Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma

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Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response

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Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas

(2018) Christopher W. Mount et al.   NATURE MEDICINE

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

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Immune microenvironment of gliomas

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Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study

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A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG)

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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy

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The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

NKG2D ligand expression in pediatric brain tumors

(2016) Kristen Haberthur et al.   CANCER BIOLOGY & THERAPY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology

(2015) Ganesh M. Shankar et al.   ACTA NEUROPATHOLOGICA

High frequency of H3F3A K27M mutations characterizes pediatric and adult high-grade gliomas of the spinal cord

(2015) Marco Gessi et al.   ACTA NEUROPATHOLOGICA

Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas

(2015) Stephanie Puget et al.   CHILDS NERVOUS SYSTEM

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

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Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization

(2015) Jason H. Stafford et al.   NEURO-ONCOLOGY

Immunosuppressive mechanisms in glioblastoma: Fig. 1.

(2015) Edjah K. Nduom et al.   NEURO-ONCOLOGY

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Human pontine glioma cells can induce murine tumors

(2014) Viola Caretti et al.   ACTA NEUROPATHOLOGICA

CNS macrophages and peripheral myeloid cells in brain tumours

(2014) Rainer Glass et al.   ACTA NEUROPATHOLOGICA

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

(2014) Pawel Buczkowicz et al.   NATURE GENETICS

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

(2014) Kathryn R Taylor et al.   NATURE GENETICS

Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

(2014) Adam M Fontebasso et al.   NATURE GENETICS

Time to rethink the unthinkable: Upfront biopsy of children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)

(2014) Mark W. Kieran   PEDIATRIC BLOOD & CANCER

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children

(2013) Tene A. Cage et al.   CHILDS NERVOUS SYSTEM

Characterization of Distinct Immunophenotypes across Pediatric Brain Tumor Types

(2013) A. M. Griesinger et al.   JOURNAL OF IMMUNOLOGY

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

(2012) Dong-Anh Khuong-Quang et al.   ACTA NEUROPATHOLOGICA

Immune genes are associated with human glioblastoma pathology and patient survival

(2012) Elodie Vauléon et al.   BMC Medical Genomics

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Diffuse intrinsic pontine gliomas: A systematic update on clinical trials and biology

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH