Article
Materials Science, Ceramics
Mostafizur Rahman, Mohammad Asaduzzaman Chowdhury, Md Shahin Mia, Md Ramjan Ali, Atiqur Rahman, Md Osman Ali, Saifullah Mahmud
Summary: This study reported a novel interfacial engineering approach for the fabrication of polymer/ceramic hybrid coating on magnesium alloy, which significantly improved mechanical properties, enhanced biointerface property, and slowed down degradation in simulated body fluid. The hybrid coating also improved corrosion resistance and enhanced biocompatibility and bioactivity.
CERAMICS INTERNATIONAL
(2022)
Article
Chemistry, Applied
Hui Shi, Liu Hong, Kai Pan, Wei Wei, Xiaoya Liu, Xiaojie Li
Summary: The study introduces a biodegradable polyacrylate copolymer coating to enhance the corrosion resistance and biocompatibility of magnesium alloys. The coating significantly reduces the corrosion rate and improves the cytocompatibility of the alloy.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Materials Science, Multidisciplinary
Haoran Zheng, Zhen Li, Minfang Chen, Chen You, Jingbo Wang
Summary: The in vitro and in vivo performance of NaMgF3 coating on Mg-3Zn-0.2Ca (MZC) alloy for bone applications was investigated. The NaMgF3 coating effectively reduced the corrosion rate of MZC alloy, enhanced its mechanical support and biocompatibility in bone repair applications.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Chemistry, Physical
Jun Li, Timothy A. Hacker, Hao Wei, Yin Long, Fan Yang, Dalong Ni, Allison Rodgers, Weibo Cai, Xudong Wang
Summary: The study showed that the implantable nanogenerator system was biocompatible and safe for long-term operation, with no adverse effects on heart function over a 2-month testing period. Implanting i-NGs may be a feasible way to power the next generation of CIEDs.
Article
Engineering, Biomedical
Sanghun Lee, Sehyeon Park, Junggeon Park, Jae Young Lee
Summary: We developed implantable bioelectrodes with high performance and high biocompatibility by actively modulating the inflammatory response of macrophages. The immobilization of anti-inflammatory cytokine IL-4 on the electrodes successfully induced anti-inflammatory polarization of macrophages, both in vitro and in vivo. These IL-4-immobilized bioelectrodes not only mitigated scarring around the implanted electrodes but also maintained high sensitivity electrocardiogram signals for up to 15 days post-implantation.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Applied
Jie Chen, Xuhui Liu, Qingxiang Hong, Lingjie Meng, Yan Ji, Lingtao Wang, Qiuyang Zhang, Jiafeng Lin, Changjiang Pan
Summary: By modifying the surface of magnesium-based alloys with a novel polymer coating that releases nitric oxide (NO), this study successfully improved the anticorrosion performance, hydrophilicity, and biocompatibility of the magnesium alloy coating, promoting the growth of endothelial cells and enhancing hemocompatibility. This research opens up a new avenue for the development of multifunctional coatings for magnesium-based alloys that can release NO, simultaneously reducing corrosion, improving hemocompatibility, and accelerating endothelial regeneration.
PROGRESS IN ORGANIC COATINGS
(2024)
Article
Materials Science, Coatings & Films
Julia Nachtsheim, Songyun Ma, Jaka Burja, Barbara Setina Batic, Bernd Markert
Summary: This research studied the effect of PEO coating on the long-term corrosion behavior of medical-grade magnesium alloy. The results showed that the PEO coating can significantly control the corrosion of the magnesium alloy and provide valuable information.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Engineering, Biomedical
Xiaoxi Shao, Xiang Wang, Fangfang Xu, Taiqiang Dai, Jack G. Zhou, Jiang Liu, Kun Song, Lei Tian, Bin Liu, Yanpu Liu
Summary: This study investigated the degradation and biocompatibility of a biodegradable Zn-Mg-Fe alloy in vivo. The results showed that the alloy exhibited good biocompatibility and a uniform degradation rate. Zinc accumulated in adjacent bone tissue but not in other organs. The degradation products included zinc oxide, zinc hydroxide, hydrozincite, and hopeite.
BIOACTIVE MATERIALS
(2022)
Article
Engineering, Biomedical
Malgorzata Sikora-Jasinska, Lea M. Morath, Maria P. Kwesiga, Margaret E. Plank, Alexia L. Nelson, Alexander A. Oliver, Martin L. Bocks, Roger J. Guillory, Jeremy Goldman
Summary: The study evaluated the mechanical performance and biodegradation properties of metallic molybdenum (Mo) as a potential material for biodegradable stents. The results showed favorable mechanical behavior and uniform degradation profile, suggesting Mo as an ideal source material for clinical applications. Mo implants in mouse arteries avoided cellular response and showed minimal neointimal hyperplasia, indicating good biocompatibility. However, potential pathological remodeling and impaired kidney function were observed, suggesting further investigation is needed.
BIOACTIVE MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Xiaohui Nan, Wenjia Lai, Dan Li, Jiesheng Tian, Zhiyuan Hu, Qiaojun Fang
Summary: BM, derived from magnetotactic bacteria, have unique advantages for potential use as MRI contrast agents due to their high biocompatibility and specific accumulation in liver and spleen. Long-term in-vivo assessment revealed major elimination pathways and clearance time of BM from mice, supporting their clinical potential as MRI contrast agents.
Article
Engineering, Biomedical
Hui Guo, Jili Hu, Zhenquan Shen, Dexiao Du, Yufeng Zheng, Jirun Peng
Summary: The study systematically investigated the in vivo biodegradation and biocompatibility of gastrointestinal staples made from Zn-0.8 wt.% Li-0.1 wt.% Mn alloy, showing promising results in pig models with good stability and healing capabilities, no significant side effects were observed.
ACTA BIOMATERIALIA
(2021)
Article
Engineering, Chemical
Nicole G. Sommer, Sandra Gieringer, Uwe Y. Schwarze, Annelie-M Weinberg, Talal Al-Samman, Yuri Estrin
Summary: The biodegradation behavior of a ternary alloy Mg-4Li-1Ca (LX41) was investigated in this study. The results showed that although LX41 had a higher biodegradation rate, its implants were well integrated and the faster degradation did not negatively affect bone ingrowth and morphology. The moderate degradation rates observed in the study suggest that long-term outcomes of LX41 implantation will not be detrimental.
Article
Materials Science, Biomaterials
Sourav Dutta, Rabiul Khan, N. Surya Prakash, Sanjay Gupta, Debaki Ghosh, Samit K. Nandi, Mangal Roy
Summary: Magnesium-based composites, reinforced with bioactive SrO-doped magnesium phosphate (MgP), show promising potential as degradable metallic implants. The MgP reinforcement improves the mechanical properties of the composite, while the controlled release of Sr-containing bioactive reinforcement enhances cytotoxicity and osteogenesis. In vivo evaluation using a rabbit femur defect model supports the structural integrity and osteogenic potential of the Mg-MgP composite.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Engineering, Biomedical
Andrea Torroni, Lukasz Witek, Hayat Pelin Fahliogullari, Joao Paulo Bortoli, Amel Ibrahim, Jacques Hacquebord, Nikhil Gupta, Paulo Coelho
Summary: The study found that WE43 Mg alloy exhibited higher degradation rate and bone remodeling in sheep, indicating its suitability for production of resorbable implants, while WE43-T5 showed bone/implant interaction properties that make it more suitable for fabrication of endosteal bone screws. In vitro assays were conducted to investigate possible mechanisms underlying the behavior expressed from the alloysin vivoin vivo.
JOURNAL OF BIOMATERIALS APPLICATIONS
(2021)
Article
Biophysics
S. Thanka Rajan, Mitun Das, A. Arockiarajan
Summary: The study demonstrates that the development of niobium and niobium oxide thin films on Mg alloys using sputtering technique can improve the corrosion resistance and biocompatibility of the alloys. The thin-film coated Mg alloys exhibited good corrosion resistance and cell proliferation capability.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Veterinary Sciences
M. C. Nolff, A. Layer, A. Meyer-Lindenberg
AUSTRALIAN VETERINARY JOURNAL
(2015)
Article
Endocrinology & Metabolism
Paul Schumann, Daniel Lindhorst, Andreas Kampmann, Nils-Claudius Gellrich, Sonja Krone-Wolf, Andrea Meyer-Lindenberg, Constantin von See, Thomas Gander, Martin Lanzer, Martin Rucker, Harald Essig
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2015)
Article
Veterinary Sciences
Mirja C. Nolff, Andrea Meyer-Lindenberg
JOURNAL OF FELINE MEDICINE AND SURGERY
(2015)
Article
Veterinary Sciences
B. Ullmann, N. Seehaus, S. Hungerbuehler, A. Meyer-Lindenberg
JOURNAL OF SMALL ANIMAL PRACTICE
(2016)
Article
Multidisciplinary Sciences
Stefanie M. F. Seiler, Christine Baumgartner, Johannes Hirschberger, Ambros J. Beer, Andreas Bruhschwein, Nina Kreutzmann, Silja Laberke, Melanie C. Wergin, Andrea Meyer-Lindenberg, Johanna Brandl, Anne-Kathrin von Thaden, Eliane Farrell, Markus Schwaiger
Article
Veterinary Sciences
M. C. Nolff, K. M. Flatz, A. Meyer-Lindenberg
SCHWEIZER ARCHIV FUR TIERHEILKUNDE
(2015)
Article
Veterinary Sciences
B. Berger, J. Knebel, S. Steigmeier-Raith, S. Reese, A. Meyer-Lindenberg
TIERAERZTLICHE PRAXIS AUSGABE KLEINTIERE HEIMTIERE
(2015)
Article
Veterinary Sciences
Mirja Christine Nolff, Michael Fehr, Sven Reese, Andrea E. Meyer-Lindenberg
JOURNAL OF FELINE MEDICINE AND SURGERY
(2017)
Article
Veterinary Sciences
M. C. Nolff, S. Reese, M. Fehr, R. Dening, A. Meyer-Lindenberg
JOURNAL OF SMALL ANIMAL PRACTICE
(2016)
Article
Veterinary Sciences
M. C. Nolff, A. Meyer-Lindenberg
TIERAERZTLICHE PRAXIS AUSGABE KLEINTIERE HEIMTIERE
(2016)
Article
Engineering, Biomedical
Ann-Kathrin Gartzke, Stefan Julmi, Christian Klose, Silke Besdo, Anja-Christina Waselau, Andrea Meyer-Lindenberg, Hans Juergen Maier, Peter Wriggers
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2020)
Article
Anatomy & Morphology
Klara Theresia Besuden, Andrea Meyer-Lindenberg, Andreas Bruehschwein
Summary: This study utilized helical CT images to describe the normal anatomy of canine hindlimb veins, retrospectively reviewing 30 dogs that underwent CT venography with a 64-slice helical CT scanner and generating three-dimensional images.
ANATOMIA HISTOLOGIA EMBRYOLOGIA
(2022)
Article
Agriculture, Dairy & Animal Science
Florian Boehmer, Katharina Erber, Anja Ewringmann, Ruth Klein, Sven Reese, Christine Boehmer, Andrea Meyer-Lindenberg, Beate Walter
Summary: This study aimed to investigate the value of serum AMH concentrations in distinguishing spayed from intact female rabbits and its relationship with pseudopregnancy and ovarian follicle numbers. The results showed that a single determination of serum AMH concentrations was adequate to differentiate spayed from intact female rabbits, and the follicular or luteal phase did not significantly influence the measured serum AMH concentrations.
REPRODUCTION IN DOMESTIC ANIMALS
(2022)
Article
Materials Science, Multidisciplinary
N. Kleer, S. Julmi, A. -K. Gartzke, J. Augustin, F. Feichtner, A. -C. Waselau, C. Klose, H. J. Maier, P. Wriggers, A. Meyer-Lindenberg
Article
Veterinary Sciences
Bjoern Berger, Andreas Bruehschwein, Lina Eddicks, Andrea Meyer-Lindenberg
CANADIAN VETERINARY JOURNAL-REVUE VETERINAIRE CANADIENNE
(2016)