, C. R. Jayanthi, Suresh Babu Gangasagara, B. L. Sujatha Rathod, B. Preethi, Preeti Mittal
Summary: A comparative study of 180 patients with mild to moderate allergic conjunctivitis showed that Alcaftadine, Olopatadine, and Bepotastine ophthalmic solutions were all effective in resolving symptoms. However, Bepotastine and Alcaftadine were found to be more effective than Olopatadine in alleviating the symptoms of allergic conjunctivitis.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Otorhinolaryngology
Jiayi Yang, Weidong Wang, Zhen Shen, Wei Kang, Pengfei Zhang, Xin Chen, Huajing Li, Yuan Shao, Lifeng Liu, Shaoqiang Zhang, Fang Quan
Summary: This study investigates the efficacy and safety of sublingual immunotherapy (SLIT) with A. annua allergens in patients with seasonal allergic rhinoconjunctivitis over two pollen seasons. The results show that the symptoms and medication scores of the SLIT group decreased in 2021 and remained lower than the baseline in 2022. Compared with the SLIT group, the control group showed significant improvement in efficacy indexes in 2022. Therefore, A. annua-SLIT can safely and effectively treat patients with moderate-severe seasonal allergic rhinoconjunctivitis over two pollen seasons.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Allergy
Jiayu Bao, Lei Tian, Yifan Meng, Binge Wu, Jingyi Wang, Jing He, Qiyan Shao, Chengshuo Wang, Ying Jie, Luo Zhang
Summary: Measuring the total IgE level in tears can accurately assess the severity and predict the prognosis of seasonal allergic conjunctivitis (SAC).
CLINICAL AND TRANSLATIONAL ALLERGY
(2022)
Article
Medicine, Research & Experimental
Limei Liu, Jiaomin Yang, Wuguang Ji, Chao Wang
Summary: This study found significant morphological and cytological changes in the meibomian gland (MG) of patients with seasonal allergic conjunctivitis (SAC), indicating abnormal tear film function in these patients. The use of the Keratograph 5M system and laser scanning confocal microscopy (LSCM) were effective methods for evaluating MG status and ocular surface diseases.
MEDICAL SCIENCE MONITOR
(2022)
Article
Otorhinolaryngology
Elif Koclu Hetemoglu, Seda Turkoglu Babakurban, Yunus Kasim Terzi, Feride Iffet Sahin, Selim Sermed Erbek
AURIS NASUS LARYNX
(2019)
Article
Surgery
Ozan Erol, Fuat Buyuklu, Alper Koycu, Ceren Bas, Selim S. Erbek
AESTHETIC PLASTIC SURGERY
(2019)
Article
Biochemistry & Molecular Biology
Serhat Inan, Seda Turkoglu Babakurban, Selim Sermed Erbek, Yunus Kasim Terzi, Feride Iffet Sahin
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
(2020)
Article
Surgery
Ozan Erol, Fuat Buyuklu, Alper Koycu, Sabuhi Jafarov, Goknil Gultekin, Selim S. Erbek
AESTHETIC PLASTIC SURGERY
(2020)
Article
Public, Environmental & Occupational Health
Buse Budak, Kubra Coban, Selim S. Erbek
Summary: The study showed that carpenters have a significantly higher risk of noise-induced hearing loss compared to the control group, with lower emission values at 2000 and 2800 Hz in both ears.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2021)
Article
Otorhinolaryngology
Belde Culhaoglu, Selim S. Erbek, Deniz Anuk Ince, Ayse Nur Ecevit, Seyra Erbek
Summary: This study compared the integrity of the efferent auditory pathways between newborns with high hyperbilirubinemia levels and healthy newborns, and found that high hyperbilirubinemia may have a disruptive effect on the efferent auditory system in newborns. Additionally, a MOC suppression test could be useful in addition to hearing screening for at-risk newborn infants.
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
(2021)
Article
Medicine, General & Internal
Fatmanur Uysal, Selim S. Erbek, Seyra Erbek, Belde Culhaoglu
Summary: The study investigated the effect of Tacrolimus on the inner ear of rats, and the results indicated that Tacrolimus does not have ototoxic effects on the auditory system of rats considering the administered dosage and time.
CUKUROVA MEDICAL JOURNAL
(2022)
Article
Otorhinolaryngology
Alper Koycu, Ceren Bas, Ugur H. Musabak, Selim Sermed Erbek, Huseyin Samet Koca, Seda Turkoglu Babakurban, Melike Bahcecitapar
Summary: This study investigated the effects of visible light-infrared light phototherapy on clinical improvements and cytologic effects in patients with allergic rhinitis. The results suggest that this treatment can improve symptoms in patients with allergic rhinitis.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2023)
Article
Medicine, General & Internal
Fulya Ozer, Goezde Bayramoglu Cabuk, Meryem Mutlu, Serap Er, Agit Simsek, Selim Sermed Erbek
Summary: This study aimed to analyze the factors affecting tinnitus severity in the population aged 60 and over using multi-central data and multivariate analysis. The results showed that tinnitus loudness increased significantly in the group over the age of 79, and high education level and advanced age over 79 were determined as independent risk factors that increased tinnitus severity.
GAZI MEDICAL JOURNAL
(2023)
Article
Otorhinolaryngology
Berk Baytaroglu, Sabuhi Jafarov, Selim Sermed Erbek
Summary: The study found that middle ear resonance frequency values were not affected in postmenopausal osteoporosis patients, but there was greater sensorineural hearing loss in females with postmenopausal osteoporosis compared to healthy postmenopausal females.
JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY
(2021)
Article
Otorhinolaryngology
Mehbube Tuncer, Kubra Coban, Selim S. Erbek, H. Seyra Erbek
Summary: The study found that patients with fibromyalgia syndrome have impaired audiovestibular functions, including decreased pure-tone hearing thresholds and inability to obtain ocular and cervical vestibular-evoked myogenic potentials.
JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY
(2021)
Article
Otorhinolaryngology
Serhat Inan, Fulya Ozer, Selim Sermed Erbek, Fatma Caylakli, Ilker Odemis, Ebru Kursun
Summary: This study aimed to evaluate olfactory disorders and recovery processes in patients with COVID-19 within one month from diagnosis. Results showed that a majority of patients experienced olfactory disorders during the infection period, with anosmia and hyposmia being common symptoms, adversely affecting their quality of life.
Article
Allergy
Isilay Oz, Sibel Ozdas, Sibel Bastimur, Talih Ozdas, Sami Engin Muz, Huntuk Atilla, Kenan Kurt, Selim Erbek
ASTIM ALLERJI IMMUNOLOJI
(2020)
Article
Otorhinolaryngology
Emine Demirel Aksoy, Belde Culhaoglu, F. Ceyda Akin Ocal, Seim Sermed Erbek, Hatice Seyra Erbek
TURKISH ARCHIVES OF OTORHINOLARYNGOLOGY
(2019)
Article
Otorhinolaryngology
Seyra Erbek, Alper Koycu, G. Gulsah Polat, Selim S. Erbek