Zoledronate Triggers Vδ2 T Cells to Destroy and Kill Spheroids of Colon Carcinoma: Quantitative Image Analysis of Three-Dimensional Cultures

Cancer immunotherapy beyond immune checkpoint inhibitors

(2018) Julian A. Marin-Acevedo et al.   Journal of Hematology & Oncology

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

(2018) Victor H. Engelhard et al.   JOURNAL OF IMMUNOLOGY

In Vitro Killing of Colorectal Carcinoma Cells by Autologous Activated NK Cells is Boosted by Anti-Epidermal Growth Factor Receptor-induced ADCC Regardless of RAS Mutation Status

(2018) Ilaria Turin et al.   JOURNAL OF IMMUNOTHERAPY

Gamma-delta (γδ) T cells: friend or foe in cancer development?

(2018) Yijing Zhao et al.   Journal of Translational Medicine

Emerging tumor spheroids technologies for 3D in vitro cancer modeling

(2018) Tânia Rodrigues et al.   PHARMACOLOGY & THERAPEUTICS

Rational Design of Mouse Models for Cancer Research

(2018) Marietta Landgraf et al.   TRENDS IN BIOTECHNOLOGY

Peripheral White Blood Cell Subsets in Metastatic Colorectal Cancer Patients Treated with Cetuximab: The Potential Clinical Relevance

(2018) Ivana Z. Matić et al.   Frontiers in Immunology

Three-dimensional cell culture models for anticancer drug screening: Worth the effort?

(2017) Eddy-Tim Verjans et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Current Advances in γδ T Cell-Based Tumor Immunotherapy

(2017) Elena Lo Presti et al.   Frontiers in Immunology

Zoledronate can induce colorectal cancer microenvironment expressing BTN3A1 to stimulate effector γδ T cells with antitumor activity

(2017) Maria Raffaella Zocchi et al.   OncoImmunology

Mouse models of intestinal inflammation and cancer

(2016) Aya M. Westbrook et al.   ARCHIVES OF TOXICOLOGY

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

The Flaws and Human Harms of Animal Experimentation

(2015) AYSHA AKHTAR   CAMBRIDGE QUARTERLY OF HEALTHCARE ETHICS

Impact of the spheroid model complexity on drug response

(2015) Oliver Ingo Hoffmann et al.   JOURNAL OF BIOTECHNOLOGY

Molecules and Mechanisms Implicated in the Peculiar Antigenic Activation Process of Human Vγ9Vδ2 T Cells

(2015) Christelle Harly et al.   Frontiers in Immunology

Mechanisms of tumor escape from immune system: Role of mesenchymal stromal cells

(2014) Alessandro Poggi et al.   IMMUNOLOGY LETTERS

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

(2013) Stefano Vavassori et al.   NATURE IMMUNOLOGY

Phase II failures: 2008–2010

(2011) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

(2011) Makoto Kondo et al.   Jove-Journal of Visualized Experiments

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Finding the tumor copycat: Therapy fails, patients don't

(2010) Lee M Ellis et al.   NATURE MEDICINE

Efficient Killing of Human Colon Cancer Stem Cells by    T Lymphocytes

(2009) M. Todaro et al.   JOURNAL OF IMMUNOLOGY

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine