Article
Business
Mehdi Zamani, Haydar Yalcin, Ali Bonyadi Naeini, Gordana Zeba, Tugrul U. Daim
Summary: This study applies bibliographic techniques to analyze the field of emerging technologies, using citation databases and software tools to integrate and analyze research literature, and identify key actors and influential authors in the field. The study identifies Internet of Things, Intelligent Transportation Systems, and Ultrasound as the most central topics in the emerging areas, with increasing research focus.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2022)
Review
Food Science & Technology
Vicente M. Gomez-Lopez, Gianpiero Pataro, Brijesh Tiwari, Mario Gozzi, Maria Angela A. Meireles, Shaojin Wang, Buenaventura Guamis, Zhongli Pan, Hosahalli Ramaswamy, Sudhir Sastry, Florent Kuntz, Patrick J. Cullen, Sriram K. Vidyarthi, Bo Ling, Joan Miquel Quevedo, Alain Strasser, Giuseppe Vignali, Priscilla C. Veggi, Ramon Gervilla, Heidi Maria Kotilainen, Massimiliano Pelacci, Juliane Vigano, Antonio Morata
Summary: This study aims to improve the reproducibility of studies on emerging technologies for food processing by providing guidelines on reporting treatment conditions of thermal and non-thermal technologies. Different thermal and non-thermal technologies are categorized and discussed, with the highlighting of future perspectives.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Chemistry, Analytical
Lubna Luxmi Dhirani, Noorain Mukhtiar, Bhawani Shankar Chowdhry, Thomas Newe
Summary: Industry 5.0 represents a significant advancement in digital transformation, utilizing emerging technologies such as universal machines and autonomous robots to facilitate mass customization and improve production efficiencies. However, the lack of clear and consistent ethical guidelines poses challenges in compliance, potentially leading to issues such as privacy breaches and data breaches. This paper examines the ethical dimensions and dilemmas associated with these technologies and proposes strategies to address legal and regulatory concerns.
Review
Immunology
Srishti Chakravorty, Behdad Afzali, Majid Kazemian
Summary: EBV is a prevalent virus with a high infection rate, which is associated with cancer and autoimmune diseases. Despite some available treatments, their efficacy and safety are still unclear. Therefore, studying the mechanisms and therapeutic methods related to EBV-associated diseases is crucial for the development of novel effective treatments.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Food Science & Technology
Gert W. Meijer, Liisa Lahteenmaki, Richard H. Stadler, Jochen Weiss
Summary: The purpose of food processing is to make food safer, more nutritious, and tastier, while also extending its shelf life. Lack of consumer trust in food production and processing, along with the need for more transparency in the processing of food ingredients, highlights the importance of informing consumers better. To restore consumer trust, food manufacturers should be more transparent about their food processing methods.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Computer Science, Hardware & Architecture
Aamina Akbar, Sobia Jangsher, Farrukh A. Bhatti
Summary: PD-NOMA leverages users' distinct channel gains for multiplexing different signals in a single resource block in power domain, resulting in higher spectral efficiency, improved user fairness, better cell-edge throughput, increased reliability and connectivity, and low latency.
Review
Environmental Sciences
Pooja Sharma, Lohit Kumar Srinivas Gujjala, Sunita Varjani, Sunil Kumar
Summary: Industrial wastewater treatment is crucial for the safety of aquatic ecosystems and the health of humans living near water bodies. Microalgae-based technologies not only efficiently remove environmental pollutants but also produce a wide range of healthy supplements, supporting the concept of biorefinery.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Computer Science, Hardware & Architecture
Hassan Jalil Hadi, Yue Cao, Khaleeq Un Nisa, Abdul Majid Jamil, Qiang Ni
Summary: The rapid development of the UAV industry in the past two decades has led to an increase in the use of commercial UAVs. However, the lack of security measures has introduced numerous threats and vulnerabilities. This research review provides a comprehensive survey of privacy and security issues in UAVs, presents existing mitigation techniques, and discusses emerging technologies for protecting UAVs, such as blockchain, machine learning, intrusion detection systems, and secure communication protocols.
JOURNAL OF NETWORK AND COMPUTER APPLICATIONS
(2023)
Article
Multidisciplinary Sciences
Sabine Dietz, Karen F. Beazley, Christopher J. Lemieux, Colleen St Clair, Laura Coristine, Eric Higgs, Risa Smith, Marlow Pellatt, Carolynn Beaty, Edward Cheskey, Steven J. Cooke, Lindsay Crawford, Rob Davis, Graham Forbes, Fawziah (ZuZu) Gadallah, Peter Kendall, Nick Mandrak, Faisal Moola, Scott Parker, James Quayle, Justina C. Ray, Karen Richardson, Kevin Smith, James Snider, John P. Smol, William J. Sutherland, Andre Vallillee, Lori White, Alison Woodley
Summary: Horizon scanning was used to explore emerging issues likely to impact management of Canadian protected and conserved areas, with results categorized into climate change effects, Indigenous governance, integrated conservation approaches, and responses to emerging threats. The scan identified several immediate attention-worthy emerging issues to enhance preparedness and reduce threats in management.
Review
Pharmacology & Pharmacy
Rana Ajeeb, John R. Clegg
Summary: The proximity and association of cerebrospinal fluid (CSF) and the intrathecal (IT) space with deep targets in the central nervous system (CNS) parenchyma makes IT injection an attractive route for brain drug delivery. However, the effectiveness of intrathecally administered macromolecules in treating neurological diseases is still debated. Our analysis of clinical trials over the past 20 years shows an increasing interest in using IT delivery for the treatment of chronic conditions with biologics. Engineering technologies have not been extensively evaluated in these trials, but recent pre-clinical studies suggest their potential in improving CNS targeting and therapeutic outcome.
ADVANCED DRUG DELIVERY REVIEWS
(2023)
Review
Environmental Sciences
Recep Kaan Dereli, Eoghan Clifford, Eoin Casey
Summary: Solid waste management has become a global issue with waste generation surpassing population growth. Landfilling, while common, is not environmentally friendly due to greenhouse gas emissions and leachate. Co-treatment of leachate in municipal wastewater treatment plants is a widely used method, but faces sustainability challenges. New technologies are being adopted to address these issues in wastewater treatment.
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2021)
Review
Food Science & Technology
Zuhaib F. Bhat, Hina F. Bhat, Maneesha S. Mohan, Rana Muhammad Aadil, Abdo Hassoun, Abderrahmane Ait-Kaddour
Summary: Animal-derived foods are prone to microbial spoilage due to their high nutritional value and moisture content. Edible packaging is a new and effective method to control microbial growth without compromising sensory and technical properties. This review summarizes the findings of recent studies on animal foods and edible packaging systems, highlighting the use of biopolymers and bioactive ingredients for enhancing microbial stability. Nanoparticles and nanoemulsions show greater efficacy in controlling microbial spoilage compared to direct addition of bioactive agents to the packaging material. Non-thermal and emerging technologies are also explored for improved food safety and packaging functionality. Future studies should focus on developing sustainable packaging systems using readily available biopolymers and bioactive ingredients, considering their commercial viability.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Chemistry, Multidisciplinary
Younguk Cho, Sanghoon Park, Juyoung Lee, Ki Jun Yu
Summary: Neuroscience plays a crucial role in understanding advanced mental activities and developing potential therapies for neurodegenerative diseases. The field of flexible implants is gaining interest for its ability to address current challenges and pave the way for advancements in neural implants.
ADVANCED MATERIALS
(2021)
Review
Food Science & Technology
Sarah L. Jones, Kristen E. Gibson, Steven C. Ricke
Summary: Approximately 1.3 billion tons of food produced for human consumption is lost or discarded globally each year, with factors contributing to food waste ranging from manufacturing processes to consumer behavior. Current and emerging federal policies in the United States aim to address food waste generation and diversion, however, there is limited information on the composition of food waste and its impacts on treatment methods. This review discusses critical factors affecting food waste fate and explores opportunities for advancing food waste processing and products.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2021)
Review
Environmental Sciences
Minzi Wang, Michelle Wander, Steffen Mueller, Nico Martin, Jennifer B. Dunn
Summary: Transparent, consistent, and statistically reliable land use/land cover area estimates are crucial for assessing land use change and greenhouse gas emissions. This paper reviews six commonly used data sources and two remote sensing-based data products to investigate land use/land cover and change in the contiguous U.S. The study identifies research gaps and challenges in current land use studies and suggests opportunities and emerging techniques for improving reliability. Blended approaches that combine high-quality ground truth data with multitemporal imagery are needed to track non-agricultural lands vulnerable to agricultural expansion.
ENVIRONMENTAL SCIENCE & POLICY
(2022)
Article
Clinical Neurology
Aric F. Logsdon, Kendra L. Francis, Nicole E. Richardson, Shannon J. Hu, Chelsea L. Faber, Bao Anh Phan, Vy Nguyen, Naly Setthavongsack, William A. Banks, Randy L. Woltjer, C. Dirk Keene, Caitlin S. Latimer, Michael W. Schwartz, Jarrad M. Scarlett, Kimberly M. Alonge
Summary: The study found that patients with AD-related dementia experience a re-coding of their PNN-associated CS-GAGs, correlating with the progression of pathology, accumulation of p-tau, and cognitive impairment. These sulfation changes can be detected prior to classical AD pathology, potentially playing a crucial role in the development of the disease.
ALZHEIMERS & DEMENTIA
(2022)
Review
Pharmacology & Pharmacy
Stefan Trapp, Daniel Brierley
Summary: This review examines the similarities and differences between physiological systems regulated by gut-derived and neuronally produced GLP-1, discussing whether peripheral and central sources of GLP-1 are separate, linked, or redundant systems, as well as the heterogeneity or homogeneity of the brain GLP-1 system, and the implications for using GLP-1 receptor agonists as anti-obesity drugs.
BRITISH JOURNAL OF PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Daniel I. Brierley, Guillaume de Lartigue
Summary: This review focuses on the evidence supporting the involvement of the vagus nerve in mediating the effects of peripherally and centrally produced GLP-1 on eating behavior and energy balance. Recent studies using genetic, viral, and transcriptomic approaches have provided insights into the anatomical and functional organization of GLP-1-mediated gut-brain signaling pathways, challenging traditional ideas and potentially impacting the development of pharmacological treatments for obesity.
BRITISH JOURNAL OF PHARMACOLOGY
(2022)
Article
Gastroenterology & Hepatology
Anita R. Patel, Henriette Frikke-Schmidt, Olivier Bezy, Paul Sabatini, Nikolaj Rittig, Niels Jessen, Martin G. Myers, Randy J. Seeley
Summary: The study found that Lipopolysaccharide (LPS) can increase levels of GDF15 in mice, rats, and humans, but GDF15 is not necessary for inducing anorexia and weight loss in response to moderate systemic infection.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
(2022)
Review
Medicine, Research & Experimental
Michelle A. Erickson, William A. Banks
Summary: Disruption of the blood-brain barrier (BBB) can occur through different mechanisms and pathways, resulting in different neurological insults. The importance of transcellular pathways in BBB disruption has been highlighted. Transcytotic mechanisms are less clearly linked to permeability compared to membrane spanning canaliculi and fenestrations. Cellular components involved in transcellular mechanisms of BBB disruption are being discovered and measured, adding to our classic knowledge based on ultrastructural studies.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2022)
Article
Pharmacology & Pharmacy
William A. Banks, Pericles Calias, Kim M. Hansen, Kristin M. Bullock, Kory Engelke
Summary: This study evaluated the uptake and distribution of kleptose in the brain and spinal cord after intranasal and intrathecal delivery. The results showed that intrathecal delivery resulted in higher distribution in the brain compared to intranasal delivery.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2022)
Article
Medicine, Research & Experimental
Ki-Suk Kim, Bailey Ce Peck, Yu-Han Hung, Kieran Koch-Laskowski, Landon Wood, Priya H. Dedhia, Jason R. Spence, Randy J. Seeley, Praveen Sethupathy, Darleen A. Sandoval
Summary: This study found that vertical sleeve gastrectomy (VSG) increases the number of hormone-secreting enteroendocrine cells (EECs) in the intestine through bile acid signaling, which drives intestinal stem cell fate towards EEC differentiation.
Review
Endocrinology & Metabolism
Mario Perello, Suzanne L. Dickson, Jeffrey M. Zigman, Lorenzo Leggio
Summary: The stomach-derived peptide ghrelin, discovered in 1999, is an endogenous agonist of the growth hormone secretagogue receptor (GHSR) and plays key roles in various physiological functions. Its non-acylated form, desacyl-ghrelin, has a less well-understood physiological role. To establish a consistent nomenclature, experts in the field have proposed using the terms ghrelin and desacyl-ghrelin for the hormones, GHSR for the receptor, and LEAP2 for a recently recognized GHSR antagonist/inverse agonist.
JOURNAL OF NEUROENDOCRINOLOGY
(2023)
Article
Physiology
Anita R. Patel, Henriette Frikke-Schmidt, Paul V. Sabatini, Alan C. Rupp, Darleen A. Sandoval, Martin G. Myers, Randy J. Seeley
Summary: Deoxynivalenol (DON), a mycotoxin contaminating grain, induces nausea, emesis, and anorexia. The study found that GLP-1 is not necessary for DON-induced effects on food intake and visceral illness. Additionally, the study showed that the calcium-sensing receptor (CaSR) on GFRAL neurons may play a role in DON signaling, but neither GLP-1 signaling nor GFRAL signaling and neurons are required for DON-induced visceral illness or anorexia.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2023)
Article
Clinical Neurology
Erik Schele, Iris Stoltenborg, Anders Xie, Fiona Peris-Sampedro, Roger A. H. Adan, Suzanne L. Dickson
Summary: This study aims to investigate the activation of orexin neurons during severe anorectic state and the potential of suvorexant, a dual orexin receptor antagonist, in reducing excessive physical activity. The findings indicate that a large population of orexin neurons are activated in the ABA mouse model and that peripheral administration of suvorexant decreases food anticipatory activity. Orexin may be a suitable target for treating hyperactivity in AN, and further research is recommended to examine the efficacy of suvorexant in aiding AN patients in controlling excessive activity.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2023)
Review
Medicine, Research & Experimental
Rachel C. Knopp, Michelle A. Erickson, Elizabeth M. Rhea, May J. Reed, William A. Banks
Summary: The blood-brain barrier (BBB) is an important interface that regulates communication between the brain and blood. It is comprised of brain endothelial cells and is surrounded by supportive brain cell types. Recent studies have shown that the BBB undergoes dysfunction during aging and in diseases, and cellular senescence, one of the hallmarks of aging, is believed to play a role in these changes. This review summarizes the known age-related changes at the BBB, evaluates the impact of cellular senescence in neurodegenerative diseases, discusses insights from in vitro and in vivo studies, and explores mechanisms by which cellular senescence affects BBB function.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2023)
Editorial Material
Endocrinology & Metabolism
Samuel Klein, Randy J. Seeley
Summary: Many individuals with obesity and type 2 diabetes experience diabetes remission after Roux-en-Y gastric bypass surgery, but there is disagreement regarding the underlying mechanisms. We present our perspective on conflicting datasets suggesting that the remission could be attributed solely to weight loss or weight loss-independent factors.
Article
Psychology, Biological
D. M. Pfabigan, E. R. Frogner, E. Schele, P. M. Thorsby, B. S. Skalhegg, S. L. Dickson, U. Sailer
Summary: Variations in ghrelin concentrations may affect the processing of touch as a social reward in humans, with higher ghrelin concentrations associated with a lower reward value for touch.
Article
Endocrinology & Metabolism
Mireia Montaner, Jessica Denom, Wanqing Jiang, Christophe Magnan, Stefan Trapp, Hirac Gurden
Summary: The study investigates the role of the GLP-1/glucagon-like peptide-1 receptor (GLP-1R) system in the olfactory bulb (OB) in foraging behavior and odor-evoked Cephalic Phase Insulin Release (CPIR). The results demonstrate that GLP-1OB controls olfactory foraging and is required for odor-evoked CPIR.
MOLECULAR METABOLISM
(2023)
Article
Endocrinology & Metabolism
Hua Dong, Wenfei Sun, Yang Shen, Miroslav Balaz, Lucia Balazova, Lianggong Ding, Mona Loeffler, Bradford Hamilton, Nora Kloeting, Matthias Blueher, Heike Neubauer, Holger Klein, Christian Wolfrum
Summary: Dong and Sun et al. demonstrate the inhibitory role of adipogenesis regulatory cells in murine white adipose tissue through RSPO2. They show that RSPO2 regulates the maturation of early progenitor cells via Lgr4. This study highlights the importance of cellular crosstalk in adipogenesis and its impact on adipose tissue homeostasis.
Article
Endocrinology & Metabolism
Liujun Chen, Lisha Li, Donghong Cui, Yiheng Huang, Haibin Tong, Haleh Zabihi, Shuxia Wang, Yadan Qi, Ted Lakowski, Lin Leng, Suixin Liu, Hong Wu, Lawrence H. Young, Richard Bucala, Dake Qi
Summary: Attenuation of adipose hormone sensitive lipase (HSL) may impair lipolysis and exacerbate obesity. Cytokine macrophage migration inhibitory factor (MIF) plays a role in regulating adipose HSL and adipocyte hypertrophy. Both intracellular and extracellular MIF have opposing effects on HSL, but extracellular action predominates to downregulate HSL and exacerbate obesity development during high-fat diet (HFD).
MOLECULAR METABOLISM
(2024)
Article
Endocrinology & Metabolism
Mengyang Tang, Yi Zhang, Rong Zhang, Yuemei Zhang, Jiangfei Zheng, Daixi Wang, Xinyu Wang, Jing Yan, Cheng Hu
Summary: This study aimed to explore the role of GPSM1 in POMC neurons and the underlying mechanisms in metabolic homeostasis. Through various molecular, biochemical, immunofluorescent, immunohistochemical analyses, and cell culture studies, the study revealed the pathophysiological role of GPSM1 in POMC neurons and its regulation of POMC neuron activity.
MOLECULAR METABOLISM
(2024)
