The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice

Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation

(2014) A. Contreras-Ferrat et al.   JOURNAL OF CELL SCIENCE

Cholesterol Accumulation in Podocytes: A Potential Novel Targetable Pathway in Diabetic Nephropathy

(2013) A. Tufro   DIABETES

Cyclodextrin Protects Podocytes in Diabetic Kidney Disease

(2013) S. Merscher-Gomez et al.   DIABETES

Doc2b promotes GLUT4 exocytosis by activating the SNARE-mediated fusion reaction in a calcium- and membrane bending–dependent manner

(2013) Haijia Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3K -Akt-AS160 in Skeletal Muscle Cells

(2012) C. Osorio-Fuentealba et al.   DIABETES

AMPK Enhances Insulin-Stimulated GLUT4 Regulation via Lowering Membrane Cholesterol

(2012) Kirk M. Habegger et al.   ENDOCRINOLOGY

Effect of Plasma Membrane Cholesterol Depletion on Glucose Transport Regulation in Leukemia Cells

(2012) Cristiana Caliceti et al.   PLoS One

Endocytosis, Recycling, and Regulated Exocytosis of Glucose Transporter 4

(2011) Kevin Foley et al.   BIOCHEMISTRY

C2 Domain-Containing Phosphoprotein CDP138 Regulates GLUT4 Insertion into the Plasma Membrane

(2011) Xiangyang Xie et al.   Cell Metabolism

Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle

(2011) K. M. Habegger et al.   DIABETOLOGIA

Evidence Coupling Increased Hexosamine Biosynthesis Pathway Activity to Membrane Cholesterol Toxicity and Cortical Filamentous Actin Derangement Contributing to Cellular Insulin Resistance†

(2011) Padma Bhonagiri et al.   ENDOCRINOLOGY

Shikonin Increases Glucose Uptake in Skeletal Muscle Cells and Improves Plasma Glucose Levels in Diabetic Goto-Kakizaki Rats

(2011) Anette I. Öberg et al.   PLoS One

Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis

(2011) Nolan J. Hoffman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Muscle insulin resistance: assault by lipids, cytokines and local macrophages

(2010) Girish Kewalramani et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers

(2010) Mariana Casas et al.   JOURNAL OF GENERAL PHYSIOLOGY

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells

(2009) Johanna T. Lanner et al.   FASEB JOURNAL

Targeting of PKCζ and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

(2008) Eric Hajduch et al.   BIOCHEMICAL JOURNAL

Ca2+ and insulin-mediated glucose uptake

(2008) J LANNER et al.   CURRENT OPINION IN PHARMACOLOGY

Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

(2008) Charlotte J. Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Skeletal L-type Ca2+Current Is a Major Contributor to Excitation-coupled Ca2+entry

(2008) Roger A. Bannister et al.   JOURNAL OF GENERAL PHYSIOLOGY

Cyclodextrins

(2008) Valentino J. Stella et al.   TOXICOLOGIC PATHOLOGY

The GLUT4 Code

(2007) Mark Larance et al.   MOLECULAR ENDOCRINOLOGY