Article
Surgery
Flavius-Stefan Marin, Einas Abou Ali, Arthur Belle, Frederic Beuvon, Romain Coriat, Stanislas Chaussade
Summary: A new endoscopic technique has been designed for the resection of highly suspicious deep submucosal invasion rectal carcinoma, which can overcome the limitations of surgical resection and other endoscopic treatments.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Oncology
Xiaoyu Xiong, Chao Wang, Bo Wang, Zhanlong Shen, Kewei Jiang, Zhidong Gao, Yingjiang Ye
Summary: A meta-analysis of 12 studies involving 3526 patients showed that compared to radical surgery (RS), transanal endoscopic microsurgery (TEM) has advantages in terms of operative time, intraoperative blood loss, perioperative mortality, and postoperative surgical complications. However, TEM is associated with higher risks of positive margin, local recurrence, and overall recurrence.
SURGICAL ONCOLOGY-OXFORD
(2021)
Article
Gastroenterology & Hepatology
Liu Ran, Yan Chuanwang, Shang Wei, Yuan Wenguang, Hao Liang, Zhai Jiancheng, Li Wen, Yang Hui, Xia Lijian
Summary: A circumferential extent of mucosal defect >3/4 was identified as the only independent risk factor for stenosis in treating rectal adenoma and early cancer with TEM. Incision of the stenosis ring using the TEM platform is an effective strategy for treating stenosis.
COLORECTAL DISEASE
(2022)
Article
Endocrinology & Metabolism
Rui Jin, Xiaoyin Bai, Tianming Xu, Xi Wu, Qipu Wang, Jingnan Li
Summary: This study evaluated the efficacy of endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM) in the treatment of rectal neuroendocrine tumors (NETs) ≤ 2 cm. The results showed that although the complete resection rate was higher in the TEM group than in the ESD group, there was no difference in recurrence rates between the two modalities during long-term follow-up.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Gastroenterology & Hepatology
Cintia Mayumi Sakurai Kimura, Fabio Shiguehissa Kawaguti, Caio Sergio Rizkallah Nahas, Carlos Frederico Sparapan Marques, Vanderlei Segatelli, Bruno Costa Martins, Gustavo Andrade de Paulo, Ivan Cecconello, Ulysses Ribeiro-Junior, Sergio Carlos Nahas, Fauze Maluf-Filho
Summary: A retrospective single-center study on 98 consecutive procedures revealed that endoscopic submucosal resection appears to have advantages over transanal endoscopic microsurgery in terms of similar en bloc resection rate and lower rates of late complications and recurrences. Multicenter randomized controlled trials are recommended to further support these findings.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Gastroenterology & Hepatology
Wei Li, Xing Xing Xiang, Hong Da Wang, Chen Jun Cai, Ying Hao Cao, Tao Liu
Summary: Through the analysis of 13 studies, it was found that transanal endoscopic microsurgery and radical surgery adhering to total mesorectal excision have similar safety and treatment outcomes in the treatment of early-stage rectal cancer. However, significant differences were observed in perioperative mortality, local recurrence, overall survival, disease-free survival, temporary stoma, permanent stoma, postoperative complications, rectal pain, operation time, blood loss, and time of hospitalization.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Gastroenterology & Hepatology
Sung Sil Park, Byung Chang Kim, Dong-eun Lee, Kyung Su Han, Bun Kim, Chang Won Hong, Dae Kyung Sohn
Summary: This study compared the efficacy and safety of ESD and TEM for rectal NETs <= 20 mm, finding that while TEM had a higher R0 resection rate, ESD had shorter procedure and hospital stay times, particularly suitable for rectal NETs <10 mm.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Kiran Altaf, Simone Slawik, Dana Sochorova, Sukhpreet Gahunia, Timothy Andrews, Ashley Kehoe, Shakil Ahmed
Summary: This study examined the long-term outcomes and continence of patients undergoing rectal defect management after TEM. There were no significant differences in short-term complications between the open and closed defect groups, but a significant worsening in continence was observed in the closed group after scar healing.
COLORECTAL DISEASE
(2021)
Article
Surgery
Katarina Levic Souzani, Orhan Bulut, Tine Plato Kuhlmann, Ismail Gogenur, Thue Bisgaard
Summary: This study found no difference in postoperative short- or long-term outcomes between cTME and pTME in patients with rectal cancer, although patients undergoing cTME experienced more intraoperative complications.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Wei-Kun Shi, Rui Hou, Yun-Hao Li, Xiao-Yuan Qiu, Yu-Xin Liu, Bin Wu, Yi Xiao, Jiao-Lin Zhou, Guo-Le Lin
Summary: This study assessed the efficacy and safety of transanal endoscopic microsurgery (TEM) in the treatment of rectal neuroendocrine tumors (RNET). The results showed that TEM has satisfactory long-term outcomes and relatively low anal function disturbance for small RNET.
Article
Surgery
Xueshan Bai, Weixun Zhou, Yunhao Li, Guole Lin
Summary: This study evaluated the management and outcome of patients with localized rectal GIST undergoing TEM with neoadjuvant imatinib therapy. The results showed that neoadjuvant imatinib significantly reduced tumor size, enabling sphincter-preserving surgery in 16 patients and achieving complete resection in all patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Garrett G. R. J. Johnson, Reagan L. Robertson, Ashley Vergis, Manoj Raval, Terry Phang, Ahmer Karimuddin, Carl Brown
Summary: Transanal endoscopic surgery as the sole surgical treatment for T2 and T3 rectal cancer has compromised oncologic outcomes. However, it remains an option for patients who decline radical resection.
DISEASES OF THE COLON & RECTUM
(2023)
Article
Oncology
Mingqing Zhang, Yongdan Zhang, Haoren Jing, Lizhong Zhao, Mingyue Xu, Hui Xu, Siwei Zhu, Xipeng Zhang
Summary: This single-center study reports the prognosis of early rectal cancer patients over 60 years old after TEM. The 5-year progression-free survival rate was lower in the high-risk patients group than in the non-high-risk patients group, but there was no statistically significant difference. There was also no significant difference in DFS and OS between patients over and under 70 years old.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Katerina Neumann, Nirmal Randhawa, Jason Park, David J. Hochman
Summary: TEM for rectal neoplasm is associated with significantly lower hospital costs, which far outweigh the costs of acquiring and maintaining the technology.
Article
Surgery
Kang Xu, Yulin Liu, Peng Yu, Wei Shang, Yongbo Zhang, Mingwen Jiao, Zhonghui Cui, Lijian Xia, Jingbo Chen
Summary: Adjuvant chemoradiotherapy after TEM may be an alternative for high-risk pT1 and T2 rectal cancer patients who are not suitable or unwilling to undergo salvage radical surgery, as suggested by our study.
JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES
(2021)
