Overexpression of PAK1 Promotes Cell Survival in Inflammatory Bowel Diseases and Colitis-associated Cancer

Tu1674 PAK1 Mediates NF-KB Signaling in Colitis and Colitis-Associated Cancer

(2015) Kyle W. Dammann et al.   GASTROENTEROLOGY

p21-activated kinase 1: PAK’ed with potential

(2015) Christy Ong et al.   Oncotarget

Tracing PAKs from GI inflammation to cancer

(2014) Kyle Dammann et al.   GUT

p-21-Activated kinase 1 mediates gastrin-stimulated proliferation in the colorectal mucosa via multiple signaling pathways

(2013) Nhi Huynh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells

(2013) Vineeta Khare et al.   BIOCHEMICAL PHARMACOLOGY

Antioxidant Properties of Mesalamine in Colitis Inhibit Phosphoinositide 3-Kinase Signaling in Progenitor Cells

(2013) Elizabeth Managlia et al.   INFLAMMATORY BOWEL DISEASES

Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity

(2012) Mee-Hee Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1

(2012) Vineeta Khare et al.   BIOCHEMICAL PHARMACOLOGY

Molecular Pathways: Targeting P21-Activated Kinase 1 Signaling in Cancer--Opportunities, Challenges, and Limitations

(2012) J. Eswaran et al.   CLINICAL CANCER RESEARCH

Interaction of Mesalasine (5-ASA) with Translational Initiation Factors eIF4 Partially Explains 5-ASA Anti-Inflammatory and Anti-Neoplastic Activities

(2012) Alex Lyakhovich et al.   Medicinal Chemistry

MSH3-Deficiency Initiates EMAST without Oncogenic Transformation of Human Colon Epithelial Cells

(2012) Christoph Campregher et al.   PLoS One

PAK1-dependent MAPK pathway activation is required for colorectal cancer cell proliferation

(2012) Haitao Qing et al.   TUMOR BIOLOGY

P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth

(2011) Hong He et al.   CANCER LETTERS

Single Nucleotide Polymorphisms That Increase Expression of the Guanosine Triphosphatase RAC1 Are Associated With Ulcerative Colitis

(2011) Aleixo M. Muise et al.   GASTROENTEROLOGY

5-aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer

(2011) Bart Baan et al.   GUT

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways

(2010) Nhi Huynh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PAK1 interacts with β-catenin and is required for the regulation of the β-catenin signalling pathway by gastrins

(2008) Hong He et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH