Review
Chemistry, Inorganic & Nuclear
Masoumeh Mohamadhoseini, Zahra Mohamadnia
Summary: The article mainly discusses the different strategies of fabricating HG supramolecular self-healable materials using host-guest interactions between beta-CD and various guest molecules. Comparing different strategies helps to properly address the challenges of this field in the future.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Physical
Jaemin Kim, Jewon Choi, Kiho Park, Sungchan Kim, Kwan Woo Nam, Kookheon Char, Jang Wook Choi
Summary: Increasing the silicon content in the silicon-graphite composite anode to maximize the energy density of a lithium-ion battery cell is a challenging task due to the contradictory surface characteristics of silicon and graphite. This study presents an amphiphilic host-guest complex binder composed of pyrene-conjugated poly(acrylic acid) and a hyperbranched gamma-cyclodextrin polymer, which effectively maintains the integrity of the electrode and improves the cycling performance and rate capability of Si-Gr electrodes.
ADVANCED ENERGY MATERIALS
(2022)
Review
Chemistry, Inorganic & Nuclear
Guihua Fang, Xuewen Yang, Sumeng Chen, Qiuxiang Wang, Aiwen Zhang, Bo Tang
Summary: This review summarizes the application of CD-based host-guest supramolecular hydrogels in local drug delivery. It covers the formation of supramolecular hydrogels with different types of CD, the physicochemical characteristics of these hydrogels, and their application in various administration routes. The review also discusses the challenges and future directions for the clinical translation of CD-based host-guest supramolecular hydrogels.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Yuanyuan Li, Ziang Xu, Yahua Liu, Shijian Jin, Eric M. Fell, Baoguo Wang, Roy G. Gordon, Michael J. Aziz, Zhengjin Yang, Tongwen Xu
Summary: This study presents a strategy based on host-guest inclusion to acquire water-soluble ferrocene-based catholytes in a simple way. Factors determining the stability and electrochemical behavior of the inclusion complexes were identified.
Article
Chemistry, Applied
Elham Neisi, Abbas Dadkhah Tehrani, Hamid Reza Shamlouei
Summary: Supramolecular hydrogels have attracted significant attention due to their versatile approaches for preparation and new facile characterization strategies. In this study, we successfully formed a biocompatible and low-cost supramolecular hydrogel by binding modified cellulose nanowhiskers with gallic acid pendant groups (CNW-GA) with CNW grafted with beta-Cyclodextrin (CNW-g-beta-CD) through HG interaction. We also developed a simple colorimetric characterization method using phenolphthalein (PP) as a visual indicator for confirming HG complexation.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Physical
Fengyan Fang, Zhaolei Zhang, Pingping Zhang, Xiaokang Zhang, Hongchao Ma, Yanhui Wei
Summary: Cyclodextrin-based fluorescent probes have shown great potential in chemical or biological sensing. In this study, a new probe was developed by linking DASP and B-cyclodextrin. It was found that the intermolecular inclusion complex formed by the probe would disassemble in the presence of amantadine, leading to a decrease in fluorescence intensity. This discovery provides a rapid and selective method for the detection of amantadine and suggests the potential for designing other cyclodextrin-based sensing strategies.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2024)
Article
Multidisciplinary Sciences
Jintae Park, Jinwoo Park, Jinhoon Lee, Chanoong Lim, Dong Woog Lee
Summary: In this study, the interaction energies between cyclodextrin-modified surfaces and ditopic adamantane molecules in water were directly quantified using a surface forces apparatus. The adhesion energy of the beta-CD-DAd complex was found to increase significantly with increasing DAd concentration and reached saturation. The molecular adhesion energy of a single host-guest inclusion complex was evaluated to be approximately 9.51 k(B)T. This research provides fundamental information for further understanding of supramolecular chemistry and its applications.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Bo Huang, Zhe Tan
Summary: This study successfully loaded the air-sensitive cationic molecule magnesocene (MgCp2) into the three-dimensional pores of NH2-MIL-101(Al) using a gas-phase infiltration process, demonstrating a maximum loading of 43.1 wt %. It was also observed that MgCp2 covered the outside of Ni-MOF-74 due to its small one-dimensional channels.
INORGANIC CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Qin Wang, Xiao-Feng Wang, Wen-Qi Sun, Rui-Lian Lin, Ming-Fu Ye, Jing-Xin Liu
Summary: We demonstrated a novel supramolecular host-guest hydrogel, which is constructed by the complexation of the host gamma-CD with the guest 1-(4-carboxybenzyl)-4,4'-bipyridinium chloride through multiple interactions. The supramolecular hydrogel exhibits reversible electron transfer photochromic behavior and photomodulable fluorescence, making it suitable for visual display and anti-counterfeiting applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Alexandra N. Edelbrock, Tristan D. Clemons, Stacey M. Chin, Joshua J. W. Roan, Eric P. Bruckner, Zaida Alvarez, Jack F. Edelbrock, Kristen S. Wek, Samuel I. Stupp
Summary: The study reports a supramolecular system where interactions between peptide amphiphiles and beta-cyclodextrin with adamantane lead to the formation of a mechanically robust hydrogel with highly porous architecture, which can be 3D printed and exhibits significant bioactivity towards neurons. This nanostructured hydrogel based on supramolecular assembly has potential applications in neuronal research and biomaterial design.
Article
Chemistry, Physical
Enrique Sanchez Perez, Ritu Toor, Pierrick Bruyat, Celine Cepeda, Melissa Degardin, Jerome Dejeu, Didier Boturyn, Liliane Coche-Guerente
Summary: The study synthesized cyclodecapeptide scaffolds with two independent domains for multimeric presentation of guest molecules and potential grafting of biomolecules on solid surfaces. Using surface sensitive techniques, the influence of guest valency on the stability of inclusion complexes was quantified, showing a drastic enhancement of affinity with increasing guest valency. The results suggested that the multivalent model could be applied to extract intrinsic binding constants and effective concentrations of hosts.
Article
Chemistry, Multidisciplinary
Lubin Ni, Jie Gu, Xinyuan Jiang, Hongjie Xu, Zhen Wu, Yuchao Wu, Yi Liu, Ju Xie, Yongge Wei, Guowang Diao
Summary: A POM-CD-COSF crystalline structure was successfully obtained by self-assembling a Krebs-type POM, β-CD units, and two K4SiW12O40-type POMs. The POM-CD-COSF-based battery separator showed excellent performance in mitigating the polysulfide shuttle effect in lithium-sulfur batteries. This was attributed to the fast Li+ diffusion through the supramolecular channel of β-CD, efficient polysulfide-capture ability by the dynamic host-guest interaction of β-CD, and improved sulfur redox kinetics by the bidirectional catalysis of the POM cluster. This research opens up new possibilities for the development of multifunctional supramolecular POM frameworks and their applications in Li-S batteries.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Analytical
Rajamohan Rajaram, Subramania Angaiah, Yong Rok Lee
Summary: Nanofibers encapsulated with cyclodextrins enhance biological applications. Benzocaine forms host-guest complexes with 8-cyclodextrin, which are added to polyacrylonitrile solution for electrospinning. The resulting nanofibers show a uniform morphology and significantly smaller fiber diameter compared to free benzocaine. The host-guest complexes exhibit improved activity in terms of anti-inflammatory, anti-oxidant, and anti-diabetic effects.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Dongjing Zhang, Wenting Liang, Jigao Yi, Jinlei Chen, Yongjun Lv, Ting Zhao, Chao Xiao, Xiangyu Xie, Wanhua Wu, Cheng Yang
Summary: Photoirradiation of anthraquinone derivatives with gamma-cyclodextrin resulted in the formation of a gamma-CD derivative with a unique grafting at the 5'-position of one glucoside. Another anthraquinone entered the remaining space of the gamma-CD cavity to form a self-included quinhydrone charge transfer complex. The supramolecular complex showed high binding affinity and resistance to oxidation, and was applied in 3D photo-printing of soft materials.
SCIENCE CHINA-CHEMISTRY
(2022)
Article
Chemistry, Physical
Weilin Qi, Xuejiao Wang, Zeyu Liu, Kaerdun Liu, Yifan Long, Wanwan Zhi, Cheng Ma, Yun Yan, Jianbin Huang
Summary: Through self-assembly experiments, it was found that only ortho-xylene can form hydrogels with cyclodextrin due to its unique molecular conformation, which leads to a stable orientation in the cyclodextrin complex and ultimately gel formation.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Chun-Lin Chu, Jen-Yi Chang, Po-Yen Chen, Po-Yu Wang, Shu-Han Hsu, Dean Chou
Summary: In this study, horizontally stacked pure-Ge nanosheet gate-all-around field-effect transistors (GAA FETs) were developed by intentionally growing large lattice mismatch Ge/Si multilayers. The shape of Ge nanosheets was almost retained after etching due to excellent selectivity. Through forming gas annealing of the suspended Ge nanosheets, dislocations were easily removed, resulting in structures with excellent gate control and electrical properties.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Aldrik H. Velders, Michel Ossendrijver, Bart J. F. Keijser, Vittorio Saggiomo
Summary: A solution to the bottlenecks of centralized testing during the pandemic is presented, with a cheap and easy-to-produce noninstrumental device for at-home SARS-CoV2 RNA detection. This device, capable of maintaining isothermal conditions for LAMP tests, has minimal environmental impact and can be deployed on a large scale in a short amount of time.
Article
Chemistry, Multidisciplinary
Rebecca Kaup, Aldrik H. Velders
Summary: This study investigates the dynamics of polyamidoamine (PAMAM) dendrimer based micelles and shows that they can be manipulated by changing dendrimer generation, pH, and stoichiometry. The results reveal the exchange of dendrimers between micellar cores and demonstrate the importance of dendrimer generation, charge density, and stoichiometry in controlling the dynamics of complex coacervate core micelles.
Article
Biochemistry & Molecular Biology
Nikolas Duszenko, Danny M. van Willigen, Anton Bunschoten, Aldrik H. Velders, Meta Roestenberg, Fijs W. B. van Leeuwen
Summary: This study demonstrates that pathogen immunogenicity can be enhanced by complexing an adjuvant onto the surface of a poorly immunogenic bacterium. The adjuvanted bacteria were able to stimulate a stronger immune response and could potentially be used as a treatment modality to boost the immune system's response to pathogenic microbes.
Article
Chemistry, Physical
Laura M. I. Schijven, Vittorio Saggiomo, Aldrik H. Velders, Johannes H. Bitter, Constantinos V. Nikiforidis
Summary: Researchers have discovered that solid or hollow microparticles can be formed using proteins with different aggregate sizes. By mixing proteins with CaCl2 and Na2CO3 solutions, and then adding Au3+ ions, solid and hollow protein microparticles with embedded gold nanoparticles can be fabricated. This method has a broader range of applications, including biomaterial preparation and multimodal imaging.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Nataliia Berehova, Tessa Buckle, Maarten P. van Meerbeek, Anton Bunschoten, Aldrik H. Velders, Fijs W. B. van Leeuwen
Summary: The study aims to develop a dimeric tracer with superior affinity to support fluorescence-guided nerve-sparing surgery. Dimerization of the nerve-targeting peptide P0(101-125) proved to improve P0 targeting and enhance the pharmacokinetics and optical stability of the labeled compounds.
Article
Chemistry, Physical
Shih-Feng Tseng, Po-Shen Chen, Shu-Han Hsu, Wen-Tse Hsiao, Wei-Jei Peng
Summary: This study focuses on developing fiber laser-induced graphene (LIG) on polyimide films under different atmospheres. ZnO nanorods with a large specific surface area were synthesized via a cost-effective hydrothermal method. LIG surface with porous structures was used as a sensing layer for NO2 gas sensor by drop-casting ZnO nanorod sensing solution. The gas sensor fabricated in air showed outstanding sensing performance with high response (251.71%), fast response and recovery times (9.5 s and 8.3 s, respectively), and response stability at 1000 ppb NO2 concentration. The vacuum-fabricated ZnO gas sensor exhibited excellent sensitivity. These ZnO nanorod/LIG-based gas sensors can be combined with the Internet of Things for real-time detection of harmful gases.
APPLIED SURFACE SCIENCE
(2023)
Article
Automation & Control Systems
Shih-Feng Tseng, Yi-Hao Lin, Meng-Huan Zhou, Shu-Han Hsu, Wen-Tse Hsiao
Summary: This study synthesized Ti3C2Tx (MXene) through selective etching of Ti3AlC2 (MAX) using the in situ hydrofluoric acid method, and then grew ZnO on the Ti3C2Tx surface to form PEDOT:PSS/M-ZnO-based gas sensors. The M-ZnO composites were characterized using various techniques. The results showed that the PEDOT:PSS/M-ZnO-based gas sensor had the highest sensitivity of 10.61, which was 15.8 times higher than the PEDOT:PSS/ZnO-based gas sensor. Additionally, the PEDOT:PSS/M-ZnO-based gas sensor displayed good stability and excellent sensing selectivity for NO2 gas at room temperature.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Linh Chi T. Cao, Meng-Huan Zhou, Pakorn Opaprakasit, Paiboon Sreearunothai, Yuki Nagao, Sakoolkan Boonruang, Hoorieh Fallah, Shih-Feng Tseng, Shu-Han Hsu
Summary: This study explores the sensing response of different functionalization of specific sensing materials to achieve selective response to multiple gases. The introduction of TESPSA onto MXene-Ti3C2Tx forms COOH-Ti3C2Tx, which is alternately coated with PANI. This modification increases the gas binding sites and improves the binding strength of COOH-Ti3C2Tx/PANI to NH3 gas molecules, resulting in a high sensitivity (214.70 %) and fast gas response rate (1.75 % s(-1)).
ADVANCED MATERIALS INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Linh Chi T. Cao, Shu Han Hsu, Chun-Lin Chu
Summary: With the rise of the modern world, there is an increasing demand for broadband network systems in the high-tech industry. In order to meet the needs of intelligent life, unmanned devices, and vehicles, the development of the sixth-generation (6G) wireless system is integrating the functions of low-orbit satellites and 5G cellular communication systems. GaN/AlGaN/GaN (HEMTs) with wide bandgap and high-electron-mobility transistors are emerging as excellent candidates for 6G wireless technology due to their high-power-handling capabilities and small-scale fabrication. However, the conventional GaN/AlGaN/GaN HEMTs have limitations in device application and stability against temperature, which can be addressed by converting the gate-controlled channel from depletion- to enhancement mode using fluorine atoms.
Article
Automation & Control Systems
Romrawin Chumpu, Chun-Lin Chu, Tanyakarn Treeratanaphitak, Sanparith Marukatat, Shu-Han Hsu
Summary: This study accelerates the material selection process of microneedles using machine learning models and simulation data, and identifies the best model to predict the stress distribution of microneedles, improving experimental speed and efficiency.
ENGINEERING APPLICATIONS OF ARTIFICIAL INTELLIGENCE
(2023)
Article
Multidisciplinary Sciences
M. Victoria Gomez, Sander Baas, Aldrik H. Velders
Summary: Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique for molecular characterization and quantification, but is limited by poor sensitivity and expensive hardware. In this study, a microfluidic NMR-chip with a single planar-spiral microcoil and photochemically induced hyperpolarization is used for multidimensional and heteronuclear NMR experiments on picomole quantities of material. This chip significantly improves sensitivity and reduces cost and hardware complexity compared to traditional instruments.
NATURE COMMUNICATIONS
(2023)
Review
Materials Science, Multidisciplinary
Hoorieh Fallah, Luqman Hakim, Sakoolkan Boonruang, Waleed S. Mohammed, Shu Han Hsu
Summary: This review provides a comprehensive understanding of guided-mode resonance (GMR) technology, specifically focusing on polymer-based GMR sensors. It discusses the detection principle, device structures, and fabrication methods, as well as future development perspectives. Polymer-based GMR sensors offer flexibility, wearability, and integration, leading to improved technical characteristics and reduced costs.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Chun-Lin Chu, Guang-Li Luo, Dean Chou, Shu-Han Hsu
Summary: Monolayer doping technology enables the fabrication of devices with complex geometries, which could be utilized in next-generation semiconductor technology with improved short channel control.
ACS APPLIED ELECTRONIC MATERIALS
(2022)
Article
Materials Science, Biomaterials
Laura M. Schijven, Thomas D. Vogelaar, Simha Sridharan, Vittorio Saggiomo, Aldrik H. Velders, Johannes H. Bitter, Constantinos Nikiforidis
Summary: In this study, hollow microparticles (MPs) were formed by assembling lipoproteins in CaCO3 templates. The proteins interacted in the pores of the templates through hydrophobic forces, forming dense edges of the hollow MPs. Addition of Au3+ initiated a redox reaction that cross-linked the proteins, while forming gold nanoparticles (AuNPs). The resulting protein-based hollow MPs had a diameter of 6 μm and AuNPs embedded on their surface. This research suggests a new route for designing biobased Au-protein hollow MPs, enabling new possibilities for carrying functional molecules and bioimaging.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)