Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide

Supramolecular interactions between β-lapachone with cyclodextrins studied using isothermal titration calorimetry and molecular modeling

(2017) Francisco H. Xavier-Junior et al.   JOURNAL OF MOLECULAR RECOGNITION

Synergistic Inhibitory Effect of Peptide–Organic Coassemblies on Amyloid Aggregation

(2016) Lin Niu et al.   ACS Nano

Monascin from Monascus-Fermented Products Reduces Oxidative Stress and Amyloid-β Toxicity via DAF-16/FOXO in Caenorhabditis elegans

(2016) Yeu-Ching Shi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Correlation between the Selectivity and the Structure of an Asymmetric Catalyst Built on a Chirally Amplified Supramolecular Helical Scaffold

(2016) Alaric Desmarchelier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

(2016) Paolo Arosio et al.   Nature Communications

Delineating the Role of Helical Intermediates in Natively Unfolded Polypeptide Amyloid Assembly and Cytotoxicity

(2015) Carole Anne De Carufel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Insights in Amyloid Beta Interactions with Human Telomerase

(2015) Jiasi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42

(2015) Olga Szczepankiewicz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simultaneous Fitting of Absorption Spectra and Their Second Derivatives for an Improved Analysis of Protein Infrared Spectra

(2015) Maurizio Baldassarre et al.   MOLECULES

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

(2015) Serene W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation

(2015) Risto Cukalevski et al.   Chemical Science

Chiral Metallohelical Complexes Enantioselectively Target Amyloid β for Treating Alzheimer’s Disease

(2014) Meng Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric triplex metallohelices with high and selective activity against cancer cells

(2014) Alan D. Faulkner et al.   Nature Chemistry

Immunoprecipitation of Amyloid Fibrils by the Use of an Antibody that Recognizes a Generic Epitope Common to Amyloid Fibrils

(2014) Erin R. Greiner et al.   PLoS One

Transition-metal-substituted polyoxometalate derivatives as functional anti-amyloid agents for Alzheimer’s disease

(2014) Nan Gao et al.   Nature Communications

Design and Synthesis of Curcumin Analogues for in Vivo Fluorescence Imaging and Inhibiting Copper-Induced Cross-Linking of Amyloid Beta Species in Alzheimer’s Disease

(2013) Xueli Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation

(2013) Yan Hou et al.   NEUROBIOLOGY OF AGING

Oleuropein Aglycone Protects Transgenic C. elegans Strains Expressing Aβ42 by Reducing Plaque Load and Motor Deficit

(2013) Luisa Diomede et al.   PLoS One

Self-Assembled Peptide-Polyoxometalate Hybrid Nanospheres: Two in One Enhances Targeted Inhibition of Amyloid β-Peptide Aggregation Associated with Alzheimer's Disease

(2013) Meng Li et al.   Small

Metallohelices with activity against cisplatin-resistant cancer cells; does the mechanism involve DNA binding?

(2013) Viktor Brabec et al.   Chemical Science

Cerium oxide caged metal chelator: anti-aggregation and anti-oxidation integrated H2O2-responsive controlled drug release for potential Alzheimer's disease treatment

(2013) Meng Li et al.   Chemical Science

Amyloid-Derived Peptide Forms Self-Assembled Monolayers on Gold Nanoparticle with a Curvature-Dependent β-Sheet Structure

(2012) Christopher P. Shaw et al.   ACS Nano

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Molecular basis of  -amyloid oligomer recognition with a conformational antibody fragment

(2012) I. Morgado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metallosupramolecular complex targeting an α/β discordant stretch of amyloid β peptide

(2012) Haijia Yu et al.   Chemical Science

Polyoxometalates as Inhibitors of the Aggregation of Amyloid β Peptides Associated with Alzheimer’s Disease

(2011) Jie Geng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Membrane-Bound Antiparallel Dimer of Rat Islet Amyloid Polypeptide

(2011) Abhinav Nath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins

(2011) Seong Il Yoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of [PtCl2(phen)] Binding Modes in Amyloid-β Peptide and the Mechanism of Aggregation Inhibition

(2011) Guolin Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comparison of ABTS/DPPH assays to measure antioxidant capacity in popular antioxidant-rich US foods

(2011) Anna Floegel et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

(2011) Jan Bieschke et al.   Nature Chemical Biology

Optically pure, water-stable metallo-helical ‘flexicate’ assemblies with antibiotic activity

(2011) Suzanne E. Howson et al.   Nature Chemistry

Roles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease

(2010) D. Allan Butterfield et al.   FREE RADICAL RESEARCH

Complete Phenotypic Recovery of an Alzheimer's Disease Model by a Quinone-Tryptophan Hybrid Aggregation Inhibitor

(2010) Roni Scherzer-Attali et al.   PLoS One

Design of small molecules that target metal-A  species and regulate metal-induced A  aggregation and neurotoxicity

(2010) J.-S. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced β -Barrel Formation of the Alzheimer's A β 25–35 Oligomers on Carbon Nanotube Surfaces: Implication for Amyloid Fibril Inhibition

(2009) Zhaoming Fu et al.   BIOPHYSICAL JOURNAL

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

 -Helix targeting reduces amyloid-  peptide toxicity

(2009) C. Nerelius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Different Hydration Changes Accompanying Copper and Zinc Binding to Amyloid β-Peptide: Water Contribution to Metal Binding

(2008) Haijia Yu et al.   CHEMBIOCHEM

Reactivity of C4-indolyl substituted 1,4-dihydropyridines toward superoxide anion (O2•) in dimethylsulfoxide

(2008) Ricardo Salazar et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

A New Class of Natural Glycopeptides with Sugar Moiety-Dependent Antioxidant Activities Derived fromGanoderma lucidumFruiting Bodies

(2008) Yalin Wu et al.   JOURNAL OF PROTEOME RESEARCH

Chirality of Amyloid Suprastructures

(2008) Noa Rubin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY