Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway

NFAT transcription factor regulation by urocortin II in cardiac myocytes and heart failure

(2014) Stefanie Walther et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells

(2014) Guozhu Chen et al.   APOPTOSIS

Insights Into the Activation and Inhibition of Angiotensin II Type 1 Receptor in the Mechanically Loaded Heart

(2014) Jian Wu et al.   CIRCULATION JOURNAL

Non-coding RNAs in Cardiac Remodeling and Heart Failure

(2013) Regalla Kumarswamy et al.   CIRCULATION RESEARCH

Identification of cathepsin B in the razor clam Sinonovacula constricta and its role in innate immune responses

(2013) Donghong Niu et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Caspase-3 as a therapeutic target for heart failure

(2013) Bo Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cathepsin B as a cancer target

(2013) Christopher S Gondi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Administration of cathepsin B inhibitor CA-074Me reduces inflammation and apoptosis in polymyositis

(2013) Yurong Feng et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Decoding cell death signals in liver inflammation

(2013) Catherine Brenner et al.   JOURNAL OF HEPATOLOGY

Cathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway

(2013) AIGUO LIU et al.   Molecular Medicine Reports

Matrix metalloproteinase (MMP)-9: A proximal biomarker for cardiac remodeling and a distal biomarker for inflammation

(2013) Ganesh V. Halade et al.   PHARMACOLOGY & THERAPEUTICS

Cathepsin B Is Up-Regulated and Mediates Extracellular Matrix Degradation in Trabecular Meshwork Cells Following Phagocytic Challenge

(2013) Kristine Porter et al.   PLoS One

Role of α-crystallin B as a regulatory switch in modulating cardiomyocyte apoptosis by mitochondria or endoplasmic reticulum during cardiac hypertrophy and myocardial infarction

(2013) A Mitra et al.   Cell Death & Disease

Cathepsin‐L Ameliorates Cardiac Hypertrophy Through Activation of the Autophagy–Lysosomal Dependent Protein Processing Pathways

(2013) Mei Sun et al.   Journal of the American Heart Association

Both Internalization and AIP1 Association Are Required for Tumor Necrosis Factor Receptor 2-Mediated JNK Signaling

(2012) Weidong Ji et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Dual Role for Glucocorticoids in Cardiomyocyte Hypertrophy and Apoptosis

(2012) Rongqin Ren et al.   ENDOCRINOLOGY

Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

(2011) Ling Yan et al.   CARDIOVASCULAR RESEARCH

Phosphoinositide-3 Kinase Signaling in Cardiac Hypertrophy and Heart Failure

(2011) Toshinori Aoyagi et al.   CURRENT PHARMACEUTICAL DESIGN

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Role of various proteases in cardiac remodeling and progression of heart failure

(2011) Alison L. Müller et al.   HEART FAILURE REVIEWS

Cardiac remodeling at the population level—risk factors, screening and outcomes

(2011) Ola Gjesdal et al.   Nature Reviews Cardiology

Endogenous HMGB1 contributes to ischemia-reperfusion-induced myocardial apoptosis by potentiating the effect of TNF-α/JNK

(2010) Hu Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cathepsin B facilitates autophagy-mediated apoptosis in SPARC overexpressed primitive neuroectodermal tumor cells

(2010) P Bhoopathi et al.   CELL DEATH AND DIFFERENTIATION

Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure

(2009) Xiao-Mei Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cardiomyopathy is associated with structural remodelling of heart valve extracellular matrix

(2009) Katja Schenke-Layland et al.   EUROPEAN HEART JOURNAL

Molecular targets and regulators of cardiac hypertrophy

(2009) Agrawal Rohini et al.   PHARMACOLOGICAL RESEARCH

Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential

(2008) Anna Moles et al.   HEPATOLOGY

Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3β signaling

(2008) Qizhu Tang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM