Article
Nanoscience & Nanotechnology
Yan Wang, Luwei Zhang, Taka-Aki Asoh, Hiroshi Uyama
Summary: The study successfully synthesized chiral hierarchical porous monoliths in a flexible and highly efficient one-step method, without the need for complex doping or procedures. The monoliths exhibited hierarchical pore structure with throughpore and high surface area, and their porous structures and pore size could be adjusted by changing the conditions of phase separation. Additionally, the prepared monoliths showed good optical activity, thermal stability and mechanical properties, and were applied in enantioselective crystallization with promising performance.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Polymer Science
Randall A. Scanga, James F. Reuther
Summary: Significant advances have been made in the field of chiral helical polymers, with emergent properties of chiral nanoobjects derived from self-assembly and potential for new functional devices. Lessons from natural systems provide parallels and opportunities for further development in the field.
Article
Chemistry, Multidisciplinary
Soh Jin Mun, Yul Hui Shim, Geon Woong Kim, Sung Hwan Koo, Hyungju Ahn, Tae Joo Shin, Sang Ouk Kim, So Youn Kim
Summary: This study investigates the hierarchical structures of GO nematic liquid crystal phase during polymer crystallization using SAXS/WAXD techniques. It is found that the co-existence of GO LC and polymer crystals in GO/polymer complex influences the overall liquid crystallinity, with polymer crystallization affecting the microstructure of GO, especially in the case of interfacial crystallization. Furthermore, the interfacial crystallization of PEG on GO enhances both GO alignment and the orientation of PEG crystal.
Article
Chemistry, Organic
Zhen-Bang Chen, Ru-Xin Liu, Zi-Hao Li, Tong-Mei Ding, He-Yuan Bai, Zengming Shen, Shu-Yu Zhang
Summary: An efficient palladium-catalyzed enantioselective direct N-alkylation reaction using a novel axially chiral styrene-phosphine ligand SJTU-PHOS-1 was developed. The reaction showed good functional group compatibility and a wide range of substrate scope under mild conditions. Furthermore, DFT calculations revealed the coordination mode of the metal catalyst and the axially chiral styrene-phosphine ligand in enantioselectivity control.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Wei Gong, Zhijie Chen, Jinqiao Dong, Yan Liu, Yong Cui
Summary: Metal-organic frameworks (MOFs) or porous coordination polymers (PCPs), known for their high porosity and diverse functionality, have garnered significant interest. Chiral MOFs (CMOFs) have found wide applications in chiral recognition, separation, and catalysis. This review summarizes the recent progress in CMOFs, including design strategies, synthetic approaches, and cutting-edge applications, with a focus on asymmetric catalysis, enantioselective separation, enantioselective recognition, and sensing.
Article
Chemistry, Multidisciplinary
Meir Abuaf, Subhomoy Das, Yitzhak Mastai
Summary: Chiral polymeric particles (CPPs) have been extensively studied in recent years for their significance in pharmaceutical applications. In this study, nanosized CPPs were synthesized and applied as catalysts for direct asymmetric aldol reaction. The CPPs, prepared by miniemulsion or inverse miniemulsion methods using various chiral amino acid derivatives, were characterized by dynamic light scattering and scanning electron microscopy. The spherical nanoparticles with sizes between 250 and 400 nm and high chiral surface area served as catalysts in the aldol reaction at room temperature without additional solvent. Among them, l-tryptophan exhibited the highest enantiomeric excess (>86%) with similar catalytic performance for four times.
Article
Chemistry, Physical
Minami Odagi, Kazuo Nagasawa
Summary: This paper describes recent progress in chiral hypoiodite-catalyzed enantioselective oxidative bond-forming reactions, focusing on the applications of ammonium and guanidinium salts as onium iodites in carbon-oxygen, carbon-nitrogen, and carbon-carbon bond formation reactions.
Article
Multidisciplinary Sciences
Xin Zhang, Esther Cai Xia Ang, Ziqi Yang, Choon Wee Kee, Choon-Hong Tan
Summary: Chiral sulfur functional groups are often neglected in drug discovery, but they have the potential to expand the chemical space. In this study, we report a straightforward access to enantioenriched sulfinate esters using pentanidium as an organocatalyst. These sulfinate esters can be transformed into diverse chiral sulfur pharmacophores, demonstrating the viability of this approach towards sulfur stereogenic centers through late-stage diversification.
Review
Polymer Science
Ana M. Diez-Pascual
Summary: Graphene and its derivatives, when combined with polymers, form novel nanocomposites with enhanced properties, making them useful in various fields such as biomedicine, electronics, and energy storage. Functionalization methods have been utilized to improve the interaction between these nanocomposites and polymers.
Article
Chemistry, Organic
Qijian Ni, Zhiming Zhu, Yanjun Fan, Xiaoyun Chen, Xiaoxiao Song
Summary: The research has successfully developed an organocatalytic highly diastero- and enantioselective Friedel-Crafts conjugate addition method for adding indolizines to cyclopentenediones to obtain the desired products. The utility of the method was demonstrated through various late-stage functionalizations.
Review
Chemistry, Multidisciplinary
Hai Zhong, Biao Zhao, Jianping Deng
Summary: Chirality is a fundamental feature of living organisms and integrating magnetic nanoparticles with chirality can create advanced multi-functional materials. This review article summarizes recent progress in constructing chiral magnetic hybrid materials using macromolecules, and discusses their applications in various chiral research fields.
Article
Chemistry, Multidisciplinary
Dandan Miao, Vanessa Di Michele, Felix Gagnon, Cyril Aumaitre, Andrea Lucotti, Mirella Del Zoppo, Frederic Lirette, Matteo Tommasini, Jean-Francois Morin
Summary: Linear and helical graphene nanoribbons with electron-rich pyrrole units were synthesized using photochemical cyclodehydrochlorination reaction. These nanoribbons exhibited excellent conductivity and fluorescence sensing properties, making them suitable for detecting TNT.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Sabrin Al-Fogra, Bowen Yang, Lisa Jurkiewicz, Frank Hauke, Andreas Hirsch, Tao Wei
Summary: This study presents a facile and universal laser writing approach for covalent patterning of graphene, leading to the formation of graphene architectures consisting of antaratopically functionalized superlattices, which were previously elusive.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Analytical
Datong Wu, Cong Ma, Ting Wan, Pengfen Zhu, Yong Kong
Summary: In this study, an ionic helical polymer with right-or left-handed configuration was prepared and characterized for its structure and absolute handedness. The polymer was found to be effective as an electrochemical enantioselector for chiral electroanalysis, capable of recognizing different configurations of amino acids. This research offers great promise for the synthesis and application of ionic helical polymers with multiple stereogenic centers.
ANALYTICA CHIMICA ACTA
(2022)
Article
Multidisciplinary Sciences
Zizhao Huang, Zhenyi He, Bingbing Ding, He Tian, Xiang Ma
Summary: The development of pure organic room-temperature phosphorescent materials with circularly polarized luminescence has greatly facilitated the integration and systemization of luminescent materials in various science and technological applications. In this study, a type of photoinduced circularly polarized phosphorescent material was constructed by dispersing phosphorescent chiral helical substituted polyacetylenes into a processable poly(methyl methacrylate) (PMMA) matrix. These materials exhibit high absorption and luminescent dissymmetric factors, and also possess dynamic chiro-optical functionality under UV light irradiation.
NATURE COMMUNICATIONS
(2022)