Article
Peripheral Vascular Disease
Swati Sakhuja, Calvin L. Colvin, Oluwasegun P. Akinyelure, Byron C. Jaeger, Kathryn Foti, Suzanne Oparil, Shakia T. Hardy, Paul Muntner
Summary: The study found that a higher proportion of US adults were aware but not treated for hypertension, with some of them being unaware of their condition. Characteristics associated with not being aware of hypertension or not receiving treatment were identified through the National Health and Nutrition Examination Surveys from 2015 to 2018.
Article
Health Care Sciences & Services
Sarah H. Cross, Brystana G. Kaufman, Tammie E. Quest, Haider J. Warraich
Summary: The study found that deaths in hospice facilities increased among all patient groups, but there were significant differences in age, sex, race, marital status, education level, cause of death, and geography. These disparities warrant further examination.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2021)
Review
Medicine, General & Internal
Alex H. Krist, Karina W. Davidson, Carol M. Mangione, Michael J. Barry, Michael Cabana, Aaron B. Caughey, Katrina Donahue, Chyke A. Doubeni, John W. Epling, Martha Kubik, Gbenga Ogedegbe, Lori Pbert, Michael Silverstein, Melissa A. Simon, Chien-Wen Tseng, John B. Wong
Summary: This recommendation advises against screening for asymptomatic carotid artery stenosis in the general adult population due to the harms outweighing the benefits.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Environmental Sciences
Shiwei Yan, Cong Hu, Yu Wang, Jian Gao, Ziqi Wang, Tianshu Han, Changhao Sun, Wenbo Jiang
Summary: There is limited research on the relationship between phthalate metabolites and mortality among people with hypertension. This study found that higher levels of specific phthalates are significantly associated with increased risks of all-cause, cardiovascular disease, and cancer mortality among people with hypertension.
Article
Endocrinology & Metabolism
Bo-Yeon Kim, Ji-In Lee, Hye-Mi Lee, So Hun Kim, Eun Yeong Mo, Jang Won Son, Sihoon Lee, Sungrae Kim
Summary: This study aimed to investigate the optimal blood pressure target in Korean individuals with type 2 diabetes mellitus (T2DM) and analyze its relationship with cardio-renal events and all-cause mortality. The results showed that an SBP of 120-129 mmHg and a DBP of 75-79 mmHg were associated with the lowest risk of all-cause mortality. Lower SBP may be beneficial for patients with T2DM at high risk of renal disease.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Cardiac & Cardiovascular Systems
Jiake Wu, Weili Duan, Yundi Jiao, SiTong Liu, LiQiang Zheng, YingXian Sun, ZhaoQing Sun
Summary: Stage 1 hypertension is significantly associated with an increased risk of cardiovascular disease mortality and stroke among rural women aged 45 years and older in Liaoning province, China. However, no increased risk of cardiovascular disease was observed in participants aged 35-44 years with stage 1 hypertension.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Sean D. Connolly, Donald M. Lloyd-Jones, Hongyan Ning, Bradley S. Marino, Lindsay R. Pool, Amanda M. Perak
Summary: There is an association between social determinants of health and cardiovascular health among US adolescents, with varying degrees of association between different racial and ethnic groups.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Shinjeong Song, Hye Ah Lee, Yeji Kim, Bo Kyung Jeon, Chang Mo Moon, Junbeom Park
Summary: This study aimed to examine the association between dynamic smoking habit change and cardiovascular risk in a population newly diagnosed with hypertension, diabetes, and dyslipidemia. The results showed that worsening of smoking habits was associated with an increased risk of cardiovascular events and death.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Letter
Medicine, General & Internal
Thomas N. Vilches, Seyed M. Moghadas, Pratha Sah, Meagan C. Fitzpatrick, Affan Shoukat, Abhishek Pandey, Alison P. Galvani
Summary: This decision analytic modeling study utilizes a simulation model to assess the link between US COVID-19 vaccination campaigns and the occurrences of infections, hospitalizations, and deaths.
Article
Peripheral Vascular Disease
Seyed Saeed Tamehri Zadeh, Seyyed Saeed Moazzeni, Kunihiro Matsushita, Mitra Hasheminia, Fereidoun Azizi, Farzad Hadaegh
Summary: This study evaluated the association between hypertension and cardiovascular disease in the adult population of Tehran. The findings suggest that age is an important factor in determining the relationship between hypertension and cardiovascular disease risk.
JOURNAL OF HYPERTENSION
(2022)
Article
Medicine, General & Internal
Steven A. Sumner, Daniel Bowen, Kristin Holland, Marissa L. Zwald, Alana Vivolo-Kantor, Gery P. Guy, William J. Heuett, DeMia P. Pressley, Christopher M. Jones
Summary: This study developed a statistical model using proxy data sources to estimate the national opioid overdose mortality rate in real time. Compared to traditional forecasting models, this machine learning-based approach showed higher accuracy in weekly predictions.
Article
Cardiac & Cardiovascular Systems
Jennifer A. Davidson, Amitava Banerjee, Ian Douglas, Clemence Leyrat, Richard Pebody, Helen McDonald, Emily Herrett, Harriet Forbes, Liam Smeeth, Charlotte Warren-Gash
Summary: This study reveals that the incidence of first myocardial infarction and stroke is reduced 1-3 months after influenza vaccination. However, it is still unclear how underlying cardiovascular risk affects this association.
EUROPEAN HEART JOURNAL
(2023)
Article
Peripheral Vascular Disease
Paul Muntner, Miriam A. Miles, Byron C. Jaeger, Lonnie Hannon, Shakia T. Hardy, Yechiam Ostchega, Gregory Wozniak, Joseph E. Schwartz
Summary: According to the National Health and Nutrition Examination Survey data, the proportion of US adults with hypertension that have controlled blood pressure has declined. This decline is particularly significant among older adults, women, and non-Hispanic black adults.
Article
Cardiac & Cardiovascular Systems
Wenzhen Li, Dajie Chen, Shuai Liu, Xiaojun Wang, Xiaojie Chen, Jiafeng Chen, Jing Ma, Fujian Song, Hui Li, Shijiao Yan, Xiaoxv Yin, Shiyi Cao, Yanhong Gong, Junan Liu, Wei Yue, Feng Yan, Chuanzhu Lv, Zhihong Wang, Zuxun Lu
Summary: After the update of the hypertension definition by the 2017 ACC/AHA guidelines, the prevalence of hypertension significantly increased, with newly labeled as hypertensive mainly seen in north China. Efforts should focus on improving health education, management, and interventions in the northern region.
Article
Health Care Sciences & Services
Shujing Wu, Yu Xu, Ruizhi Zheng, Jieli Lu, Mian Li, Li Chen, Yanan Huo, Min Xu, Tiange Wang, Zhiyun Zhao, Shuangyuan Wang, Hong Lin, Meng Dai, Di Zhang, Jingya Niu, Guijun Qin, Li Yan, Qin Wan, Lulu Chen, Lixin Shi, Ruying Hu, Xulei Tang, Qing Su, Xuefeng Yu, Yingfen Qin, Gang Chen, Zhengnan Gao, Guixia Wang, Feixia Shen, Zuojie Luo, Yuhong Chen, Yinfei Zhang, Chao Liu, Youmin Wang, Shengli Wu, Tao Yang, Qiang Li, Yiming Mu, Jiajun Zhao, Yufang Bi, Weiqing Wang, Guang Ning
Summary: This study examines the association between updated blood pressure categories and the risk of cardiovascular diseases, and finds that improving cardiovascular health can attenuate the risk of cardiovascular events in individuals with stage 1 hypertension, especially in adults under the age of 60.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2022)
Article
Biology
Jun Wang, Fangchao Liu, Jianxin Li, Keyong Huang, Xueli Yang, Jichun Chen, Xiaoqing Liu, Jie Cao, Shufeng Chen, Chong Shen, Ling Yu, Fanghong Lu, Xianping Wu, Liancheng Zhao, Ying Li, Dongsheng Hu, Jianfeng Huang, Dongfeng Gu, Xiangfeng Lu
Summary: The study revealed a negative association between increasing fruit and vegetable consumption and the risk of cardiovascular disease and all-cause mortality. Particularly, higher consumption of fruit was found to have a significant role in preventing cardiovascular disease and premature mortality. However, the association with vegetable consumption did not show a significant impact on these risks.
SCIENCE CHINA-LIFE SCIENCES
(2022)
Article
Urology & Nephrology
Nisha Bansal, Leila R. Zelnick, Christie M. Ballantyne, Paulo H. M. Chaves, Robert H. Christenson, Josef Coresh, Christopher R. deFilippi, James A. de Lemos, Lori B. Daniels, Alan S. Go, Jiang He, S. Susan Hedayati, Kunihiro Matsushita, Vijay Nambi, Michael G. Shlipak, Jonathan J. Taliercio, Stephen L. Seliger
Summary: This study analyzed the distribution of NT-proBNP and hsTnT in CKD patients and found that the utility of conventional upper reference limits for these biomarkers remains debatable. It suggests that developing eGFR-specific thresholds may improve the diagnostic value of these biomarkers for heart failure and myocardial infarction in CKD patients.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Urology & Nephrology
Insa M. Schmidt, Anand Srivastava, Venkata Sabbisetti, Gearoid M. McMahon, Jiang He, Jing Chen, John W. Kusek, Jonathan Taliercio, Ana C. Ricardo, Chi-yuan Hsu, Paul L. Kimmel, Kathleen D. Liu, Theodore E. Miff, Robert G. Nelson, Ramachandran S. Vasan, Dawei Xie, Xiaoming Zhang, Ragnar Palsson, Isaac E. Stillman, Helmut G. Rennke, Harold I. Feldman, Joseph V. Bonventre, Sushrut S. Waikar
Summary: Plasma KIM-1 levels are associated with clinical outcomes and pathological lesions in various kidney diseases, with higher levels of plasma KIM-1 being linked to an increased risk of kidney failure.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2022)
Article
Neurosciences
Bizhong Che, Haichang Chen, Aili Wang, Hao Peng, Xiaoqing Bu, Jintao Zhang, Zhong Ju, Tan Xu, Jiang He, Chongke Zhong, Yonghong Zhang
Summary: This study found an inverse association between plasma L-carnitine and cognitive impairment after ischemic stroke. Additionally, the addition of L-carnitine significantly improved the risk reclassification for cognitive impairment. Furthermore, a joint effect of L-carnitine and inflammation markers was observed, indicating a potential influence on the risk of poststroke cognitive impairment.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Statistics & Probability
Yujia Cheng, Yang Li, Matthew Lee Smith, Changwei Li, Ye Shen
Summary: This study examines the handling of missing data in fall prevention programs for older adults and compares the performance of multiple imputation-stepwise regression and multiple imputation-least absolute shrinkage and selection operator methods in variable selection. Simulation studies were conducted to evaluate their performances.
JOURNAL OF APPLIED STATISTICS
(2023)
Article
Peripheral Vascular Disease
Xiaomei Lu, Bin Yang, Huijun Yang, Laiyuan Wang, Hongfan Li, Shufeng Chen, Xiangfeng Lu, Dongfeng Gu
Summary: This study identifies miR-320b as a novel regulator of macrophage cholesterol efflux and suggests it as a potential therapeutic target for atherosclerosis treatment.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2022)
Article
Urology & Nephrology
Joshua D. Bundy, Mahboob Rahman, Kunihiro Matsushita, Byron C. Jaeger, Jordana B. Cohen, Jing Chen, Rajat Deo, Mirela A. Dobre, Harold I. Feldman, John Flack, Radhakrishna R. Kallem, James P. Lash, Stephen Seliger, Tariq Shafi, Shoshana J. Weiner, Myles Wolf, Wei Yang, Norrina B. Allen, Nisha Bansal, Jiang He, CRIC Study Investigators
Summary: This study developed 10-year ASCVD risk prediction models in patients with CKD, including novel biomarkers, which performed better than models using only traditional risk factors developed for the general population.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Geriatrics & Gerontology
Adrianna Westbrook, Ruiyuan Zhang, Mengyao Shi, Alexander C. Razavi, Zhijie Huang, Jing Chen, Jiang He, Tanika Kelly, Ye Shen, Changwei Li
Summary: This study aimed to evaluate the association between baseline telomere length and kidney function. The results showed that participants with longer telomere length were more likely to have consistently normal kidney function, while it was not associated with the rate of eGFR change.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Immunology
Yaling Lu, Yu Zhao, Qi Zhang, Chongquan Fang, Anran Bao, Wenjing Dong, Yanbo Peng, Hao Peng, Zhong Ju, Jiang He, Yonghong Zhang, Tan Xu, Chongke Zhong
Summary: Elevated levels of plasma sTREM2 are independently associated with increased risks of death and cardiovascular events in acute ischemic stroke (AIS) patients. Incorporating sTREM2 into traditional risk factor models significantly improves risk prediction for death and cardiovascular events.
JOURNAL OF NEUROINFLAMMATION
(2022)
Article
Urology & Nephrology
Ian E. McCoy, Jesse Y. Hsu, Joseph Bonventre, Chirag R. Parikh, Alan S. Go, Kathleen D. Liu, Ana C. Ricardo, Anand Srivastava, Debbie L. Cohen, Jiang He, Jing Chen, Panduranga S. Rao, Chi-Yuan Hsu
Summary: Hospitalized acute kidney injury (AKI) is associated with long-term changes in kidney injury markers TNFR1, TNFR2, and KIM-1.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Medicine, General & Internal
Yingxian Sun, Jianjun Mu, Dao Wen Wang, Nanxiang Ouyang, Liying Xing, Xiaofan Guo, Chunxia Zhao, Guocheng Ren, Ning Ye, Ying Zhou, Jun Wang, Zhao Li, Guozhe Sun, Ruihai Yang, Chung-Shiuan Chen, Jiang He
Summary: The prevalence of uncontrolled hypertension is high in rural China. A multifaceted intervention led by village doctors has been found to effectively improve blood pressure control among rural residents. This strategy could be implemented in rural China and other low-income and middle-income countries.
Article
Medicine, General & Internal
Deying Liu, Yan Huang, Chensihan Huang, Shunyu Yang, Xueyun Wei, Peizhen Zhang, Dan Guo, Jiayang Lin, Bingyan Xu, Changwei Li, Hua He, Jiang He, Shiqun Liu, Linna Shi, Yaoming Xue, Huijie Zhang
Summary: Among patients with obesity, a regimen of time-restricted eating was not more beneficial with regard to reduction in body weight, body fat, or metabolic risk factors than daily calorie restriction.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Changwei Li, Yang Pan, Ruiyuan Zhang, Zhijie Huang, Davey Li, Yunan Han, Claire Larkin, Varun Rao, Xiao Sun, Tanika N. Kelly
Summary: Cardiovascular disease (CVD) is a major cause of disability and death worldwide, developing gradually throughout the life-course and influenced by genomic background. Advances in genomics, including gene-editing techniques and whole-genome sequencing, provide opportunities for discovering genomic mechanisms underlying CVD and using this knowledge for prevention and treatment.
CIRCULATION RESEARCH
(2023)
Article
Food Science & Technology
Changwei Li, Joshua D. Bundy, Ling Tian, Ruiyuan Zhang, Jing Chen, Tanika N. Kelly, Jiang He
Summary: This study aims to discover the metabolites of dietary supplements and evaluate their roles in blood pressure regulation. The results suggest that certain metabolites, such as erucate and acylcholines, are associated with blood pressure changes, and cheese intake can reduce the blood pressure-lowering effect of soy protein supplement.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Engineering, Biomedical
Yong Wang, Zikang Niu, Xiaoyu Xia, Yang Bai, Zhenhu Liang, Jianghong He, Xiaoli Li
Summary: This study utilized fast perturbational complexity index (PCIst) to diagnose and predict the prognosis of patients with disorders of consciousness (DOC). The results showed that PCIst can quantify the level of consciousness and demonstrated differences among normal healthy individuals and patients with different levels of consciousness. PCIst performed best in the 9-12 Hz frequency band.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2022)