期刊
MSYSTEMS
卷 3, 期 2, 页码 -出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/mSystems.00168-17
关键词
aphids; citrus greening; plant virus; proteomics; psyllids; transcriptomics; vector biology
类别
资金
- California Citrus Research Board
- National Science Foundation
- USDA NIFA
- USDA ARS
- Cornell University
- Boyce Thompson Institute
Insect-vectored pathogens pose one of the greatest threats to plant and animal, including human, health on a global scale. Few effective control strategies have been developed to thwart the transmission of any insect-transmitted pathogen. Most have negative impacts on the environment and human health and are unsustainable. Plant pathogen transmission by insect vectors involves a combination of coevolving biological players: plant hosts, insect vectors, plant pathogens, and bacterial endosymbionts harbored by the insect. Our ability to help growers to control vector-borne disease depends on our ability to generate pathogen-and/or disease-resistant crops by traditional or synthetic approaches and to block pathogen transmission by the insect vector. Systems biology studies have led to the reexamination of existing paradigms on how pathogens interact with insect vectors, including the bacterial symbionts, and have identified vector-pathogen interactions at the molecular and cellular levels for the development of novel transmission interdiction strategies.
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