Article
Optics
Abey Issac, Saleem Al-Maskari, R. G. Sumesh Sofin, A. Ramadan Ibrahim, Osama K. Abou-Zied
Summary: The study investigates the photoluminescence quenching of nanoassemblies of CuInS2/ZnS quantum dots and rhodamine 560 molecules, revealing electron trapping as a key step in the nonradiative recombination pathway. Controlling trap density by varying dye loading enables modulation of this process, with electron trapping observed at different time scales. Furthermore, the excited state of CIS quantum dots is found to be vulnerable to the blinking process, affecting the fluorescence quantum yield.
JOURNAL OF LUMINESCENCE
(2021)
Article
Optics
Shikshita Jain, Shivani Bharti, Gurvir Kaur Bhullar, S. K. Tripathi
Summary: The study proposes a simple and reliable strategy for the aqueous synthesis of fluorescent CIS/ZnS core/shell NPs. The synthesized NPs exhibit good stability and suitability, making them promising candidates for biological and optoelectronic applications.
JOURNAL OF LUMINESCENCE
(2022)
Article
Chemistry, Physical
Bing Deng, Yanqing Zhu, Jingling Li, Xia Chen, Kun He, Juan Yang, Kaili Qin, Zhuoneng Bi, Xiudi Xiao, Shuaijun Chen, Xueqing Xu, Gang Xu
Summary: Efficient green light-emitting CuInS2/ZnS core/shell quantum dots were synthesized using a low temperature hot injection method, achieving high photoluminescence quantum yields and improved LED performance.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Spectroscopy
Sara Safari, Ahmad Amiri, Alireza Badiei
Summary: In this work, an efficient core-shell fluorescent quantum dots (QDs) probe based on CuInS2 (CIS) core and ZnS shell with the formula of CIS@ZnS QDs was synthesized and characterized. The probe shows a remarkable fluorescence response toward Aspartic Acid (Asp).
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Environmental Sciences
Beibei Xia, Guimiao Lin, Siman Zheng, Heng Zhang, Yangyang Yu
Summary: CuInS2/ZnS-PEG QDs have differential effects on the activation of human mast cells, inhibiting certain stimuli-induced degranulation and chemotaxis, while having varying effects on cell survival and the release of specific cytokines.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Haroon Rashid, Ants Koel, Toomas Rang, Nadeem Nasir, Nadeem Sabir, Faheem Ameen, Abher Rasheed
Summary: Quantum-dot-based core/shell structures have gained significance recently due to their optical, optoelectronic, and magnetic attributes. This study developed novel Cu-doped CdS/ZnS shell structures to enhance photoluminescence properties. Experimental results showed that Cu-doped ZnS shells adopted the crystal structure of CdS, minimizing lattice mismatch and offering better passivation, resulting in increased photoluminescence.
Article
Chemistry, Analytical
Daquan Li, Mei Huang, Ziyu Shi, Liang Huang, Jiening Jin, Chenxing Jiang, Wenbo Yu, Zhiyong Guo, Jing Wang
Summary: Antibiotics abuse poses a threat to human health and ecological environment. A competitive lateral flow immunoassay (CLFIA) platform with flexible readout was developed for the rapid detection of enrofloxacin. The platform utilizes three-dimensionally assembled gold nanoparticles as signal reporters, enabling qualitative screening and quantitative detection of enrofloxacin at low concentrations using the naked eye, optical scanner, or smartphone.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Feng Shao, Liqing Zheng, Jinggang Lan, Renato Zenobi
Summary: In this study, the local information of binary self-assembled monolayers (SAMs) on Au(111) coadsorbed from an equimolar mixture of p-cyanobenzenethiol (pCTP) and p-aminothiophenol (pATP) was investigated using tip-enhanced Raman spectroscopy (TERS) and density functional theory (DFT) calculations. The results revealed the coadsorption behavior, phase segregation, plasmon-induced photocatalysis, and solvation effects of the binary SAMs.
ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Jin Zhang, Yongli Mu, Mengqing Xu, Mohamed F. Foda, Heyou Han
Summary: The development of a simple small molecule chimeric peptide capable of sequential two-step self-assembly in tumor microenvironment has shown promising results in enhancing therapeutic efficacy. The aggregation of chimeric peptide in tumor cells accelerates drug internalization and improves photodynamic therapy outcomes, offering a new approach for constructing efficient theranostic agents.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Engineering, Biomedical
Zhaoyu Ma, Mohamed F. Foda, Yanli Zhao, Heyou Han
Summary: Rapid development of nanotechnology provides promising strategies in biomedicine, especially in tumor therapy. Improve cellular internalization from extracellular to intracellular via active targeting and enhance the intracellular retention of therapeutics by subcellular localization are crucial for the development of advanced anticancer nanosystems for strengthening the tumor therapy.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Engineering, Biomedical
Mengqing Xu, Jin Zhang, Yongli Mu, Mohamed Frahat Foda, Heyou Han
Summary: A study introduces an acid-responsive CaCO3 nanoparticle loaded with capsaicin that can specifically activate TRPV1 channels and trigger tumor calcium ion therapy. The nanoparticles have excellent biocompatibility and show potential for important clinical applications.
Article
Chemistry, Analytical
Jing Wang, Chenxing Jiang, Jingrui Yuan, Lu Tong, Yang Wang, Dinglv Zhuo, Weihong Ni, Jiafeng Zhang, Mei Huang, Daquan Li, Liang Huang, Bin Su, Jun Hu
Summary: A novel hue recognition competitive fluorescent lateral flow immunoassay strip has been developed for visual and quantitative detection of aflatoxin M1, with a low limit of detection and high accuracy.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Feng Shao, Jun Kit Wong, Qi Hang Low, Marcella Iannuzzi, Jingguo Li, Jinggang Lan
Summary: This study investigates the mechanism of CO reduction reaction on Cu single-crystal surfaces using in situ spectroscopy and ab initio molecular dynamics calculations. The intermediate species and Cu-O-ad/Cu-OHad species during CO adsorption, dimerization, oxidation, and hydrogenation were identified. The accurate vibrational frequencies of these intermediates were determined using AIMD simulations. These findings provide important insights into the CO(2)RR process and offer a spectroscopic tool for future mechanistic studies.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Chemistry, Multidisciplinary
Zhaoyu Ma, Mingkun Yang, Mohamed Frahat Foda, Kai Zhang, Shuting Li, Huageng Liang, Yanli Zhao, Heyou Han
Summary: By delivering vitamin C to the tumor site using responsive lipid nanoparticles, oxidative toxicity and polarization of M1 macrophages can be induced, promoting the infiltration of cytotoxic T lymphocytes in the tumor microenvironment and enhancing immune checkpoint blocking therapy. This approach shows better immune response than using clinical Anti-PD-L1 alone, providing a new therapeutic application for patients with clinically insensitive immunity.
Article
Chemistry, Multidisciplinary
Kai Zhang, Zhaoyu Ma, Shuting Li, Weiyun Zhang, Mohamed Frahat Foda, Yanli Zhao, Heyou Han
Summary: In this study, a biomimetic nanoflower platform with platelet membrane modification was developed for targeted delivery of anticoagulant drugs to treat both cancer and thrombosis, showing significant therapeutic efficacy and prolonged survival time.
Article
Chemistry, Multidisciplinary
Feng Shao, Zhaoming Xia, Futian You, Jun Kit Wong, Qi Hang Low, Hai Xiao, Boon Siang Yeo
Summary: In this study, we investigated the CO reduction reaction on Cu single-crystal surfaces using in situ electrochemical spectroscopy and density functional theory calculations. We identified coadsorbed and structure-/potential-dependent surface species, and found that the relative abundance of *OH follows a volcano trend with applied potentials in aqueous solutions. Combined with DFT calculations, we proposed that the surface H2O can serve as a strong proton donor for the first protonation step in both the C-1 and C-2 pathways of CORR at various applied potentials in alkaline electrolytes, leaving adsorbed *OH on the surface.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Applied
Xuqin Lv, Mohamed Frahat Foda, Jiangling He, Jiaojiao Zhou, Jie Cai
Summary: A label-free colorimetric aptasensor based on aptamer-enhanced oxidase-like activity of MnO2 nanoflowers is proposed for rapid and sensitive detection of OTA. The method exhibits good specificity and stability, and shows promising potential in the detection of mycotoxins in various samples.
Article
Nanoscience & Nanotechnology
Liang Huang, Ziyu Shi, Daquan Li, Chenxing Jiang, Xuexue Wang, Mei Huang, Jing Wang, Bin Su
Summary: A hue-recognition-based lateral flow immunoassay (HLFIA) has been developed for semi-quantitative detection of C-reactive protein (CRP) concentrations through modulation of emission from two nanoprobes, with high visual detection limit and linear range.
ACS APPLIED NANO MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Nesrein S. Salim, Mohamed Abdel-Alim, Huda E. M. Said, Mohamed F. Foda
Summary: This study aimed to investigate the phenolic and antioxidant properties of Egyptian Sonchus oleraceus leaves extract (SOE) while comparing its antihyperglycemic efficacy with conventional medicines. The results showed that SOE has rich phenolic and flavonoid compounds and significant antioxidant activity. In animal experiments, SOE significantly reduced blood glucose and lipid levels in diabetic rats, and improved liver and kidney functions. Histological analysis suggested the potential application of SOE as a diabetes treatment.
Article
Chemistry, Analytical
Lu Tong, Daquan Li, Mei Huang, Liang Huang, Jing Wang
Summary: In this study, a new intensified colorimetric label called SAAS was introduced, which combines the advantages of gold-silver alloy nanoparticles and a dendritic silica scaffold. The SAAS-based CLFIA strips achieved qualitative screening and precise quantification of aflatoxin B-1 (AFB(1)) at extremely low concentrations, and the signal-on configuration was enabled by leveraging SAAS as a quencher. The proposed nanohybrid labels have substantial potential in enhancing the sensitivity of CLFIA for detecting small molecules.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Feng Shao, Liqing Zheng, Jinggang Lan, Renato Zenobi
Summary: The study of binary thiolate self-assembled monolayers (SAMs) on metal surfaces provides insights into their coadsorption behavior and solvation effects. By employing tip-enhanced Raman spectroscopy (TERS) imaging and density functional theory (DFT) calculations, this research sheds light on the properties of these SAMs.
ANALYTICAL CHEMISTRY
(2022)
