Article
Nutrition & Dietetics
Xin Xu, Hua-Yong Du, Zuliyaer Talifu, Chun-Jia Zhang, Ze-Hui Li, Wu-Bo Liu, Yi-Xiong Liang, Xu-Luan Xu, Jin-Ming Zhang, De-Gang Yang, Feng Gao, Liang-Jie Du, Yan Yu, Ying-Li Jing, Jian-Jun Li
Summary: The combination of BWSTT and GlyNAC has neuroprotective effects, promotes motor function recovery, and delays skeletal muscle atrophy in rats with SCI. GlyNAC alone improves motor function, but the combination with BWSTT is more effective.
Article
Orthopedics
Wenyao Yang, Bimin Gao, Ling Qin, Xinluan Wang
Summary: Puerarin treatment improved skeletal muscle strength and contraction function in young adult rats, possibly by regulating gut microbiota to increase short-chain fatty acid production and enhance ATP synthesis.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2022)
Article
Agriculture, Dairy & Animal Science
Nicolas Busse, Madison L. Gonzalez, Mackenzie L. Krason, Sally E. Johnson
Summary: Consumption of HMB increased the percentage of type IIA and IIA/X muscle fibers in the GM, but did not improve athletic performance in horses. Additionally, HMB supplementation did not have measurable effects on the biomechanical properties of the muscles in horses.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Geriatrics & Gerontology
Natany G. Reis, Ana P. Assis, Natalia Lautherbach, Dawit A. Goncalves, Wilian A. Silveira, Henrique J. N. Morgan, Rafael R. Valentim, Lucas F. Almeida, Lilian C. Heck, Neusa M. Zanon, Tatiana E. Koike, Audrei R. Santos, Elen H. Miyabara, Isis C. Kettelhut, Luiz C. Navegantes
Summary: This study found that maternal vitamin D deficiency selectively affects the development of type-II muscle fibers in male offspring rats, leading to muscle atrophy. However, compensatory increase in vitamin D content in adult age may increase fiber size and fatigue resistance.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Medicine, Research & Experimental
Lin Yin, Xi Chen, Na Li, Weihua Jia, Nuoqi Wang, Biyu Hou, Haiguang Yang, Li Zhang, Guifen Qiang, Xiuying Yang, Guanhua Du
Summary: The study showed that puerarin can alleviate skeletal muscle wasting in type 1 diabetes rats by promoting muscle strength and weight increase, as well as inhibiting muscle wasting.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Endocrinology & Metabolism
Athan G. Dial, Cynthia M. F. Monaco, Grace K. Grafham, Tirth P. Patel, Mark A. Tarnopolsky, Thomas J. Hawke
Summary: The study revealed that the decline in maximal muscle contraction was faster in individuals with type 1 diabetes after the age of 35, accompanied by morphological changes associated with accelerated aging. Additionally, there were differences in muscle fiber composition, including levels of fiber grouping and hybrid fibers, between genders in diabetes patients.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Chemistry, Multidisciplinary
Kim Sarah Koeck, Sahar Salehi, Martin Humenik, Thomas Scheibel
Summary: This study focuses on achieving good mechanical stability of collagen fibers through self-assembly during wet-spinning without the need for additional crosslinkers. The produced collagen fibers show fibril alignment and a unique D-band pattern, and are processed into hierarchical assemblies using textile-engineering techniques. These assemblies serve as excellent substrates for muscle microtissue formation, particularly at the muscle-tendon-junction (MTJ) where myoblasts and fibroblasts are co-cultured to develop an MTJ-model.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Food Science & Technology
Peiyuan Li, Ruilin Xu, Yanfei Shi, Xiaoyang Shi, Xinyuan Zhang, Jinjie Li, Guangning Kou
Summary: This study found that luteolin can increase the proportion of slow myofibers and improve skeletal muscle fitness by activating the FLCN-AMPK-PGC-1α pathway.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Article
Biochemistry & Molecular Biology
Siti Liyana Saud Gany, Jen Kit Tan, Kok Yong Chin, Nur Haleeda Hakimi, Nazirah Ab Rani, Nurhazirah Ihsan, Suzana Makpol
Summary: Ageing leads to a gradual decrease in muscle mass and function, but tocotrienol-rich fraction (TRF) supplementation can protect against age-associated chronic diseases and metabolic disorders. This study found that TRF treatment improved muscle metabolomes and metabolic pathways in ageing rats, promoting amino acid synthesis and muscle regeneration.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Food Science & Technology
Jinjie Li, Yi Li, Xiangying Suo, Jiangtao Li, Da Huang, Guangning Kou
Summary: Bayberry extract has been found to enhance grip strength and metabolic rate in mice, as well as increase the size and percentage of fast-twitch muscle fibers while decreasing slow-twitch fibers. This effect is likely due to its activation of the Akt-FoxO1 pathway. These findings suggest that bayberry extract could be a potential therapy for improving glucose homeostasis in skeletal muscle.
Article
Endocrinology & Metabolism
Alexandra Fahrner, Nikoleta Alchus Laiferova, Barbara Ukropcova, Jozef Ukropec, Jan Krutzfeldt
Summary: Type 2 diabetes negatively affects muscle health. Paracrine signaling in the adult muscle stem cells niche is activated in T2D. The PDGF-miR-501 signaling pathway could be used to classify patients in clinical trials aiming to improve muscle health and glucose homeostasis in diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Multidisciplinary Sciences
Atsuki Fukutani, Shiho Kunimatsu, Tadao Isaka
Summary: This study examined the influence of caffeine on cross-bridge dynamics and found that the effect of caffeine on cross-bridge dynamics is negligible. The ergogenic effect of caffeine is primarily achieved through facilitating Ca2+ release.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Orlando Laitano, Gerard P. Robinson, Kevin O. Murray, Christian K. Garcia, Alex J. Mattingly, Deborah Morse, Michelle A. King, John D. Iwaniec, Jamal M. Alzahrani, Thomas L. Clanton
Summary: The study revealed that Myd88 signaling in skeletal muscle plays a significant role in the innate immune inflammatory response to peritoneal sepsis, affecting the regulation of inflammatory cytokines and the cellular composition of the peritoneal fluid.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Kosmas Kosmas, Zoe Michael, Aimilia Eirini Papathanasiou, Fotios Spyropoulos, Elio Adib, Ravi Jasuja, Helen Christou
Summary: Pulmonary arterial hypertension (PAH) is a severe disease that requires improved therapies. A study on an animal model shows that PAH can cause skeletal muscle dysfunction, possibly due to a shift in skeletal muscle fiber-type specification.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Luke K. Fuerniss, Bradley J. Johnson
Summary: This study validated a semi-automated workflow that can efficiently and objectively identify the type and measure the size of muscle fibers compared to a manual technique. The semi-automated workflow is six times faster than the manual workflow and yields similar results. This study demonstrates the efficiency and objectivity of the semi-automated workflow in imaging, classifying, and measuring muscle fibers.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Orthopedics
Karoliny Lisandra Teixeira Cruz, Ana Cristina Resende Camargos, Juliana Cardoso, Cyntia Rogean de Jesus Alves de Baptista, Aline Duprat Ramos, Ana Claudia Mattiello-Sverzut, Joshua Burns, Hercules Ribeiro Leite
Summary: The study successfully translated and cross-culturally adapted the CMTPedS into Brazilian Portuguese and assessed 20 individuals with CMT. The CMTPedS-Br showed good reliability and face validity in assessing children and youth with CMT.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2021)
Article
Rehabilitation
Gabriela Barroso de Queiroz Davoli, Thais Cristina Chaves, Mariane Lopes, Edson Zangiacomi Martinez, Claudia Ferreira da Rosa Sobreira, H. Kerr Graham, Ana Claudia Mattiello-Sverzut
Summary: The study aimed to perform a cross-cultural adaptation of the Functional Mobility Scale to Brazilian Portuguese and analyze its construct validity and intra-rater reliability in caregivers of children and adolescents with spina bifida. The results showed acceptable intra-rater reliability and construct validity of the FMS in measuring the mobility level of SB patients, recommending its use in clinical practice and research.
DISABILITY AND REHABILITATION
(2022)
Article
Neurosciences
Bruna E. B. Hilario, Marcelo Lima de Oliveira, Pamela Maria M. Barbosa, Daniela M. S. Cunha, Gabriela dos Santos Rigobello, Juliano F. Mendes, Denismar A. Nogueira, Denise Hollanda Iunes, Leonardo Cesar Carvalho
Summary: This study found that using different insoles can modify biomechanical variables and increase dynamic stability in recreational runners during running.
Article
Pediatrics
Cyntia Rogean de Jesus Alves de Baptista, Beatriz Garcia, Juliana Cardoso, Adriana Nascimento Elias, Beatriz Parra Buzzetti, Ana Claudia Mattiello-Sverzut
Summary: This study assessed the gait capacity of youths with Charcot Marie Tooth disease (CMT) and used different foot postures as a grouping variable. The results showed that gait performance was decreased in the CMT group compared to the non-CMT group. Contrary to expectations, the cavus foot type did not show lower gait capacity than the flatfoot.
Article
Rehabilitation
Kathylce Jaqueline Vital Vieira, Leonardo Cesar Carvalho, Juliana Bassalobre Carvalho Borges, Carlos Jose dos Reis, Denise Hollanda Iunes
Summary: This study evaluated the respiratory effects of a Pilates method (PM) in adult women and found that it can improve respiratory muscle strength.
JOURNAL OF BODYWORK AND MOVEMENT THERAPIES
(2022)
Article
Pediatrics
Mariana Angelica de Souza, Edson Zangiacomi Martinez, Elisangela Aparecida da Silva Lizzi, Ananda Cezarani, Gabriela Barroso de Queiroz Davoli, Marjory Irineu Bena, Claudia Ferreira da Rosa Sobreira, Ana Claudia Mattiello-Sverzut
Summary: The modified sphygmomanometer appears to be more suitable than the dynamometer for measuring handgrip strength in patients with Duchenne muscular dystrophy (DMD) at all stages.
Article
Integrative & Complementary Medicine
Flavia da Silva Menezes, Erika de Cassia Lopes Chaves, Ana Paula Aparecida Mantuani, Ligia de Sousa Marino, Marcela Albertini Roquim Alcantara, Melissa Santos Nassif, Caroline de Castro Moura, Leonardo Cesar Carvalho, Denise Hollanda Iunes
Summary: This study evaluated the effect of laser auriculotherapy on chronic spinal pain. The results showed that laser auriculotherapy can significantly reduce pain intensity and increase the nociceptive threshold. These effects remained 15 days after the treatment.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2022)
Article
Rehabilitation
Danila Cristina Petian-Alonso, Ani Caroline de Castro, Gabriela Barroso de Queiroz Davoli, Edson Zangiacomi Martinez, Ana Claudia Mattiello-Sverzut
Summary: This study verified that the combination of 10MWT and MFM can classify the ambulation status of DMD patients, providing a basis for therapists to adjust rehabilitation strategies and goals.
DISABILITY AND REHABILITATION
(2023)
Article
Engineering, Biomedical
Emanuela Juvenal Martins, Ana Claudia Mattiello-Sverzut, Camila Scarpino Barboza Franco, Tenysson Will de Lemos, Per Aagaard
Summary: The study showed significant impairments in maximal and rapid elbow muscle force characteristics in youth with spina bifida. These findings are important for evaluating and assisting in the rehabilitation training of individuals with spina bifida.
CLINICAL BIOMECHANICS
(2023)
Article
Rehabilitation
Emanuela J. Martins, Paula Serrao, Marisa M. Leonardi-Figueiredo, Leticia S. Ravanelli, Felipe S. Serenza, Stela Mattiello, Per Aagaard, Ana Mattiello-Sverzut
Summary: This study found that children and adolescents with spina bifida have reduced arm muscle strength compared to their typically developing peers, particularly during propulsive wheelchair activities. Handheld dynamometry and isokinetic dynamometry produce similar results, supporting the use of handheld dynamometry in a clinical setting.
PHYSIOTHERAPY THEORY AND PRACTICE
(2022)
Article
Clinical Neurology
Mariana Angelica De Souza Leon, Daiane Leite Da Roza, Gabriela Barroso De Queiroz Davoli, Cyntia Rogean De Jesus Alves De Baptista, Claudia Ferreira Da Rosa Sobreira, Ana Claudia Mattiello-Sverzut
Summary: This study aimed to describe the clinical manifestations of DMD by developing percentile curves for various measures. The generated curves can help healthcare professionals and caregivers track the progression of the disease in DMD patients.
Article
Health Policy & Services
Ricardo da Silva Alves, Jovana Maria de Carvalho, Juliana Bassalobre Carvalho Borges, Denismar Alves Nogueira, Denise Hollanda Iunes, Leonardo Cesar Carvalho
Summary: This study aimed to analyze the influence of exergaming on quality of life, cancer-related fatigue, electromyography, and muscle strength and endurance in cancer patients undergoing chemotherapy. The results showed that exergaming can improve cancer-related fatigue and quality of life, as well as increase muscle strength and endurance. This has important implications for cancer patients undergoing chemotherapy.
GAMES FOR HEALTH JOURNAL
(2023)
Review
Clinical Neurology
Danila Cristina Petian-Alonso, Camila Scarpino Barboza Franco, Emanuela Juvenal Martins, Karoliny Lisandra Teixeira Cruz, Roberta de Fatima Carreira Moreira Padovez, Ana Claudia Mattiello-Sverzut
Summary: This study aimed to identify the equipment and protocols commonly used to assess upper limb motor fatigability in patients with neuromuscular disease. The findings revealed that isokinetic and handgrip dynamometers were the most frequently used equipment, while the methodological quality of a majority of the studies was low.
ACTA NEUROLOGICA SCANDINAVICA
(2023)
Article
Biology
A. C. Mattiello-Sverzut, E. J. Martins
Summary: This cross-sectional study investigated the morphological adaptations and performance of the biceps brachii muscle and elbow flexors in healthy individuals in the early phase of aging. The results showed that there were no significant differences in fiber diameter between age groups for both sexes. The proportion of oxidative fibers decreased in men and increased in women with age. Peak torque and total work did not change over the analyzed decades of life.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2023)