Antitumor Activity of Gemcitabine Can Be Potentiated in Pancreatic Cancer through Modulation of TLR4/NF-κB signaling by 6-Shogaol

Gemcitabine-Based Chemogene Therapy for Pancreatic Cancer Using Ad-dCK::UMK GDEPT and TS/RR siRNA Strategies

(2015) Soukaina Réjiba et al.   NEOPLASIA

6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ)

(2013) Boon Shing Tan et al.   CANCER LETTERS

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

(2012) Rong Hu et al.   PLoS One

Polymorphisms of theTLR2andTLR4genes are associated with risk of gastric cancer in a Brazilian population

(2012) Juliana Garcia de Oliveira   WORLD JOURNAL OF GASTROENTEROLOGY

6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-κB activation

(2010) H Ling et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of NF-κB by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4

(2010) Jianghua Wang et al.   CANCER RESEARCH

Expression and significance of TLR4 and HIF-1α in pancreatic ductal adenocarcinoma

(2010) Jian-Jun Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

TBK1-Targeted Suppression of TRIF-Dependent Signaling Pathway of Toll-Like Receptors by 6-Shogaol, an Active Component of Ginger

(2009) Se-Jeong PARK et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Antitumor Activity of Gemcitabine and Oxaliplatin Is Augmented by Thymoquinone in Pancreatic Cancer

(2009) Sanjeev Banerjee et al.   CANCER RESEARCH

6-Shogaol, an Active Constituent of Dietary Ginger, Induces Autophagy by Inhibiting the AKT/mTOR Pathway in Human Non-Small Cell Lung Cancer A549 Cells

(2009) Jen-Yu Hung et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lipopolysaccharide (LPS) increases the invasive ability of pancreatic cancer cells through the TLR4/MyD88 signaling pathway

(2009) Mio Ikebe et al.   JOURNAL OF SURGICAL ONCOLOGY

Inhibition of homodimerization of toll-like receptor 4 by 6-shogaol

(2009) Sang-Il Ahn et al.   MOLECULES AND CELLS

Garlic (Allium sativum) Extract Inhibits Lipopolysaccharide-Induced Toll-Like Receptor 4 Dimerization

(2008) Hyung-Sun YOUN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Specific reaction of α,β-unsaturated carbonyl compounds such as 6-shogaol with sulfhydryl groups in tubulin leading to microtubule damage

(2008) Kazuhiro Ishiguro et al.   FEBS LETTERS

Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization

(2007) Hyung S. Youn et al.   BIOCHEMICAL PHARMACOLOGY