Coagulation Factor X Regulated by CASC2c Recruited Macrophages and Induced M2 Polarization in Glioblastoma Multiforme

Dihydrofisetin exerts its anti-inflammatory effects associated with suppressing ERK/p38 MAPK and Heme Oxygenase-1 activation in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced mice paw edema

(2018) Kai Kai Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p

(2018) Yufeng Zhou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

New insights into long noncoding RNAs and their roles in glioma

(2018) Zixuan Peng et al.   Molecular Cancer

Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction

(2018) Mallika Ghosh et al.   PLoS One

Schizophrenia-associated rs4702 G allele-specific downregulation of FURIN expression by miR-338-3p reduces BDNF production

(2018) Yu Hou et al.   SCHIZOPHRENIA RESEARCH

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

CASC2c as an unfavorable prognosis factor interacts with miR-101 to mediate astrocytoma tumorigenesis

(2017) Changhong Liu et al.   Cell Death & Disease

Environmental stimuli shape microglial plasticity in glioma

(2017) Stefano Garofalo et al.   eLife

Insulin Growth Factor 1 Protects Neural Stem Cells Against Apoptosis Induced by Hypoxia Through Akt/Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase (Akt/MAPK/ERK) Pathway in Hypoxia-Ishchemic Encephalopathy

(2017) Bing Zhao et al.   MEDICAL SCIENCE MONITOR

Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes

(2017) Peiyao Li et al.   Frontiers in Immunology

Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway

(2017) Ruiling Liu et al.   PLoS One

Tumor infiltrating immune cells in gliomas and meningiomas

(2016) Patrícia Domingues et al.   BRAIN BEHAVIOR AND IMMUNITY

The Multifaceted Role of Perivascular Macrophages in Tumors

(2016) Claire E. Lewis et al.   CANCER CELL

The D Domain of LRRC4 anchors ERK1/2 in the cytoplasm and competitively inhibits MEK/ERK activation in glioma cells

(2016) Zeyou Wang et al.   Journal of Hematology & Oncology

The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation

(2016) Preeta Dasgupta et al.   Science Signaling

Low expression of miR-381 is a favorite prognosis factor and enhances the chemosensitivity of osteosarcoma

(2016) Yunchao Li et al.   Oncotarget

The adaptor protein insulin receptor substrate 2 inhibits alternative macrophage activation and allergic lung inflammation

(2016) Preeta Dasgupta et al.   Science Signaling

Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells

(2016) Ji heon Rhim et al.   Scientific Reports

MicroRNA-338-3p functions as tumor suppressor in breast cancer by targeting SOX4

(2015) YING JIN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-338-3p suppresses tumor growth of ovarian epithelial carcinoma by targeting Runx2

(2015) CHUNYAN WEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Immunity, inflammation, and cancer: an eternal fight between good and evil

(2015) Shabnam Shalapour et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased VEGF and Decreased SDF-1α in Patients with Silent Brain Infarction Are Associated with Better Prognosis after First-Ever Acute Lacunar Stroke

(2015) Hyuk Sung Kwon et al.   Journal of Stroke & Cerebrovascular Diseases

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles

(2015) Virginie Rabolli et al.   Particle and Fibre Toxicology

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

Increased VEGF and Decreased SDF-1α in Patients with Silent Brain Infarction Are Associated with Better Prognosis after First-Ever Acute Lacunar Stroke

(2015) Hyuk Sung Kwon et al.   Journal of Stroke & Cerebrovascular Diseases

Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling

(2015) Jun Zhang et al.   Oncotarget

Crosstalk between ERK, AKT, and cell survival

(2014) Paul Dent   CANCER BIOLOGY & THERAPY

A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular Carcinoma

(2014) Ji-hang Yuan et al.   CANCER CELL

Alpha2beta1 integrin promotes T cell survival and migration through the concomitant activation of ERK/Mcl-1 and p38 MAPK pathways

(2014) Dalila Naci et al.   CELLULAR SIGNALLING

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion

(2014) Emelie Karnevi et al.   IMMUNOLOGY AND CELL BIOLOGY

microRNA-338-3p functions as a tumor suppressor in human non-small-cell lung carcinoma and targets Ras-related protein 14

(2014) JIANGTAO SUN et al.   Molecular Medicine Reports

Shaping macrophages function and innate immunity by bile acids: Mechanisms and implication in cholestatic liver diseases

(2014) Yvon Calmus et al.   Clinics and Research in Hepatology and Gastroenterology

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

(2013) Yan Zhang et al.   CELL RESEARCH

Crosstalk between PI3 Kinase/PDK1/Akt/Rac1 and Ras/Raf/MEK/ERK Pathways Downstream PDGF Receptor

(2013) Emma Tabe Eko Niba et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Coagulation factor Xa induces an inflammatory signalling by activation of protease-activated receptors in human atrial tissue

(2013) Alicja Bukowska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches

(2013) Caroline Baer et al.   EXPERIMENTAL CELL RESEARCH

Integrin signaling in control of tumor growth and progression

(2013) Jiangling Xiong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

 1 1 Integrin-Mediated Adhesion Inhibits Macrophage Exit from a Peripheral Inflammatory Lesion

(2013) H. M. Becker et al.   JOURNAL OF IMMUNOLOGY

Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response

(2013) Malgorzata Sielska et al.   JOURNAL OF PATHOLOGY

Radiotherapy plus Concomitant Adjuvant Temozolomide for Glioblastoma: Japanese Mono-Institutional Results

(2013) Takahiro Oike et al.   PLoS One

Natural and Induced T Regulatory Cells in Cancer

(2013) Dennis O. Adeegbe et al.   Frontiers in Immunology

Tumor-Associated Macrophages in Glioma: Friend or Foe?

(2013) Benjamin C. Kennedy et al.   Journal of Oncology

Macrophages in Tumor Microenvironments and the Progression of Tumors

(2012) Ning-Bo Hao et al.   Clinical & Developmental Immunology

F10 gene hypomethylation, a putative biomarker for glioma prognosis

(2011) Xiaoping Liu et al.   JOURNAL OF NEURO-ONCOLOGY

miR-338-3p suppresses invasion of liver cancer cell by targeting smoothened

(2011) Xiao-Hui Huang et al.   JOURNAL OF PATHOLOGY

Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells

(2011) Minfeng Shu et al.   Molecular Cancer

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development

(2011) S M Pyonteck et al.   ONCOGENE

Cancer-related inflammation: Common themes and therapeutic opportunities

(2011) Frances R. Balkwill et al.   SEMINARS IN CANCER BIOLOGY

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Coagulation Factor Xa inhibits cancer cell migration via Protease-activated receptor-1 activation

(2009) Keren Borensztajn et al.   THROMBOSIS RESEARCH

Factor Xa Stimulates Proinflammatory and Profibrotic Responses in Fibroblasts via Protease-Activated Receptor-2 Activation

(2008) Keren Borensztajn et al.   AMERICAN JOURNAL OF PATHOLOGY

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY

Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells

(2008) Xiaofeng Jiang et al.   THROMBOSIS AND HAEMOSTASIS

Factor Xa: at the crossroads between coagulation and signaling in physiology and disease

(2008) Keren Borensztajn et al.   TRENDS IN MOLECULAR MEDICINE