Article
Chemistry, Multidisciplinary
Ediz Kaan Herkert, Domenica Romina Bermeo Alvaro, Martina Recchia, Wolfgang Langbein, Paola Borri, Maria F. Garcia-Parajo
Summary: Biosensing applications often require single-molecule sensitivity in the presence of strong background signals. Plasmonic nanoantennas can confine and enhance light in volumes far below the diffraction limit, making them suitable for these tasks. Hybrid AiB platforms made of both gold and aluminum promise superior performance by providing better background screening and additional enhancements.
Article
Chemistry, Analytical
Mariacristina Turino, Ramon A. Alvarez-Puebla, Luca Guerrini
Summary: This study presents a novel surface-enhanced Raman scattering (SERS) spectroscopy platform for the dynamic sensing of biothiols. By using colloidally stable silver nanoparticles clusters equipped with a specifically designed azobenzene derivative, significant spectral changes can be observed in the presence of small biothiols, which can be quantitatively correlated with the biothiol content.
Article
Chemistry, Multidisciplinary
Kosti Tapio, Amr Mostafa, Yuya Kanehira, Antonio Suma, Anushree Dutta, Ilko Bald
Summary: DNA origami technology enables precise assembly of chemical entities at the nanoscale, creating sophisticated functional materials. By assembling Au or Ag nanoparticle dimers, a versatile DNA origami nanofork antenna (DONA) has been developed, achieving signal enhancements in surface-enhanced Raman scattering (SERS) up to 10(11). Using the DNA origami structure, single-molecule SERS measurements of three dyes, cytochrome c, and horseradish peroxidase proteins have been successfully demonstrated.
Article
Nanoscience & Nanotechnology
Bryson Krause, Minh T. Pham, Hoang M. Luong, Tho D. Nguyen, Thang B. Hoang
Summary: Nanohole arrays can enhance the lasing emission of organic dye liquid gain medium and accelerate the decay rate of CdSe quantum dots. They are simple to fabricate, exhibit excellent optical responses, and have great potential in various emerging technologies such as gas sensing, biomedical imaging, and ultrafast on-chip coherent light sources.
ACS APPLIED NANO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Bryson Krause, Minh T. Pham, Hoang M. Luong, Tho D. Nguyen, Thang B. Hoang
Summary: Periodic arrays of air nanoholes in thin metal films can enhance light-matter interactions at the nanoscale. A simple technique of fabricating hexagonal nanohole arrays is employed, which offers excellent optical responses and can be used for enhanced lasing and spontaneous emission of novel nanomaterials.
ACS APPLIED NANO MATERIALS
(2022)
Article
Physics, Multidisciplinary
Shinki, Shreya Jain, Subhendu Sarkarb
Summary: This study systematically explores the role of thickness of metallic plasmonic layer in controlling SERS behavior. It is found that a 50nm-thick film on a surface with dense and small pyramids has a significantly high SERS contribution.
EUROPEAN PHYSICAL JOURNAL-SPECIAL TOPICS
(2022)
Article
Chemistry, Multidisciplinary
Kevin M. Roccapriore, Shin-Hum Cho, Andrew R. Lupini, Delia J. Milliron, Sergei Kalinin
Summary: The spatial confinement of matter in functional nanostructures has positioned them at the forefront of nanoscience, serving as playgrounds for exotic physics and quantum phenomena as well as finding applications in various fields. Through modern synthesis processes and precise sculpting, the plasmonic response of nanoparticles can be effectively modified, offering a wide range of possibilities for nanophotonic design.
Article
Chemistry, Multidisciplinary
Abhijit Das, Nitin Gupta, Ajay Kumar Agrawal, Anuj Dhawan
Summary: This paper presents a method for fabricating plasmonic nanostructures over a large area for use as SERS substrates, with batch processes that can produce large numbers of substrates in a single run. The effects of different process parameters were studied to optimize sensitivity for molecule detection as low as 100 nM. The fabricated SERS substrates were also evaluated for uniformity and reproducibility, and successfully applied for label-free detection of organophosphorous pesticides.
Review
Spectroscopy
Vanessa Cupil-Garcia, Pietro Strobbia, Bridget M. Crawford, Hsin-Neng Wang, Hoan Ngo, Yang Liu, Tuan Vo-Dinh
Summary: This work provides an overview of the development and application of surface-enhanced Raman scattering (SERS) and plasmonic nanoplatforms, including various sensing platforms for monitoring genomic biomarkers, infectious diseases diagnostics, and cancer biomarker detection. It also presents applications of plasmonic AuNS in bioimaging, photothermal therapy, and immunotherapy. An interesting advancement called Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) combines AuNS-mediated PTT with immunotherapy to enhance efficacy.
JOURNAL OF RAMAN SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Yuya Kanehira, Kosti Tapio, Gino Wegner, Sergio Kogikoski Jr, Sibylle Ruestig, Claudia Prietzel, Kurt Busch, Ilko Bald
Summary: A versatile generation of plasmonic nanoparticle dimers for surface-enhanced Raman scattering (SERS) is presented, which combines a DNA origami nanofork and spherical and nonspherical Au or Ag nanoparticles. By optimizing the plasmonic nanoparticle dimers for a specific excitation wavelength in SERS, the structures and measurement conditions with the highest SERS enhancement factors (EFs) suitable for single-molecule SERS (SM-SERS) are identified. Anisotropic nanoparticles with sharp edges, such as nanoflowers, increase the probability of placing single molecules in strongly enhancing hot spots for SM-SERS. The combination of a Ag nanoparticle and a Au nanoflower is the most versatile plasmonic dimer structure for SERS.
Article
Chemistry, Physical
Shinki, Jaspreet Singh, Subhendu Sarkar
Summary: A cost-effective wet chemical etching method was used to fabricate efficient SERS substrates by tuning the topographical aspects of Si pyramidal textures. The substrates with dense, small and uniformly sized pyramids exhibited a high enhancement factor when tested with Rh6G dye as an analyte molecule. Finite Difference Time Domain (FDTD) simulations confirmed the results, demonstrating the universal applicability of the proposed substrate.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Article
Nanoscience & Nanotechnology
B. Abasahl, C. Santschi, T. Raziman, O. J. F. Martin
Summary: The paper provides a detailed overview of nanofabrication techniques for plasmonics, focusing on two different approaches for the fabrication of metallic nanostructures based on e-beam lithography. Ion beam etching produces smaller and more regular features, while the lift-off process can result in slightly fuzzy nanoclusters on the substrate. Both techniques exhibit spectral differences in scattering cross sections for structures supporting complex resonances, guiding researchers to choose the best suited approach for a given application.
Article
Chemistry, Multidisciplinary
Yuhao Xu, Huatian Hu, Wen Chen, Pengfei Suo, Yuan Zhang, Shunping Zhang, Hongxing Xu
Summary: This study demonstrates the selective control of nonlinear surface-enhanced Raman scattering (SERS) enhancement in a phononic cavity optomechanical system by tuning the laser-plasmon detuning. The phononic nanodevice shows distinctive properties compared to the molecular system.
Article
Chemistry, Multidisciplinary
Peng Zheng, Lintong Wu, Piyush Raj, Takayuki Mizutani, Miklos Szabo, William A. Hanson, Ishan Barman
Summary: Small molecules play a crucial role in physiological regulation and pathological diagnosis, but their detection is challenging. Plasmonic immunoassays based on SERS offer high sensitivity, but are limited by intensity fluctuations and false signals. To overcome these issues, a dual-modal single-antibody approach (INSPIRE) is proposed for small molecule detection, which enables better concentration prediction and reduction of signal artifacts.
Article
Chemistry, Multidisciplinary
Jeongwon Kim, Sungwoo Lee, Jiwoong Son, Jieun Kim, Hajir Hilal, Minsun Park, Insub Jung, Jwa-Min Nam, Sungho Park
Summary: Rational design of plasmonic colloidal assemblies via bottom-up synthesis is challenging but can demonstrate unprecedented optical properties that are strongly related to the shape and spatial arrangement of the assembly. In this study, plasmonic cyclic Au nanosphere hexamers (PCHs) were successfully synthesized and showed excellent performance in single-particle surface-enhanced Raman scattering signals.