TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages

(2017) Jennifer L. Guerriero et al.   NATURE

Data-analysis strategies for image-based cell profiling

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Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging

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Anti-tumor Activity of Toll-Like Receptor 7 Agonists

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Biophysical and biomolecular determination of cellular age in humans

(2017) Jude M. Phillip et al.   Nature Biomedical Engineering

Image based Machine Learning for identification of macrophage subsets

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Topical treatment of melanoma metastases with imiquimod, plus administration of a cancer vaccine, promotes immune signatures in the metastases

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Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

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Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes

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Analysis of nanoparticle delivery to tumours

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Supramolecular Guest–Host Interactions for the Preparation of Biomedical Materials

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Macrophages and Therapeutic Resistance in Cancer

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ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

(2015) Juan R. Cubillos-Ruiz et al.   CELL

Designing polymers with sugar-based advantages for bioactive delivery applications

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The interaction of anticancer therapies with tumor-associated macrophages

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In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Understanding Local Macrophage Phenotypes In Disease: Modulating macrophage function to treat cancer

(2015) Vincenzo Bronte et al.   NATURE MEDICINE

Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients

(2015) Jason L. Gaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

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The future of immune checkpoint therapy

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Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle

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Sustained small molecule delivery from injectable hyaluronic acid hydrogels through host–guest mediated retention

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Novel Markers to Delineate Murine M1 and M2 Macrophages

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CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

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Dependence of optical scattering from Intralipid in gelatin-gel based tissue-mimicking phantoms on mixing temperature and time

(2014) Puxiang Lai et al.   JOURNAL OF BIOMEDICAL OPTICS

Effective Innate and Adaptive Antimelanoma Immunity through Localized TLR7/8 Activation

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Imaging macrophages with nanoparticles

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Environment-responsive nanophores for therapy and treatment monitoring via molecular MRI quenching

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Cyclodextrin-based supramolecular systems for drug delivery: Recent progress and future perspective

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Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

(2013) Rebecca S. Cook et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Modulation of macrophage phenotype by cell shape

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Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo

(2013) Greg M. Thurber et al.   Nature Communications

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages

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Macrophage plasticity and polarization: in vivo veritas

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The pharmacokinetics of Toll-like receptor agonists and the impact on the immune system

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Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

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Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

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Alternative Activation of Macrophages: Mechanism and Functions

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Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

(2010) Christian Steidl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Imiquimod Enhances IFN-γ Production and Effector Function of T Cells Infiltrating Human Squamous Cell Carcinomas of the Skin

(2009) Susan J. Huang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition

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Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

(2009) Thouis R. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE