Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion

Whither vaccines?

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A Perspective on the Structural and Functional Constraints for Immune Evasion: Insights from Influenza Virus

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Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity

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Characterization of a Novel Conformational GII.4 Norovirus Epitope: Implications for Norovirus-Host Interactions

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Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State

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Replication of human noroviruses in stem cell-derived human enteroids

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Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization

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Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env

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Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza

(2015) Veronika I. Zarnitsyna et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Broad Blockade Antibody Responses in Human Volunteers after Immunization with a Multivalent Norovirus VLP Candidate Vaccine: Immunological Analyses from a Phase I Clinical Trial

(2015) Lisa C. Lindesmith et al.   PLOS MEDICINE

Particle Conformation Regulates Antibody Access to a Conserved GII.4 Norovirus Blockade Epitope

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Within-Host Evolution Results in Antigenically Distinct GII.4 Noroviruses

(2014) K. Debbink et al.   JOURNAL OF VIROLOGY

Playing Hide and Seek: How Glycosylation of the Influenza Virus Hemagglutinin Can Modulate the Immune Response to Infection

(2014) Michelle Tate et al.   Viruses-Basel

Universal immunity to influenza must outwit immune evasion

(2014) Sergio Quiñones-Parra et al.   Frontiers in Microbiology

Defining Influenza A Virus Hemagglutinin Antigenic Drift by Sequential Monoclonal Antibody Selection

(2013) Suman R. Das et al.   Cell Host & Microbe

Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy

(2013) J. Lin et al.   JOURNAL OF IMMUNOLOGY

Epitope Fluctuations in the Human Papillomavirus Are Under Dynamic Allosteric Control: A Computational Evaluation of a New Vaccine Design Strategy

(2013) Abhishek Singharoy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Fc Region of an Antibody Impacts the Neutralization of West Nile Viruses in Different Maturation States

(2013) P. D. Lee et al.   JOURNAL OF VIROLOGY

Emergence of a Norovirus GII.4 Strain Correlates with Changes in Evolving Blockade Epitopes

(2012) L. C. Lindesmith et al.   JOURNAL OF VIROLOGY

Immunogenetic Mechanisms Driving Norovirus GII.4 Antigenic Variation

(2012) Lisa C. Lindesmith et al.   PLoS Pathogens

Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution

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Genetic Mapping of a Highly Variable Norovirus GII.4 Blockade Epitope: Potential Role in Escape from Human Herd Immunity

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Monoclonal Antibody-Based Antigenic Mapping of Norovirus GII.4-2002

(2011) L. C. Lindesmith et al.   JOURNAL OF VIROLOGY

Antibody-mediated neutralization of flaviviruses: A reductionist view

(2011) Kimberly A. Dowd et al.   VIROLOGY

Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature

(2011) Michelle C. Sabo et al.   VIROLOGY

A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus

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Antibodies against conserved antigens provide opportunities for reform in influenza vaccine design

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Serological Correlate of Protection against Norovirus‐Induced Gastroenteritis

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Norovirus GII.4 Strain Antigenic Variation

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Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

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Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

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Herd Immunity to GII.4 Noroviruses Is Supported by Outbreak Patient Sera

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Evolutionary Dynamics of GII.4 Noroviruses over a 34-Year Period

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HIV-1 and influenza antibodies: seeing antigens in new ways

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Analysis of Amino Acid Variation in the P2 Domain of the GII-4 Norovirus VP1 Protein Reveals Putative Variant-Specific Epitopes

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Mechanisms of GII.4 Norovirus Persistence in Human Populations

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