Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic Brain Injury: Impact on Neurofunctional Outcome and Biomarkers of Oxidative Stress and Inflammation

Performance and Side Effects of Supplementation with N-Acetylcysteine: A Systematic Review and Meta-Analysis

(2017) Kate Rhodes et al.   SPORTS MEDICINE

Protective Effect of N-Acetylcysteine Amide on Blast-Induced Increase in Intracranial Pressure in Rats

(2017) Usmah Kawoos et al.   Frontiers in Neurology

Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children

(2017) Robert S. B. Clark et al.   PLoS One

Inflammatory cytokine and chemokine profiles are associated with patient outcome and the hyperadrenergic state following acute brain injury

(2016) Alex P. Di Battista et al.   Journal of Neuroinflammation

A minireview on N -acetylcysteine: An old drug with new approaches

(2016) Ines Elbini Dhouib et al.   LIFE SCIENCES

Biomarkers of Glycocalyx Injury are Associated with Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage: A Case Series Supporting a New Hypothesis

(2016) Josh D. Bell et al.   Neurocritical Care

The Post-Anaesthesia N-acetylcysteine Cognitive Evaluation (PANACEA) trial: study protocol for a randomised controlled trial

(2016) David R. Skvarc et al.   Trials

Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes

(2016) Qiuhua Shen et al.   Worldviews on Evidence-Based Nursing

Traumatic Brain Injury and Mitochondrial Dysfunction

(2015) John B. Hiebert et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

S100B protein as a screening tool for computed tomography findings after mild traumatic brain injury: Systematic review and meta-analysis

(2015) Kamran Heidari et al.   BRAIN INJURY

N-Acetylcysteine as an Adjunctive Therapy to Risperidone for Treatment of Irritability in Autism

(2015) Mohammadali Nikoo et al.   CLINICAL NEUROPHARMACOLOGY

Neuroprotective effects of N-acetylcysteine amide on experimental focal penetrating brain injury in rats

(2015) Mattias Günther et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review

(2015) Deepmala et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

Effect of N-acetylcysteine on cardiac injury and oxidative stress after abdominal aortic aneurysm repair: A randomized controlled trial

(2015) K. M. MAHMOUD et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Neurobehavioral sequelae of traumatic brain injury: evaluation and management

(2015) THOMAS W. MCALLISTER   World Psychiatry

Neuroprotection Induced by N-acetylcysteine and Selenium Against Traumatic Brain Injury-Induced Apoptosis and Calcium Entry in Hippocampus of Rat

(2014) Mustafa Nazıroğlu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI

(2014) Jignesh D. Pandya et al.   EXPERIMENTAL NEUROLOGY

The Efficacy of AdjunctiveN-Acetylcysteine in Major Depressive Disorder

(2014) Michael Berk et al.   JOURNAL OF CLINICAL PSYCHIATRY

Antenatal Pharmacokinetics and Placental Transfer of N-Acetylcysteine in Chorioamnionitis for Fetal Neuroprotection

(2014) Donald B. Wiest et al.   JOURNAL OF PEDIATRICS

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action

(2014) Olivia Dean et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Mitochondria: hub of injury responses in the developing brain

(2014) Henrik Hagberg et al.   LANCET NEUROLOGY

Oral cysteamine bitartrate and N-acetylcysteine for patients with infantile neuronal ceroid lipofuscinosis: a pilot study

(2014) Sondra W Levin et al.   LANCET NEUROLOGY

N-Acetylcysteine and Selenium Modulate Oxidative Stress, Antioxidant Vitamin and Cytokine Values in Traumatic Brain Injury-Induced Rats

(2014) Nilgün Şenol et al.   NEUROCHEMICAL RESEARCH

Efficacy of N-Acetyl Cysteine in Traumatic Brain Injury

(2014) Katharine Eakin et al.   PLoS One

The chemistry and biological activities of N-acetylcysteine

(2013) Yuval Samuni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Biomarkers for the Clinical Differential Diagnosis in Traumatic Brain Injury-A Systematic Review

(2013) Shoji Yokobori et al.   CNS Neuroscience & Therapeutics

The pathophysiology of traumatic brain injury at a glance

(2013) M. Prins et al.   Disease Models & Mechanisms

Instruments for Assessing Risk of Bias and Other Methodological Criteria of Published Animal Studies: A Systematic Review

(2013) David Krauth et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury

(2013) Margalit Haber et al.   EXPERIMENTAL NEUROLOGY

N-Acetylcysteine amide: a derivative to fulfill the promises of N-Acetylcysteine

(2013) K. Sunitha et al.   FREE RADICAL RESEARCH

Animal models of traumatic brain injury

(2013) Ye Xiong et al.   NATURE REVIEWS NEUROSCIENCE

Amelioration of Acute Sequelae of Blast Induced Mild Traumatic Brain Injury by N-Acetyl Cysteine: A Double-Blind, Placebo Controlled Study

(2013) Michael E. Hoffer et al.   PLoS One

Effects of Antioxidant Treatment on Blast-Induced Brain Injury

(2013) Xiaoping Du et al.   PLoS One

Metoprolol vs. carvedilol or carvedilol plus N-acetyl cysteine on post-operative atrial fibrillation: a randomized, double-blind, placebo-controlled study

(2012) M. Ozaydin et al.   EUROPEAN HEART JOURNAL

Antioxidant treatment reduces blast-induced cochlear damage and hearing loss

(2012) Donald L. Ewert et al.   HEARING RESEARCH

Effects of Selenium on Calcium Signaling and Apoptosis in Rat Dorsal Root Ganglion Neurons Induced by Oxidative Stress

(2012) Abdülhadi Cihangir Uğuz et al.   NEUROCHEMICAL RESEARCH

Antioxidant therapies in traumatic brain and spinal cord injury

(2011) Mona Bains et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The involvement of Na+, K+-ATPase activity and free radical generation in the susceptibility to pentylenetetrazol-induced seizures after experimental traumatic brain injury

(2011) Luiz Fernando Almeida Silva et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Modified Romberg Balance Test

(2011) Yuri Agrawa et al.   OTOLOGY & NEUROTOLOGY

Mechanisms of blast induced brain injuries, experimental studies in rats

(2010) M. Risling et al.   NEUROIMAGE

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Minocycline Synergizes with N-Acetylcysteine and Improves Cognition and Memory Following Traumatic Brain Injury in Rats

(2010) Samah G. Abdel Baki et al.   PLoS One

A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats

(2009) Samah G. Abdel Baki et al.   BRAIN RESEARCH

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

(2009) Fredrik Clausen et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

ATTENUATION OF PULMONARY INFLAMMATION AFTER EXPOSURE TO BLAST OVERPRESSURE BY N-ACETYLCYSTEINE AMIDE

(2009) Mikulas Chavko et al.   SHOCK

The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

(2009) Alessandro Liberati et al.   PLOS MEDICINE

N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

(2008) Seetal Dodd et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine

(2008) Gang Chen et al.   MEDIATORS OF INFLAMMATION

Temporal and Spatial Characteristics of Gait During Performance of the Dynamic Gait Index in People With and People Without Balance or Vestibular Disorders

(2008) Gregory F Marchetti et al.   PHYSICAL THERAPY