4.7 Article

A concise synthesis of indene-based polycyclic compounds via FeCl3-catalyzed cascade cyclization

期刊

ORGANIC CHEMISTRY FRONTIERS
卷 5, 期 7, 页码 1165-1169

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8qo00004b

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资金

  1. National Natural Science Foundation of China [21372138, 21672120]
  2. Fok Ying Tong Education Foundation of China [151014]
  3. National Key Research and Development Program of China [2016YFB0401400]
  4. Department of Education of Guangdong Province [2016KCXTD005]
  5. Youth Foundation of Wuyi University [2017td01]

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An efficient and straightforward protocol to complex indene-based polycyclic compounds via the cascade cyclization of propargylic alcohols and alkenes was developed. The catalyst FeCl3, as an Earth-abundant and environment friendly transition metal salt, is attractive. This reaction proceeded through unusual C-C bond cleavage.

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