Partial deletion of ROCK2 protects mice from high-fat diet-induced cardiac insulin resistance and contractile dysfunction

Does the metabolic syndrome impact left-ventricular mechanics? A two-dimensional speckle tracking study

(2014) Marijana Tadic et al.   JOURNAL OF HYPERTENSION

ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance

(2013) Seung-Hwan Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity

(2013) T Pulinilkunnil et al.   INTERNATIONAL JOURNAL OF OBESITY

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart

(2013) Christian Riehle et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-1 Increases PTEN Phosphatase Activity While Decreasing PTEN Protein Stability by Inhibiting Casein Kinase 2

(2013) Nikolaos Patsoukis et al.   MOLECULAR AND CELLULAR BIOLOGY

Myocardial deformation and twist mechanics in adults with metabolic syndrome: Impact of cumulative metabolic burden

(2013) Edward Crendal et al.   Obesity

High Fat Feeding in Mice Is Insufficient to Induce Cardiac Dysfunction and Does Not Exacerbate Heart Failure

(2013) Robert E. Brainard et al.   PLoS One

Diabetes-induced increased oxidative stress in cardiomyocytes is sustained by a positive feedback loop involving Rho kinase and PKCβ2

(2012) Hesham Soliman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Insulin Resistance: Metabolic Mechanisms and Consequences in the Heart

(2012) E. Dale Abel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GLUT4 content decreases along with insulin resistance and high levels of inflammatory markers in rats with metabolic syndrome

(2012) Natalia M Leguisamo et al.   Cardiovascular Diabetology

Wip1-Dependent Regulation of Autophagy, Obesity, and Atherosclerosis

(2012) Xavier Le Guezennec et al.   Cell Metabolism

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Regulation of Glucose Transport by ROCK1 Differs from That of ROCK2 and Is Controlled by Actin Polymerization

(2012) Kwang-Hoon Chun et al.   ENDOCRINOLOGY

A perspective on obesity cardiomyopathy

(2012) Tendoh Timoh et al.   Obesity Research & Clinical Practice

New approaches in small animal echocardiography: imaging the sounds of silence

(2011) Rashmi Ram et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Obesity Stresses Cardiac Mitochondria Even When You Are Young⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.

(2011) E. Dale Abel   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Obesity Induces Signs of Premature Cardiac Aging in Younger Patients

(2011) Bernd Niemann et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Multiple abnormalities of myocardial insulin signaling in a porcine model of diet-induced obesity

(2009) Jenny Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding

(2009) Jordan J. Wright et al.   CARDIOVASCULAR RESEARCH

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

(2009) Sihem Boudina et al.   CIRCULATION

Thromboxane A2Receptor Activates a Rho-associated Kinase/LKB1/PTEN Pathway to Attenuate Endothelium Insulin Signaling

(2009) Ping Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted Disruption of ROCK1 Causes Insulin Resistancein Vivo

(2009) Dae Ho Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Rho Kinase Isoforms in Lung Endothelial Cells during Inflammation

(2009) P. Y. Mong et al.   JOURNAL OF IMMUNOLOGY

Insulin signalling in the heart

(2008) L. Bertrand et al.   CARDIOVASCULAR RESEARCH

Myocardial involvement during the early course of type 2 diabetes mellitus: usefulness of Myocardial Performance Index

(2008) Paolo Pattoneri et al.   Cardiovascular Ultrasound

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

(2008) Tae-Sik Park et al.   JOURNAL OF LIPID RESEARCH

Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy

(2008) Jianjian Shi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A critical role of Rho-kinase ROCK2 in the regulation of spine and synaptic function

(2008) Zikai Zhou et al.   NEUROPHARMACOLOGY