The Roles of Matrix Stiffness and ß-Catenin Signaling in Endothelial-to-Mesenchymal Transition of Aortic Valve Endothelial Cells

Active tissue stiffness modulation controls valve interstitial cell phenotype and osteogenic potential in 3D culture

(2016) Bin Duan et al.   Acta Biomaterialia

Hemodynamics driven cardiac valve morphogenesis

(2016) Emily Steed et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment

(2015) Kelly M. Mabry et al.   BIOMATERIALS

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Loss of β-Catenin Promotes Chondrogenic Differentiation of Aortic Valve Interstitial Cells

(2014) Ming Fang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cells

(2014) Gretchen J. Mahler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Evaluation of a porcine model of early aortic valve sclerosis

(2014) Krista L. Sider et al.   CARDIOVASCULAR PATHOLOGY

Heterogeneous Susceptibility of Valve Endothelial Cells to Mesenchymal Transformation in Response to TNFα

(2013) Emily J. Farrar et al.   ANNALS OF BIOMEDICAL ENGINEERING

Hemodynamic and Cellular Response Feedback in Calcific Aortic Valve Disease

(2013) Sarah T. Gould et al.   CIRCULATION RESEARCH

Inflammatory Cytokines Promote Mesenchymal Transformation in Embryonic and Adult Valve Endothelial Cells

(2012) Gretchen J. Mahler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biochemical and mechanical environment cooperatively regulate skeletal muscle regeneration

(2012) Sarah Calve et al.   FASEB JOURNAL

Cell–Matrix Interactions in the Pathobiology of Calcific Aortic Valve Disease

(2011) Jan-Hung Chen et al.   CIRCULATION RESEARCH

Cyclic strain induces dual-mode endothelial-mesenchymal transformation of the cardiac valve

(2011) K. Balachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Catenin Mediates Mechanically Regulated, Transforming Growth Factor-β1–Induced Myofibroblast Differentiation of Aortic Valve Interstitial Cells

(2010) Jan-Hung Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices

(2010) Miguel Miron-Mendoza et al.   BIOMATERIALS

Calcification by Valve Interstitial Cells Is Regulated by the Stiffness of the Extracellular Matrix

(2009) Cindy Ying Yin Yip et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Active Adaptation of the Tethered Mitral Valve

(2009) Jacob P. Dal-Bianco et al.   CIRCULATION

Heart Valve Development

(2009) Michelle D. Combs et al.   CIRCULATION RESEARCH