Application of Quality by Design to the Process Development of Botanical Drug Products: A Case Study

Solubilities of Protocatechuic Aldehyde, Caffeic Acid, d-Galactose, and d-Raffinose Pentahydrate in Ethanol–Water Solutions

(2012) Lei Zhang et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Synergistic interaction between Astragali Radix and Rehmanniae Radix in a Chinese herbal formula to promote diabetic wound healing

(2012) Kit-Man Lau et al.   JOURNAL OF ETHNOPHARMACOLOGY

Terpenes from Copaifera Demonstrated in Vitro Antiparasitic and Synergic Activity

(2012) Erika Izumi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synergism of plant-derived polyphenols in adipogenesis: Perspectives and implications

(2012) María Herranz-López et al.   PHYTOMEDICINE

Development of a Design Space for a Unit Operation: Illustration Using Compression-Mix Blending Process for the Manufacture of a Tablet Dosage Form

(2012) Shiva G. Kapsi et al.   Journal of Pharmaceutical Innovation

Utility of Physiologically Based Absorption Modeling in Implementing Quality by Design in Drug Development

(2011) Xinyuan Zhang et al.   AAPS Journal

Application of Pharmaceutical QbD for Enhancement of the Solubility and Dissolution of a Class II BCS Drug using Polymeric Surfactants and Crystallization Inhibitors: Development of Controlled-Release Tablets

(2011) Emad B. Basalious et al.   AAPS PHARMSCITECH

In-line monitoring of alcohol precipitation by near-infrared spectroscopy in conjunction with multivariate batch modeling

(2011) Hongxia Huang et al.   ANALYTICA CHIMICA ACTA

Solid-Liquid Equilibria of D-Glucose, D-Fructose and Sucrose in the Mixture of Ethanol and Water from 273.2 K to 293.2 K

(2011) Xingchu GONG et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Comparison of Two Separation Technologies Applied in the Manufacture of Botanical Injections: Second Ethanol Precipitation and Solvent Extraction

(2011) Xingchu Gong et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Isothermal Microcalorimetry as a Quality by Design Tool to Determine Optimal Blending Sequences

(2010) M. H. D. Kamal Al-Hallak et al.   AAPS Journal

An integrated Quality by Design (QbD) approach towards design space definition of a blending unit operation by Discrete Element Method (DEM) simulation

(2010) Siegfried Adam et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Sugar Conversion Induced by the Application of Heat to Grape Must

(2010) Pasquale M. Falcone et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Design Space of Pharmaceutical Processes Using Data-Driven-Based Methods

(2010) Fani Boukouvala et al.   Journal of Pharmaceutical Innovation

Quality by design case study: An integrated multivariate approach to drug product and process development

(2009) Jun Huang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Purification of a Water Extract of Chinese Sweet Tea Plant (Rubus suavissimusS. Lee) by Alcohol Precipitation

(2009) Gar Yee Koh et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Genotoxic activities of the food contaminant 5-hydroxymethylfurfural using different in vitro bioassays

(2009) Isabelle Severin et al.   TOXICOLOGY LETTERS

Rapid quantification of iridoid glycosides analogues in the formulated Chinese medicine Longdan Xiegan Decoction using high-performance liquid chromatography coupled with mass spectromentry

(2008) Li Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen)

(2008) Yong-Guo Li et al.   JOURNAL OF CHROMATOGRAPHY A

Characterization of saccharides and phenolic acids in the Chinese herb Tanshen by ESI-FT-ICR-MS and HPLC

(2008) Huilin Li et al.   JOURNAL OF MASS SPECTROMETRY

Pharmaceutical Quality by Design: Product and Process Development, Understanding, and Control

(2008) Lawrence X. Yu   PHARMACEUTICAL RESEARCH

PQLI Design Space

(2008) John Lepore et al.   Journal of Pharmaceutical Innovation