Gene-Directed Enzyme Prodrug Therapy

Neural Stem Cell-Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies

(2013) K. S. Aboody et al.   Science Translational Medicine

Bone marrow-derived mesenchymal stem cells promote growth and angiogenesis of breast and prostate tumors

(2013) Ting Zhang et al.   Stem Cell Research & Therapy

Neural Stem Cell-Mediated Delivery of Irinotecan-Activating Carboxylesterases to Glioma: Implications for Clinical Use

(2013) Marianne Z. Metz et al.   Stem Cells Translational Medicine

Suicide gene therapy in cancer: Where do we stand now?

(2012) Sónia Duarte et al.   CANCER LETTERS

Mesenchymal Stem Cell 1 (MSC1)-Based Therapy Attenuates Tumor Growth Whereas MSC2-Treatment Promotes Tumor Growth and Metastasis

(2012) Ruth S. Waterman et al.   PLoS One

IL-7 receptor expression identifies suicide gene-modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors

(2011) A. Bondanza et al.   BLOOD

Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma

(2011) E. Antonio Chiocca et al.   JOURNAL OF CLINICAL ONCOLOGY

In vivo MR tracking of therapeutic microglia to a human glioma model

(2011) Emeline J. Ribot et al.   NMR IN BIOMEDICINE

A phase I clinical trial of thymidine kinase-based gene therapy in advanced hepatocellular carcinoma

(2010) B Sangro et al.   CANCER GENE THERAPY

E-cadherin contributes to the bystander effect of TK/GCV suicide therapy and enhances its antitumoral activity in pancreatic cancer models

(2010) L Garcia-Rodríguez et al.   GENE THERAPY

Efficient gene transfer using the human JC virus-like particle that inhibits human colon adenocarcinoma growth in a nude mouse model

(2010) L-S Chen et al.   GENE THERAPY

Side populations of glioblastoma cells are less sensitive to HSV-TK/GCV suicide gene therapy system than the non-side population

(2010) Weiwei Hu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma

(2010) Fernanda I. Staquicini et al.   JOURNAL OF CLINICAL INVESTIGATION

Silk-elastinlike protein polymers improve the efficacy of adenovirus thymidine kinase enzyme prodrug therapy of head and neck tumors

(2010) Khaled Greish et al.   JOURNAL OF GENE MEDICINE

Prevention of intrahepatic metastasis of liver cancer by suicide gene therapy and chemokine ligand 2/monocyte chemoattractant protein-1 delivery in mice

(2010) Kaheita Kakinoki et al.   JOURNAL OF GENE MEDICINE

Concise Review: Dissecting a Discrepancy in the Literature: Do Mesenchymal Stem Cells Support or Suppress Tumor Growth?

(2010) Ann H. Klopp et al.   STEM CELLS

Advances in mesenchymal stem cell-mediated gene therapy for cancer

(2010) Roisin M Dwyer et al.   Stem Cell Research & Therapy

Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors

(2009) F Xu et al.   CANCER GENE THERAPY

A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer

(2009) Wei Tang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A Phase I/II Clinical Trial in Localized Prostate Cancer of an Adenovirus Expressing Nitroreductase with CB1984

(2009) Prashant Patel et al.   MOLECULAR THERAPY

Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy

(2009) Gabi Dachs et al.   MOLECULES

Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging

(2009) Shannon Kidd et al.   STEM CELLS