Article
Endocrinology & Metabolism
An-ran Ma, Fang Liu, Runnan Wang, Lanmei Lin, Yilun Wang, Qunyi Li, Xiaonian Lu, Juan Du
Summary: This study found a higher prevalence of MetS and its components in patients with EP, with factors such as MetS, abdominal obesity, hypertension, smoking, and alcohol use being positive independent predictors of EP. Early intervention for correcting these cardiovascular risk factors is encouraged for managing EP.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Michal Fishel Bartal, George Saade, Alan T. Tita, Baha M. Sibai
Summary: The publication of the Chronic Hypertension and Pregnancy (CHAP) trial has already changed the way mild chronic hypertension in pregnant people is managed. However, it has also led to confusion regarding the implementation and management of the trial findings. This article addresses aspects of implementation and discusses clinical questions that may impact the management of patients with chronic hypertension following the trial.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Review
Endocrinology & Metabolism
Florian G. Scurt, Maximilian J. Ganz, Carolin Herzog, Katrin Bose, Peter R. Mertens, Christos Chatzikyrkou
Summary: The prevalence of kidney disease is increasing rapidly worldwide due to rising rates of obesity, diabetes, and metabolic syndrome. These conditions place a significant financial burden on healthcare systems. Despite treatment options, there is still a significant risk of progression to end-stage renal disease in high-risk obese and diabetic populations. The metabolic syndrome adversely affects the development and progression of chronic kidney failure. Understanding the underlying mechanisms of metabolic syndrome-associated kidney disease is important in developing strategies for prevention and slowing disease progression.
Article
Dermatology
Meron Teklu, Wunan Zhou, Promita Kapoor, Nidhi Patel, Amit K. Dey, Alexander V. Sorokin, Grigory A. Manyak, Heather L. Teague, Julie A. Erb-Alvarez, Aparna Sajja, Khaled M. Abdelrahman, Aarthi S. Reddy, Domingo E. Uceda, Sundus S. Lateef, Sujata M. Shanbhag, Colin Scott, Nina Prakash, Maryia Svirydava, Philip Parel, Justin A. Rodante, Andrew Keel, Evan L. Siegel, Marcus Y. Chen, David A. Bluemke, Martin P. Playford, Joel M. Gelfand, Nehal N. Mehta
Summary: The study revealed a significant association between metabolic syndrome and its factors with noncalcified coronary burden in patients with psoriasis. Individuals with metabolic syndrome had higher cardiovascular disease risk factors and systemic inflammation, highlighting the importance of increasing awareness and addressing metabolic syndrome in psoriasis patients to reduce cardiovascular risk.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2021)
Review
Immunology
Yan Hao, Ya-juan Zhu, Song Zou, Pei Zhou, Ya-wen Hu, Qi-xiang Zhao, Lin-na Gu, Hao-zhou Zhang, Zhen Wang, Jiong Li
Summary: The association between psoriasis and metabolic syndrome involves various mechanisms including endoplasmic reticulum stress, pro-inflammatory cytokine releases, excess production of reactive oxygen species, alterations in adipocytokine levels, and gut microbiota dysbiosis.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Endocrinology & Metabolism
Ahmad Khalid Aalemi, Mohammad Barin Bahain, Abdul Ghafar Hamdard
Summary: The study confirmed the association between psoriasis and metabolic syndrome, highlighting the importance of screening psoriatic patients for metabolic syndrome.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2021)
Article
Medicine, General & Internal
Seyedeh Melika Fanaei, Ladan Mehran, Atieh Amouzegar, Safdar Masoumi, Atefeh Amouzegar, Freidoun Azizi
Summary: This study found a significant association between metabolic syndrome and the development of chronic kidney disease after 18 years of follow-up. Hypertension, diabetes, and age were strong indicators of chronic kidney disease incidence, while abdominal obesity and low-density lipoprotein were not associated with the incidence of chronic kidney disease.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Endocrinology & Metabolism
Monika Drozdz, Anna Moczulska, Andrzej Rudzinski, Dorota Drozdz
Summary: This study aimed to identify the most significant risk factors of left ventricular hypertrophy (LVH) in children with chronic kidney disease (CKD). The results showed that metabolic syndrome, hypertension, and CKD stage were the most important risk factors for LVH.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Tangui Barre, Helene Fontaine, Stanislas Pol, Clemence Ramier, Vincent Di Beo, Camelia Protopopescu, Fabienne Marcellin, Morgane Bureau, Marc Bourliere, Celine Dorival, Ventzislava Petrov-Sanchez, Tarik Asselah, Elisabeth Delarocque-Astagneau, Dominique Larrey, Jean-Charles Duclos-Vallee, Fabrice Carrat, Patrizia Carrieri
Summary: A study on HBV-infected individuals found that consuming >= 3 cups of coffee per day was associated with a higher risk of dyslipidemia and a lower risk of hypertension. There was no significant association with diabetes. Further research is needed to determine whether these metabolic benefits translate into reduced mortality risk for patients.
Review
Medicine, Research & Experimental
Daciana Elena Branisteanu, Ruxandra Angela Pirvulescu, Alina Elena Spinu, Elena Andrese Porumb, Mihaela Cojocaru, Alin Codrut Nicolescu, Daniel Constantin Branisteanu, Catalina Ioana Branisteanu, Andreea Dimitriu, Anisia Iuliana Alexa, Mihaela Paula Toader
Summary: Psoriasis is a chronic inflammatory and immune-mediated condition that may affect the entire body, not just the skin. Patients with psoriasis are more likely to have comorbidities such as obesity and diabetes, and early recognition of these comorbidities is crucial for timely treatment. Dermatologists, who are often the first medical contact for psoriasis patients, play an important role in informing patients about the association between psoriasis and comorbidities, and devising prevention and treatment plans.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2022)
Review
Endocrinology & Metabolism
Ming Yang, Chongbin Liu, Na Jiang, Yan Liu, Shilu Luo, Chenrui Li, Hao Zhao, Yachun Han, Wei Chen, Li Li, Li Xiao, Lin Sun
Summary: Metabolic syndrome is a complex metabolic disorder characterized by obesity, insulin resistance/diabetes, hyperlipidemia, and hypertension. The increasing incidence of metabolic syndrome poses a heavy medical burden, yet effective prevention and treatment strategies are still lacking. Fibroblast growth factor 21 (FGF21) is a key protein involved in maintaining metabolic homeostasis and has potential as a target for the treatment of metabolic syndrome by reducing fat mass and improving glucose and lipid metabolism.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Chemistry, Medicinal
Azar Hosseini, Bibi Marjan Razavi, Maciej Banach, Hossein Hosseinzadeh
Summary: Quercetin, as an important flavonoid, has potential effects in improving symptoms of metabolic syndrome, but further research and clinical trials are needed to determine its true clinical value.
PHYTOTHERAPY RESEARCH
(2021)
Review
Nutrition & Dietetics
Nur Hanisah Mohamed Haris, Shanthi Krishnasamy, Kok-Yong Chin, Vanitha Mariappan, Mohan Arumugam
Summary: This review aimed to identify and summarize the screening criteria for metabolic syndrome and the methods used in nutrition assessment among patients with plaque psoriasis. The study found that patients with psoriasis had a high prevalence of metabolic syndrome and poor nutritional status, with deficiencies in vitamin D. However, only anthropometric measures were employed to assess the nutritional status, highlighting the need for additional assessments and suitable interventions.
Article
Endocrinology & Metabolism
Ying Liu, Ping Shuai, Wanjing Chen, Yuping Liu, Dongyu Li
Summary: This study investigates the association between Helicobacter pylori (H. pylori) infection and metabolic syndrome (MetS) using five different criteria to define MetS. The results show that in males, the prevalence of MetS is higher in the H. pylori-positive group compared to the negative group, while in females, similar results are observed using three international criteria. Multivariate logistic regression analysis reveals a positive correlation between H. pylori infection and MetS in males. Additionally, H. pylori infection is found to be positively correlated with waist circumference in the general population, and with hypertension and hyperglycemia in males.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Medicine, General & Internal
Ju Qiao, Qian-Nan Jia, Hong-Zhong Jin
Summary: The study found an association between psoriasis and metabolic syndrome, and treating metabolic syndrome in patients with psoriasis may improve psoriasis and reduce the risk of cardiovascular disease.
ARCHIVES OF MEDICAL SCIENCE
(2021)
