Prion protein oligomer and its neurotoxicity

Development of the Structural Core and of Conformational Heterogeneity during the Conversion of Oligomers of the Mouse Prion Protein to Worm-like Amyloid Fibrils

(2012) Jogender Singh et al.   JOURNAL OF MOLECULAR BIOLOGY

Naturally prion resistant mammals

(2012) Natalia Fernández-Borges et al.   Prion

Rabbits are not resistant to prion infection

(2012) F. Chianini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of the X-loop turn of the prion protein linked to scrapie resistance

(2012) A. D. Scouras et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Atomic View of a Toxic Amyloid Small Oligomer

(2012) Arthur Laganowsky et al.   SCIENCE

Defining the Pathway of Worm-like Amyloid Fibril Formation by the Mouse Prion Protein by Delineation of the Productive and Unproductive Oligomerization Reactions

(2011) Shweta Jain et al.   BIOCHEMISTRY

Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death

(2011) W. Kudo et al.   HUMAN MOLECULAR GENETICS

Prion protein polymerisation triggered by manganese-generated prion protein seeds

(2011) Shirley Hesketh et al.   JOURNAL OF NEUROCHEMISTRY

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

(2011) Malin K. Sandberg et al.   NATURE

The α-Helical C-Terminal Domain of Full-Length Recombinant PrP Converts to an In-Register Parallel β-Sheet Structure in PrP Fibrils: Evidence from Solid State Nuclear Magnetic Resonance

(2010) Robert Tycko et al.   BIOCHEMISTRY

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

(2010) Iryna Benilova et al.   EMBO Molecular Medicine

Prion protein and Aβ-related synaptic toxicity impairment

(2010) Anna Maria Calella et al.   EMBO Molecular Medicine

Amyloid oligomers: diffuse oligomer-based transmission of yeast prions

(2010) Hideki Taguchi et al.   FEBS Journal

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states

(2010) Mikael Lindgren et al.   FEBS Journal

Unique Structural Characteristics of the Rabbit Prion Protein

(2010) Yi Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Cross Talk between Misfolded Proteins in Animal Models of Alzheimer's and Prion Diseases

(2010) R. Morales et al.   JOURNAL OF NEUROSCIENCE

Studies on the structural stability of rabbit prion probed by molecular dynamics simulations of its wild-type and mutants

(2010) Jiapu Zhang   JOURNAL OF THEORETICAL BIOLOGY

Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion

(2010) Jerson L. Silva et al.   METHODS

The prion protein as a receptor for amyloid-β

(2010) Helmut W. Kessels et al.   NATURE

Solution Structure and Dynamics of the I214V Mutant of the Rabbit Prion Protein

(2010) Yi Wen et al.   PLoS One

Synthetic amyloid-  oligomers impair long-term memory independently of cellular prion protein

(2010) C. Balducci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion hypothesis: the end of the controversy?

(2010) Claudio Soto   TRENDS IN BIOCHEMICAL SCIENCES

Cross Currents in Protein Misfolding Disorders: Interactions and Therapy

(2009) Rodrigo Morales et al.   CNS & Neurological Disorders-Drug Targets

β-amyloid oligomers and cellular prion protein in Alzheimer’s disease

(2009) Erik C. Gunther et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Core Structure of Amyloid Fibrils Formed by Residues 106–126 of the Human Prion Protein

(2009) Patrick Walsh et al.   STRUCTURE

Molecular Mechanisms of Prion Pathogenesis

(2008) Adriano Aguzzi et al.   Annual Review of Pathology-Mechanisms of Disease

Steric Zipper of the Amyloid Fibrils Formed by Residues 109–122 of the Syrian Hamster Prion Protein

(2008) Shin-Wen Lee et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanisms of prion protein assembly into amyloid

(2008) J. Stohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA