Article
Nutrition & Dietetics
Karolina Lagowska, Nicole C. A. Strock, Kristen J. Koltun, Nancy I. Williams, Mary Jane De Souza
Summary: This study investigated the relationship between diet quality and hormonal status in women with subclinical menstrual disturbances and found that poor diet quality is related to altered hormonal parameters, which may have implications for future nutritional treatment strategies.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2022)
Article
Endocrinology & Metabolism
Michelle Maher, Aedin O' Keeffe, Niamh Phelan, Lucy Ann Behan, Sonya Collier, David Hevey, Lisa Owens
Summary: The COVID-19 pandemic has had a significant impact on female reproductive health, with increased levels of psychological distress and poor sleep associated with menstrual cycle disruption.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Niamh Phelan, Lucy Ann Behan, Lisa Owens
Summary: The COVID-19 pandemic has significantly impacted women's reproductive health, leading to changes in menstrual cycles, worsening premenstrual symptoms, and the emergence of other discomfort symptoms. Many women experienced weight gain, worsened diet, increased work hours, and negative effects on their emotional and mental health during the pandemic.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Medicine, General & Internal
Elisabeth Reiser, Julia Lanbach, Bettina Boettcher, Bettina Toth
Summary: Menstrual irregularities are common in polycystic ovary syndrome (PCOS), and pharmacological treatment options play a crucial role in restoring menstrual frequency. This systematic literature research aimed to evaluate the effects of non-hormonal pharmacological treatments on menstrual irregularities in adolescents with PCOS. The findings suggest that metformin, Glucagon-like peptide 1 receptor agonists, and supplements can effectively regulate menstrual cycles in adolescents with PCOS. Further studies are needed to assess the therapy in lean and normal-weight girls with PCOS.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Endocrinology & Metabolism
Mirte R. Caanen, Henrike E. Peters, Peter M. van de Ven, Anne M. F. M. Juttner, Joop S. E. Laven, Marcel H. A. van Hooff, Cornelis B. Lambalk
Summary: The study found that higher AMH levels in adolescence were associated with a higher risk of developing PCOS in adulthood for girls with oligomenorrhea. However, adolescent AMH levels alone or in combination with menstrual irregularities were not effective in predicting adult PCOS, and therefore routine use in clinical practice is not recommended.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Kai-Lun Hu, Kwanghann Gan, Yue Ying, Junyan Zheng, Ruixue Chen, Jinglei Xue, Yiqing Wu, Yifeng Liu, Yimin Zhu, Lanfeng Xing, Dan Zhang
Summary: The study found a close association between menstrual cycle length and anti-Mullerian hormone (AMH) levels and ovarian response. In women without polycystic ovary syndrome (PCOS), those with short cycles and oligo/amenorrhea showed different levels of antral follicle count and serum AMH levels. This association differed in women with PCOS.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
Lucia B. Palmero, Victor Martinez-Perez, Miriam Tortajada, Guillermo Campoy, Luis J. Fuentes
Summary: This study assessed the effects of progesterone on vigilance tasks and differentiated between exogenous and endogenous components. The results showed that Morning-type females performed better during the mid-luteal phase, while Evening-type females performed worse.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Alan Penzias, Ricardo Azziz, Kristin Bendikson, Tommaso Falcone, Karl Hansen, Micah Hill, William Hurd, Sangita Jindal, Suleena Kalra, Jennifer Mersereau, Catherine Racowsky, Robert Rebar, Richard Reindollar, Anne Steiner, Cigdem Tanrikut, Dale Stovall, Hugh Taylor, Belinda Yauger, Molly Moravek, Steven Young
Summary: Luteal phase deficiency (LPD) is a clinical diagnosis characterized by an abnormal luteal phase length, with potential causes including inadequate progesterone duration, levels, or resistance. LPD may not necessarily cause infertility or recurrent pregnancy loss, and there is controversy surrounding the diagnosis and treatment proposals.
FERTILITY AND STERILITY
(2021)
Review
Environmental Sciences
Marta Gimunova, Alexandra Paulinyova, Martina Bernacikova, Ana Carolina Paludo
Summary: This study aimed to review the prevalence of menstrual disorders in female athletes from different sports modalities. The results showed that gymnastics and endurance disciplines had a higher prevalence of menstrual disorders, while team sports such as volleyball and soccer also had a considerable percentage of menstrual disorders compared to the general population.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Behavioral Sciences
Jiajia Xie, Yang Lu, Jianhua Li, Weidong Zhang
Summary: This study investigated the neural responses of females to risk stimuli in different menstrual cycle phases using EEG and an economic risk-taking task. The results showed that women in the midluteal phase exhibited a stronger early neural response to high-risk stimuli, indicating a heightened sensitivity to high risk during this phase.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Neurosciences
Fangshu Yao, Kepu Chen, Yiyun Zhuang, Xueer Shen, Xiaochun Wang
Summary: The study found that the menstrual cycle can affect women's olfactory function, with better olfactory discrimination performance observed during the mid-luteal phase. Additionally, better olfactory discrimination and worse olfactory threshold in the mid-luteal phase may predict fewer emotional symptoms and lower behavioral impulsivity, respectively.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Nutrition & Dietetics
Eduard Maury-Sintjago, Alejandra Rodriguez-Fernandez, Julio Parra-Flores, Marcela Ruiz-De la Fuente
Summary: The aim of the study was to determine the association between menstrual cycle phase and resting metabolic rate (RMR) as well as dietary intake. The results showed that lean women had increased RMR, caloric intake, and lipid intake during the luteal phase, while women with obesity only had increased carbohydrate intake.
Review
Endocrinology & Metabolism
Meczekalski Blazej, Niwczyk Olga, Battipaglia Christian, Troia Libera, Kostrzak Anna, Bala Gregory, Maciejewska-Jeske Marzena, Alessandro D. Genazzani, Luisi Stefano
Summary: Functional hypothalamic amenorrhea is a common cause of amenorrhea in women, characterized by chronic anovulation and absence of menstruation due to disruption in hypothalamic gonadotropin-releasing hormone secretion. Impairment of neurotransmitters plays a key role in its development.
Article
Endocrinology & Metabolism
Darwin A. Guevarra, Courtney C. Louis, Lilianne M. Gloe, Stefanie Russman Block, Deborah A. Kashy, Kelly L. Klump, Jason S. Moser
Summary: The study found increased anhedonic depression in the mid-luteal phase of the menstrual cycle for women, but no significant changes in anxious apprehension and anxious arousal. Additionally, there was a positive association between stress and anxious apprehension as well as anhedonic depression, but not anxious arousal. These associations were not stronger in the mid-luteal phase, providing weak evidence for a window of vulnerability for affective symptoms during this phase.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Behavioral Sciences
Malihe Eskandari Torbaghan, Ali Moghimi, Hamid Reza Kobravi, Masoud Fereidoni, Imanollah Bigdeli
Summary: This study aimed to investigate the effect of estradiol on stress and effect of stress on spatial working memory during the menstrual cycle. The results showed that estradiol levels decreased in the late follicular, luteal, and early follicular phases, while galvanic skin response decreased after stress induction in all three phases. Spatial working memory diminished after stress induction in all three phases, but increased in the late follicular phase. Average power spectrum density in all frequency bands increased after stress induction in the frontal and prefrontal channels. Therefore, stress led to spatial working memory dysfunction, while estradiol improved spatial working memory performance in the late follicular phase.
BRAIN AND BEHAVIOR
(2023)
Article
Obstetrics & Gynecology
Daimin Wei, Yuhua Shi, Jing Li, Ze Wang, Lin Zhang, Yun Sun, Hong Zhou, Yuping Xu, Chunxiang Wu, Ling Liu, Qiongfang Wu, Lili Zhuang, Yanzhi Du, Weiping Li, Heping Zhang, Richard S. Legro, Zi-Jiang Chen
HUMAN REPRODUCTION
(2017)
Article
Endocrinology & Metabolism
Richard S. Legro, Allen R. Kunselman, Christy M. Stetter, Carol L. Gnatuk, Stephanie J. Estes, Eleanor Brindle, Hubert W. Vesper, Julianne C. Botelho, Peter A. Lee, William C. Dodson
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Clinical Neurology
C. Flaherty, J. Kraft, A. Brothers, M. Harrison, R. S. Legro, A. Manni, C. Yang, Z. Simmons
AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION
(2017)
Review
Obstetrics & Gynecology
Richard S. Legro
FERTILITY AND STERILITY
(2017)
Article
Medicine, General & Internal
Xiao-Ke Wu, Elisabet Stener-Victorin, Hong-Ying Kuang, Hong-Li Ma, Jing-Shu Gao, Liang-Zhen Xie, Li-Hui Hou, Zhen-Xing Hu, Xiao-Guang Shao, Jun Ge, Jin-Feng Zhang, Hui-Ying Xue, Xiao-Feng Xu, Rui-Ning Liang, Hong-Xia Ma, Hong-Wei Yang, Wei-Li Li, Dong-Mei Huang, Yun Sun, Cui-Fang Hao, Shao-Min Du, Zheng-Wang Yang, Xin Wang, Ying Yan, Xiu-Hua Chen, Ping Fu, Cai-Fei Ding, Ya-Qin Gao, Zhong-Ming Zhou, Chi Chiu Wang, Tai-Xiang Wu, Jian-Ping Liu, Ernest H. Y. Ng, Richard S. Legro, Heping Zhang
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2017)
Letter
Endocrinology & Metabolism
Richard S. Legro, Peter A. Lee
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Endocrinology & Metabolism
Lidija K. Gorsic, Gulum Kosova, Brian Werstein, Ryan Sisk, Richard S. Legro, M. Geoffrey Hayes, Jose M. Teixeira, Andrea Dunaif, Margrit Urbanek
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2017)
Article
Endocrinology & Metabolism
Nazia Raja-Khan, Katrina Agito, Julie Shah, Christy M. Stetter, Theresa S. Gustafson, Holly Socolow, Allen R. Kunselman, Diane K. Reibel, Richard S. Legro
Review
Medicine, General & Internal
Rui Wang, Bobae V. Kim, Madelon van Wely, Neil P. Johnson, Michael F. Costello, Hanwang Zhang, Ernest Hung Yu Ng, Richard S. Legro, Siladitya Bhattacharya, Robert J. Norman, Ben Willem J. Mol
BMJ-BRITISH MEDICAL JOURNAL
(2017)
Review
Medicine, General & Internal
Rui Wang, Bobae V. Kim, Madelon van Wely, Neil P. Johnson, Michael F. Costello, Hanwang Zhang, Ernest Hung Yu Ng, Richard S. Legro, Siladitya Bhattacharya, Robert J. Norman, Ben Willem J. Mol
BMJ-BRITISH MEDICAL JOURNAL
(2017)
Article
Endocrinology & Metabolism
Molly M. Quinn, Chia-Ning Kao, Asima K. Ahmad, Daniel J. Haisenleder, Nanette Santoro, Esther Eisenberg, Richard S. Legro, Marcelle I. Cedars, Heather G. Huddleston
CLINICAL ENDOCRINOLOGY
(2017)
Article
Obstetrics & Gynecology
Michael P. Diamond, Richard S. Legro, Christos Coutifaris, Ruben Alvero, Randal D. Robinson, Peter A. Casson, Gregory M. Christman, Hao Huang, Karl R. Hansen, Valerie Baker, Rebecca Usadi, Aimee Seungdamrong, G. Wright Bates, R. Mitchell Rosen, William Schlaff, Daniel Haisenleder, Stephen A. Krawetz, Kurt Barnhart, J. C. Trussell, Nanette Santoro, Esther Eisenberg, Heping Zhang
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2017)
Article
Endocrinology & Metabolism
Anuja Dokras, Martin Playford, Penny M. Kris-Etherton, Allen R. Kunselman, Christy M. Stetter, Nancy I. Williams, Carol L. Gnatuk, Stephanie J. Estes, David B. Sarwer, Kelly C. Allison, Christos Coutifaris, Nehal Mehta, Richard S. Legro
CLINICAL ENDOCRINOLOGY
(2017)
Article
Obstetrics & Gynecology
Lawrence Engmann, Susan Jin, Fangbai Sun, Richard S. Legro, Alex J. Polotsky, Karl R. Hansen, Christos Coutifaris, Michael P. Diamond, Esther Eisenberg, Heping Zhang, Nanette Santoro
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2017)
Article
Obstetrics & Gynecology
Aaron K. Styer, Susan Jin, Dan Liu, Baisong Wang, Alex J. Polotsky, Mindy S. Christianson, Wendy Vitek, Lawrence Engmann, Karl Hansen, Robert Wild, Richard S. Legro, Christos Coutifaris, Ruben Alvero, Randal D. Robinson, Peter Casson, Gregory M. Christman, Alicia Christy, Michael P. Diamond, Esther Eisenberg, Heping Zhang, Nanette Santoro
FERTILITY AND STERILITY
(2017)