期刊
ACS NANO
卷 4, 期 6, 页码 3015-3022出版社
AMER CHEMICAL SOC
DOI: 10.1021/nn1002198
关键词
quantum dots; membrane nanotubes; intercellular transportation; single particle tracking; molecular motor
类别
资金
- National Basic Research Program of China [2007CB935601]
- National Natural Science Foundation of China [90713024, 30821001, 20821003]
- Chinese Academy of Sciences
- Chinese Ministry of Education [307001]
In this work, we reported that the quantum dot (QD) nanoparticles could be actively transported in the membrane nanotubes between cardiac myocytes. Single particle imaging and tracking of QDs revealed that most QDs moved in a bidirectional mode along the membrane nanotubes with a mean velocity of 1.23 mu m/s. The results suggested that QDs moving in the nanotubes were coordinately motivated by molecular motors. It provides new information for the study of intercellular transportation of nanoparticles.
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